Summary
A differentiation can be made between the LC in normal brain, in SDAT and PD for diagnostic purposes, based on the findings concerning the morphological alterations of the TH-immunoreactive neurons, the topographical distribution of neuron loss within the length of the LC, and, to some extent, the total reduction in cell number.
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References
Chan-Palay V, Asan E (1989a) Quantitation of catecholamine neurons in the locus coeruleus in human brains of young and older adults. J Comp Neurol 287: 357–372
Chan-Palay V, Asan E (1989b) Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer’s type, and in Parkinson’s disease with and without dementia. J Comp Neurol 287: 373–392
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© 1990 Springer-Verlag Wien
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Chan-Palay, V., Asan, E. (1990). Alterations in catecholamine neurons in the locus coeruleus in dementias of Alzheimer’s and Parkinson’s disease. In: Maurer, K., Riederer, P., Beckmann, H. (eds) Alzheimer’s Disease. Epidemiology, Neuropathology, Neurochemistry, and Clinics. Key Topics in Brain Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3396-5_25
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DOI: https://doi.org/10.1007/978-3-7091-3396-5_25
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82197-8
Online ISBN: 978-3-7091-3396-5
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