Abstract
Arrhythmias account for over 300,000 annual deaths in the USA, and approximately half of all deaths are associated with heart disease. Mechanisms underlying arrhythmia risk are complex; however, work in humans and animal models over the past 20 years has identified a host of molecular pathways linked with both arrhythmia substrates and triggers. This chapter will focus on select arrhythmia pathways solved by linking human clinical and genetic data with animal models.
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Adelman, S., Sturm, A.C., Mohler, P.J. (2016). Molecular Pathways and Animal Models of Arrhythmias. In: Rickert-Sperling, S., Kelly, R., Driscoll, D. (eds) Congenital Heart Diseases: The Broken Heart. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1883-2_63
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DOI: https://doi.org/10.1007/978-3-7091-1883-2_63
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-1882-5
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