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Movement Disorders in Children

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Movement Disorders Curricula

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Abstract

Movement disorders (MDs) in children have some peculiarities compared with adults. In front of a pediatric patient with a specific type of movement disorder, usually the etiologies are different from those considered in an adult, and by the other hand, the clinical manifestations are different because they are influenced by the age of onset of a certain disease. In children with movement disorders, hyperkinetic movements predominate; in adults bradykinesia is much more prevalent. Moreover, certain disorders occur almost exclusively in children, as is the case of transient movement disorders, or are much more frequent as metabolic and autoimmune diseases.

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References

  1. Fernandez-Alvarez E. Transient movement disorders in children. J Neurol. 1998;245:1.

    Article  CAS  PubMed  Google Scholar 

  2. Shuper A, Zalzberg J, Weitz R, Mimouni M. Jitteriness beyond the neonatal period: a benign pattern of movement in infancy. J Child Neurol. 1991;6(3):243–5.

    Article  CAS  PubMed  Google Scholar 

  3. Kaddurah AK, Holmes GL. Benign neonatal sleep myoclonus: history and semiology. Pediatr Neurol. 2009;40:343–6.

    Article  PubMed  Google Scholar 

  4. Maurer VO, Rizzi M, Bianchetti MG, Ramelli GP. Benign neonatal sleep myoclonus: a review of the literature. Pediatrics. 2010;125(4):e919–24.

    Article  PubMed  Google Scholar 

  5. Caraballo RH, Capovilla G, Vigevano F, Beccaria F, Specchio N, Fejerman N. The spectrum of benign myoclonus of early infancy: clinical and neurophysiologic features in 102 patients. Epilepsia. 2009;50(5):1176–83.

    Article  PubMed  Google Scholar 

  6. Bonnet C, Roubertie A, Doummar D, Bahi-Buisson N, Cock VC, Roze E. Developmental and benign movement disorders in childhood. Mov Disord. 2010;25(10):1317–34.

    Article  PubMed  Google Scholar 

  7. Gottlob I, Wizov SS, Reinecke RD. Spasmus nutans. A long-term follow-up. Invest Ophthalmol Vis Sci. 1995;36(13):2768–71.

    CAS  PubMed  Google Scholar 

  8. Wizov SS, Reinecke RD, Bocarnea M, Gottlob I. A comparative demographic and socioeconomic study of spasmus nutans and infantile nystagmus. Am J Ophthalmol. 2002;133:256–62.

    Article  PubMed  Google Scholar 

  9. Drigo P, Carli G, Laverda AM. Benign paroxysmal torticollis of infancy. Brain Dev. 2000;22(3):169–72.

    Article  CAS  PubMed  Google Scholar 

  10. Giffin NJ, Benton S, Goadsby PJ. Benign paroxysmal torticollis of infancy: four new cases and linkage to CACNA1A mutation. Dev Med Child Neurol. 2002;44(7):490–3.

    Article  CAS  PubMed  Google Scholar 

  11. Campistol J, Prats JM, Garaizar C. Benign paroxysmal tonic upgaze in childhood with ataxia: a neuro-ophthalmological syndrome of familial origin? Dev Med Child Neurol. 1993;35:436–9.

    Article  CAS  PubMed  Google Scholar 

  12. Ouvrier R, Billson F. Paroxysmal tonic upgaze of childhood-a review. Brain Dev. 2005;27(3):185–8.

    Article  PubMed  Google Scholar 

  13. Good WV, Hou C, Carden SM. Transient, idiopathic nystagmus in infants. Dev Med Child Neurol. 2003;45:304–7.

    Article  PubMed  Google Scholar 

  14. Calado R, Monteiro JP, Fonseca MJ. Transient idiopathic dystonia in infancy. Acta Paediatr. 2011;100(4):624–7.

    Article  PubMed  Google Scholar 

  15. Vanasse M, Bedard P, Andermann F. Shuddering attacks in children: an early clinical manifestation of essential tremor. Neurology. 1976;26:1027–30.

    Article  CAS  PubMed  Google Scholar 

  16. Fernandez-Alvarez E, Aicardi J, Bathien N. Movement disorders in children. New York: Cambridge University Press; 2001.

    Google Scholar 

  17. Pons R. The phenotypic spectrum of paediatric neurotransmitter diseases and infantile parkinsonism. J Inherit Metab Dis. 2009;32:321–32.

    Article  CAS  PubMed  Google Scholar 

  18. Kurian MA, Zhen J, Cheng SY, Li Y, Mordekar SR, Jardine P, Morgan NV, Meyer E, Tee L, et al. Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia. J Clin Invest. 2009;119(6):1595–603.

    CAS  PubMed  PubMed Central  Google Scholar 

  19. Garcia Cazorla A, Rabier D, Touati G, Chadefaux-Vekemans B, Marsac C, de Lonlay P, Saudubray JM. Pyruvate carboxylase deficiency: metabolic characteristics and new neurological aspects. Ann Neurol. 2006;59:121–12.

