Abstract
Cnidarians are constantly exposed to microbes. It is therefore not too surprising that molecular analyses have revealed a variety of molecular pathways used by cnidarians to respond to microbial exposure. When approaching the epithelium of a cnidarian, microbes first encounter extracellular germline-encoded surface receptors that recognize microbe-associated molecular patterns (MAMPs). Examples of MAMPs include lipopolysaccharides (LPSs), peptidoglycan (PGN), flagellin, and microbial nucleic acids. Perception of a MAMP at the cell surface is achieved by Toll-like receptors (TLRs) which then initiate MAMP-triggered immunity. In this chapter, we consider one by one the major components used by the cnidarians host to interact with the microbes.
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Bosch, T.C.G., Miller, D.J. (2016). Negotiations Between Early Evolving Animals and Symbionts. In: The Holobiont Imperative. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1896-2_5
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DOI: https://doi.org/10.1007/978-3-7091-1896-2_5
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