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Zerebelläre Kontrolle der Okulomotorik und mögliche Therapie zerebellärer Störungen

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Zusammenfassung

Schon lange ist bekannt, dass das Kleinhirn an der Kontrolle von Bewegungen und insbesondere von Augenbewegungen beteiligt ist. Andererseits kann man Augenbewegungen auch nach kompletter Entfernung des Kleinhirnes noch beobachten. An der Kontrolle der verschiedenen Aspekte von Augenbewegungen sind unterschiedliche Anteile des Kleinhirnes beteiligt. Augenfolgebewegungen, die sich phylogenetisch erst spät entwickelt haben und eigentlich im Wesentlichen nur bei Tieren mit frontalen Augen und einer Foeva zu beobachten sind, werden vorwiegend über den Flokkulus/Paraflokkulus und den damit eng verbundenen medialen Vestibulariskern verschaltet. Letztlich sind der Flokkulus und Paraflokkulus auch an der Anpassung des vestibulo-oculären Reflexes beteiligt und Anteile des Nodulus und der Uvula an der Integration von Bogengangssignalen und Otolitheneingänge.

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Copyright information

© Springer-Verlag Wien 2014

Authors and Affiliations

  1. 1.Neurologische Klinik und PoliklinikKlinikum der Ludwig-Maximilians-Universität München, Klinikum GroßhadernMünchenDeutschland
  2. 2.Neurologische Gemeinschaftspraxis am MarienplatzMünchenDeutschland
  3. 3.Neurologische Klinik und PoliklinikKlinikum der Ludwig-Maximilians-UniversitätMünchenDeutschland

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