    Article  PubMed  Google Scholar 

  20. Assmann B, Surtees R, Hoffmann GF. Approach to the diagnosis of neurotransmitter diseases exemplified by the differential diagnosis of childhood-onset dystonia. Ann Neurol. 2003;54 Suppl 6:S18–24.

    Article  CAS  PubMed  Google Scholar 

  21. Garcia-Cazorla A, Wolf NI, Serrano M, Perez-Duenas B, Pineda M, Campistol J, et al. Inborn errors of metabolism and motor disturbances in children. J Inherit Metab Dis. 2009;32:618–29.

    Article  CAS  PubMed  Google Scholar 

  22. Temudo T, Martins E, Poças F, Cruz R, Vilarinho L. Maple syrup disease presenting as paroxysmal dystonia. Ann Neurol. 2004;56(5):749–50.

    Article  PubMed  Google Scholar 

  23. Suls A, Dedeken P, Goffin K, Van Esch H, Dupont P, Cassiman D, et al. Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1. Brain. 2008;131(Pt 7):1831–44.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Sedel F, Saudubray J-M, Roze E, Agid Y, Vidailhet M. Movement disorders and inborn errors of metabolism in adults: a diagnostic approach. J Inherit Metab Dis. 2008;31:308–18.

    Article  CAS  PubMed  Google Scholar 

  25. Gouider-Khouja N, Kraoua I, Benrrhouma H, Fraj N, Rouiissi A. Movement disorders in neuro-metabolic diseases. Eur J Paediatr Neurol. 2010;14:304–7.

    Article  PubMed  Google Scholar 

  26. Ozand PT, Gascon GG, Al Essa M, Joshi S, Al Jishi E, Bakheet S, et al. Biotin-responsive basal ganglia disease: a novel entity. Brain. 1998;121(Pt 7):1267–79.

    Article  PubMed  Google Scholar 

  27. Demiroren K, Yavuz H, Cam L, Oran B, Karaaslan S, Demiroren S. Sydenham’s chorea: a clinical follow-up of 65 patients. J Child Neurol. 2007;22:550–4.

    Article  PubMed  Google Scholar 

  28. Cardoso F, Silva CE, Mota CC. Sydenham’s chorea in 50 consecutive patients with rheumatic fever. Mov Disord. 1997;12:701–3.

    Article  CAS  PubMed  Google Scholar 

  29. Paz JA, Silva CAA, Marques-Dias MJ. Randomized double-blind study with prednisone in Sydenham’s chorea. Pediatr Neurol. 2006;34:264–9.

    Article  PubMed  Google Scholar 

  30. Swedo SE. Sydenham’s chorea. A model for childhood autoimmune neuropsychiatric disorders. JAMA. 1994;272:1788–91.

    Article  CAS  PubMed  Google Scholar 

  31. Baizabal-Carvallo JF M.D., M.Sc., Jankovic J M.D. Movement disorders in autoimmune diseases. Mov Disord. 2012;27(8):935.

    Article  CAS  PubMed  Google Scholar 

  32. Garvey MA, Swedo SE. Sydenham’s chorea clinical and therapeutic update. Adv Exp Med Biol. 1997;418(2):115–20.

    Article  CAS  PubMed  Google Scholar 

  33. BaizabalCarvallo JF, Alonso-Juarez M, Koslowski M. Chorea in systemic lupus erythematosus. J Clin Rheumatol. 2011;17:69–72.

    Article  Google Scholar 

  34. Cervera R, Asherson RA, Font J, et al. Chorea in the antiphospholipid syndrome: clinical, radiologic, and immunologic characteristics of 50 patients from our clinics and the recent literature. Medicine (Baltimore). 1997;76:203–12.

    Article  CAS  Google Scholar 

  35. Angelini L, Zibordi F, Zorzi G, et al. Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Neuropediatrics. 1996;27:149.

    Article  CAS  PubMed  Google Scholar 

  36. Kiechl-Kohlendorfer U, Ellemunter H, Kiechl S. Chorea as the presenting clinical feature of primary antiphospholipid syndrome in childhood. Neuropediatrics. 1999;30:96.

    Article  CAS  PubMed  Google Scholar 

  37. Watanabe T, Onda H. Hemichorea with antiphospholipid antibodies in a patient with lupus nephritis. Pediatr Nephrol. 2004;19:451.

    Article  PubMed  Google Scholar 

  38. Avcin T, Cimaz R, Meroni PL. Recent advances in antiphospholipid antibodies and antiphospholipid syndromes in pediatric populations. Lupus. 2002;11:4.

    Article  CAS  PubMed  Google Scholar 

  39. Ravelli A, Martini A. Antiphospholipid syndrome. Pediatr Clin North Am. 2005;52:469.

    Article  PubMed  Google Scholar 

  40. Dalmau J, Lancaster E, Martinez-Hernandez E, et al. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol. 2011;10:63–74.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Dalmau J, Tuzun E, Wu HY, et al. Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007;61:25–33.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Kieslich M, Errázuriz G, Posselt HG, et al. Brain white-matter lesions in celiac disease: a prospective study of 75 diet-treated patients. Pediatrics. 2001;108:E21.

