Abstract
Vasculitis is defined as an inflammatory cell infiltration and the destruction of blood vessels identified upon histological examination. Cutaneous manifestations may be the first and only manifestation of the disease or be a part of a systemic condition.
Cutaneous vasculitis (CV) affects small (<50 μm) and medium (<50–150 μm) vessels located in the dermis and the hypodermis.
Cutaneous lesions are frequent during the course of many systemic vasculitis. Lesions are often not specific, the most frequent being palpable purpura. Histology is mandatory to confirm the diagnosis of vasculitis to avoid delayed and inappropriate diagnosis that could lead to improper management. Cutaneous histology gives some data that may help to classify the vasculitis without determining precisely its type. A histological examination of all other skin lesions is necessary. The result of the biopsy has to be correlated to direct immunofluorescence data, medical history, physical examination, laboratory, and radiological findings leading to the correct diagnosis and effective treatment.
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References
Kluger N, Francès C. Cutaneous vasculitis and their differential diagnoses. Clin Exp Rheumatol. 2009;27:S124–38.
Carlson JA, Cavaliere LF, Grant-Kels JM. Cutaneous vasculitis: diagnosis and management. Clin Dermatol. 2006;24:414–29.
Carlson JA, Chen KR. Cutaneous vasculitis update: small vessel neutrophilic vasculitis syndromes. Am J Dermatopathol. 2006;28:486–506.
Crowson AN, Mihm Jr MC, Magro CM. Cutaneous vasculitis: a review. J Cutan Pathol. 2003;30:161–73.
Fiorentino DF. Cutaneous vasculitis. J Am Acad Dermatol. 2003;48:311–40.
Carlson JA, Chen KR. Cutaneous pseudovasculitis. Am J Dermatopathol. 2007;29:44–55.
Kluger N, Molinari E, Francès C. Livedo in adults. Ann Dermatol Venereol. 2005;132:710–7.
Hunder GG, Arend WP, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of vasculitis. Introduction. Arthritis Rheum. 1990;33:1065–7.
Jennette JC, Falk RJ, Andrassy K, et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994;37:187–92.
Jennette JC, Falk RJ, Bacon P, et al. 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65:1–11.
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Kluger, N. (2015). Vasculitis. In: Téot, L., Meaume, S., Akita, S., Ennis, W.J., del Marmol, V. (eds) Skin Necrosis. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1241-0_20
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DOI: https://doi.org/10.1007/978-3-7091-1241-0_20
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