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Movement Disorders Curricula pp 103–115Cite as

Clinical Features and Differential Diagnosis of Parkinson’s Disease

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Abstract

Parkinson’s disease (PD) is a clinically defined, progressive neurodegenerative movement disorder with a broad differential diagnosis. Firstly, we will discuss the typical clinical features of PD and its underlying pathology and aetiology. We will then explore the possible differential diagnoses in relation to age at onset, encompassing juvenile/early-onset PD, PD in mid life and PD in the elderly. We will outline the typical features of each differential and useful investigations, which will help to reach the correct diagnosis. Finally, we will provide a practical guide of how to approach a parkinsonian patient in a clinical setting.

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Author information

Authors and Affiliations

  1. Reta Lila Weston Institute of Neurological disease, UCL Institute of Neurology, Queen Square Brain Bank, 1 Wakefield Street, London, WC1N 3BG, UK

    Nadia Magdalinou

  2. Department of Clinical Neuroscience, UCL Institute of Neurology, Upper 3rd Floor, Royal Free Hospital, Rowland Hill Street, London, NW3 2PF, UK

    Huw R. Morris

Authors
  1. Nadia Magdalinou
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  2. Huw R. Morris
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Corresponding author

Correspondence to Huw R. Morris .

Editor information

Editors and Affiliations

  1. Faculty of Medicine, Transilvania University, Brasov, Romania

    Cristian Falup-Pecurariu

  2. Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Lisbon, Portugal

    Joaquim Ferreira

  3. National Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain

    Pablo Martinez-Martin

  4. Centre of Excellence, King’s College London, National Parkinson Foundation Centre of Excellence King’s College, London, United Kingdom

    Kallol Ray Chaudhuri

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Magdalinou, N., Morris, H.R. (2017). Clinical Features and Differential Diagnosis of Parkinson’s Disease. In: Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P., Chaudhuri, K. (eds) Movement Disorders Curricula. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1628-9_11

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  • DOI: https://doi.org/10.1007/978-3-7091-1628-9_11

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  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-1627-2

  • Online ISBN: 978-3-7091-1628-9

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