    Article  CAS  PubMed  Google Scholar 

  43. Zelnik N, Pacht A, Obeid R, et al. Range of neurologic disorders in patients with celiac disease. Pediatrics. 2004;113:1672–6.

    Article  PubMed  Google Scholar 

  44. Dale RC, Merheb V, Pillai S, Wang D, Cantrill L, Murphy TK, Ben-Pazi H, Varadkar S, Aumann TD, Horne MK, Church AJ, Fath T, Brilot F. Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders. Brain. 2012;135:3453–68.

    Article  PubMed  Google Scholar 

  45. Zomorrodi A, Wald ER. Sydenham’s chorea in western Pennsylvania. Pediatrics. 2006;117:e675–9.

    Article  PubMed  Google Scholar 

  46. Walker KG, Lawrenson J, Wilmshurst JM. Neuropsychiatric movement disorders following streptococcal infection. Dev Med Child Neurol. 2005;47:771–5.

    Article  CAS  PubMed  Google Scholar 

  47. Walker KG, Wilmshurst JM. An update on the treatment of Sydenham’s chorea: the evidence for established and evolving interventions. Ther Adv Neurol Disord. 2010;3(5):301–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  48. Cardoso F. Sydenham’s chorea. Curr Treat Options Neurol. 2008;10:230–5.

    Article  PubMed  Google Scholar 

  49. Garvey MA, Snider LA, Leitman SF, Werden R, Swedo SE. Treatment of Sydenham’s chorea with intravenous immunoglobulin, plasma exchange, or prednisone. J Child Neurol. 2005;20:424–9.

    Article  PubMed  Google Scholar 

  50. Dalmau J, et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 2008;7:1091–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Ferdinand P, Mitchell L. AntiNMDA receptor encephalitis. J Clin Cell Immunol. 2012;S10:007. doi:10.4172/2155-9899.S10-007.

    Google Scholar 

  52. Irani SR, Bera K, Waters P, et al. N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes. Brain. 2010;133:1655–67.

    Article  PubMed  PubMed Central  Google Scholar 

  53. Krug P, Schleiermacher G, Michon J, et al. Opsoclonus-myoclonus in children associated or not with neuroblastoma. Eur J Paediatr Neurol. 2010;14:400–9.

    Article  PubMed  Google Scholar 

  54. Tate ED, Allison TJ, Pranzatelli MR, et al. Neuroepidemiologic trends in 105 US cases of pediatric opsoclonus-myoclonus syndrome. J Pediatr Oncol Nurs. 2005;22:8–19.

    Article  PubMed  Google Scholar 

  55. Blaes F. Paraneoplastic brain stem encephalitis. Curr Treat Options Neurol. 2013;15:201–9.

    Article  PubMed  Google Scholar 

  56. Turner MR, Irani SR, Leite MI, Nithi K, Vincent A, Ansorge O. Progressive encephalomyelitis with rigidity and myoclonus: glycine and NMDA receptor antibodies. Neurology. 2011;77(5):439–43.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  57. Damásio J, Leite MI, Coutinho E, Waters P, Woodhall M, Santos MA, Carrilho I, Vincent A. Progressive encephalomyelitis with rigidity and myoclonus: the first pediatric case with glycine receptor antibodies. JAMA Neurol. 2013;70(4):498–501.

    Article  PubMed  Google Scholar 

  58. Swedo SE, Leonard HL, Mittleman BB, et al. Identification of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections by a marker associated with rheumatic fever. Am J Psychiatr. 1997;154:110–2.

    Article  CAS  PubMed  Google Scholar 

  59. Mamoudjy N, Korff C, Maurey H, Blanchard G, Steshenko D, Loiseau-Corvez M-N, Husson B, Brauner R, Tardieu M, Deiva K. Hashimoto’s encephalopathy: identification and long-term outcome in children. Eur J Paediatr Neurol. 2013;17:280e287.

    Article  Google Scholar 

  60. Erol I, Saygi S, Alehan F. Hashimoto’s encephalopathy in children and adolescents. Pediatr Neurol. 2011;45:420e2.

    Article  Google Scholar 

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Authors and Affiliations

  1. Serviço de Neuropediatria, Departamento da criança e Adolescente, Centro Hospitalar do Porto, Porto, Portugal

    Teresa Temudo MD, PhD & Inês Carrilho MD

  2. Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal

    Teresa Temudo MD, PhD

Authors
  1. Teresa Temudo MD, PhD
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  2. Inês Carrilho MD
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Correspondence to Teresa Temudo MD, PhD .

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Editors and Affiliations

  1. Faculty of Medicine, Transilvania University, Brasov, Romania

    Cristian Falup-Pecurariu

  2. Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Lisbon, Portugal

    Joaquim Ferreira

  3. National Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain

    Pablo Martinez-Martin

  4. Centre of Excellence, King’s College London, National Parkinson Foundation Centre of Excellence King’s College, London, United Kingdom

    Kallol Ray Chaudhuri

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Temudo, T., Carrilho, I. (2017). Movement Disorders in Children. In: Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P., Chaudhuri, K. (eds) Movement Disorders Curricula. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1628-9_42

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  • DOI: https://doi.org/10.1007/978-3-7091-1628-9_42

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