Abstract
The diagnosis of ankylosing spondylitis is currently based on the proof of sacroiliitis on X-rays. Therefore the term of “ankylosing spondylitis without sacroiliitis” might seem illogical. However, the clinical course of ankylosing spondylitis is (like in other rheumatic inflammatory diseases) highly variable, ranging from mild asymptomatic forms to rapidly progressive ones resulting in ankylosis of the spine or replacement of hip joints, in rhizomelic forms or even in extra-articular manifestations. Thus ankylosing spondylitis can be well “hidden” in this broad spectrum of clinical manifestations. A new concept of axial (and peripheral) spondyloarthritis throws some other light on these issues, which can explain these forms as so-called “pre-radiographic stage of axial spondyloarthritis.”
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Van der Linden SM, Valkenburg HA, Cats A (1984) Evaluation of the diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 27:361–368
Krebs W (1934) Das Roentgenbild des Beckensbei der Bechterewschen Krankheit. Fortschr Roentgenstrahlen 50:537–542
Moll JM, Haslock I, Macrae IF et al (1974) Associations between ankylosing spondylitis, psoriatic arthritis, Reiter’s disease, the intestinal arthropathies and Behçet’s syndrome. Medicine (Baltimore) 53:343–364
Amor B, Dougados M, Mijiyawa M (1990) Critères de classification des spondylarthropathies. Rev Rhum 57:85–89
Dougados M, van der Linden S, Juhlin R et al (1991) The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 34:1218–1227
Kellgren JH, Jeffrey MR, Ball J (1963) The epidemiology of chronic rheumatism, vol I. Blackwell Scientific Publications, Oxford, pp 326–327
Bennett PH, Burch TA (1968) Population studies of the rheumatic diseases. Excerpta Medica Foundation, Amsterdam, pp 456–457
Mau W, Zeidler H, Mau R et al (1988) Clinical features and prognosis of patients with possible ankylosing spondylitis: results of a ten-year follow-up. J Rheumatol 15:1109–1114
Pavelka K et al (2007) Revmatologický ústav Praha. Abstrakta přednášek ze VII. Slapského symposia 12–26.V
Oostveen J, Prevo R, den Boer J et al (1999) Early detection of sacroiliitis on magnetic resonance imaging and subsequent development of sacroiliitis on plain radiography: a prospective, longitudinal study. J Rheumatol 26:1953–1958
Bennet AN, McGonagle D, O’Connor P et al (2008) Severity of baseline magnetic resonance imaging-evident sacroiliitis and HLA-B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years. Arthritis Rheum 58:3413–3418
Rudwaleit M, Landewé R et al (2009) The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68:777–783
Rudwaleit M, Haibel H, Baraliakos X et al (2009) The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort. Arthritis Rheum 60:717–727
Chou CT, Lin KC, Wei JC et al (2005) Study of undifferentiated spondyloarthropathy among first-degree relatives of ankylosing spondylitis probands. Rheumatology (Oxford) 44:662–665
Brandt HC, Spiller I, Song IH et al (2007) Performance of referral recommendations in patients with chronic back pain and suspected axial spondyloarthritis. Ann Rheum Dis 66:1479–1484
Sieper J, Braun J, Rudwaleit M et al (2002) Ankylosing spondylitis: an overview. Ann Rheum Dis 61(Suppl3):iii8–iii18
Nagy SZ, Riler LE, Newby LG (1973) A social epidemiology of back pain in a general population. J Chronic Dis 26:769–779
Lee W, Reveille JD, Davis JC Jr et al (2007) Are there gender differences in severity of ankylosing spondylitis? Results from the PSOAS cohort. Ann Rheum Dis 66:633–638
Linder R, Hoffmann A, Brunner R (2004) Prevalence of the spondyloarthritidies in patients with uveitis. J Rheumatol 31:2226–2229
Balint PV, Kane D, Wilson H et al (2002) Ultrasonography of enthesial insertions in the lower limb in spondyloarthropathy. Ann Rheum Dis 61:905–910
Dekker-Saeys BJ, Meuwissen SG, Van-Der-Berg-Loonen EM (1978) Ankylosing spondylitis and inflammatory bowel disease II. Prevalence of peripheral arthritis, sacroiliitis and ankylosing spondylitis in patients suffering from inflammatory bowel disease. Ann Rheum Dis 37:33–35
Mader R (1999) Atypical clinical presentation of ankylosing spondylitis. Semin Arthritis Rheum 29(3):191–196
Pate D, Huslig EL (1985) Atypical presentation of ankylosing spondylitis: a case study. J Manipulative Physiol Ther 8(2):105–108
Khan MA, van der Linden SM, Kushner I et al (1985) Spondylitic disease without radiographic evidence of sacroiliitis in relatives of HLA B27 positive ankylosing spondylitis patients. Arthritis Rheum 28(1):40–43
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This paper was supported by a research grant from the Ministry of Health of the Czech Republic No. 000 000 23728
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Štolfa, J. (2014). Sine Syndromes in Ankylosing Spondylitis. In: Rovenský, J., Herold, M., Vašáková, M. (eds) Sine Syndromes in Rheumatology. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1541-1_13
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DOI: https://doi.org/10.1007/978-3-7091-1541-1_13
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