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Sine Syndromes in Ankylosing Spondylitis

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Abstract

The diagnosis of ankylosing spondylitis is currently based on the proof of sacroiliitis on X-rays. Therefore the term of “ankylosing spondylitis without sacroiliitis” might seem illogical. However, the clinical course of ankylosing spondylitis is (like in other rheumatic inflammatory diseases) highly variable, ranging from mild asymptomatic forms to rapidly progressive ones resulting in ankylosis of the spine or replacement of hip joints, in rhizomelic forms or even in extra-articular manifestations. Thus ankylosing spondylitis can be well “hidden” in this broad spectrum of clinical manifestations. A new concept of axial (and peripheral) spondyloarthritis throws some other light on these issues, which can explain these forms as so-called “pre-radiographic stage of axial spondyloarthritis.”

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Acknowledgement

This paper was supported by a research grant from the Ministry of Health of the Czech Republic No. 000 000 23728

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Correspondence to Jiří Štolfa .

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Štolfa, J. (2014). Sine Syndromes in Ankylosing Spondylitis. In: Rovenský, J., Herold, M., Vašáková, M. (eds) Sine Syndromes in Rheumatology. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1541-1_13

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  • DOI: https://doi.org/10.1007/978-3-7091-1541-1_13

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  • Online ISBN: 978-3-7091-1541-1

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