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Awake mapping and tumor surgery

  • Chapter
Brain Mapping

Abstract

The first goal of brain tumor surgery is to optimize the extent of resection (EOR) of the lesion. Indeed, maximal resection of glioma, when possible, is currently the first therapeutic option to consider for low-grade gliomas (LGG) (as recommended by the European Guidelines [48]) as well as for high-grade gliomas [49]. In recent series measuring objectively the EOR on repeated postoperative MRI, all of them supported EOR as a statistically significant predictor of overall survival. With WHO grade II gliomas, when no signal abnormality was visible on control MRI, especially on FLAIR-weighted imaging (i.e., the so-called “complete resection”), patients had a significantly longer overall survival compared with patients having any residual abnormality [1,8,19,41,47]. Interestingly, even in cases of incomplete tumor removal, patients with a greater percentage of resection had a significantly longer overall survival.

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Authors
  1. Hugues Duffau
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Editors and Affiliations

  1. Department of Neurosurgery, Hôital Gui de Chauliac CHU Montpellier, Montpellier, France

    Hugues Duffau MD, PhD

  2. Institute of Neuroscience of Montpellier INSERM U1051, Plasticity of Central Nervous System, Human Stem Cells and Glial Tumors, Hôital Saint Eloi CHU Montpellier, Montpellier, France

    Hugues Duffau MD, PhD

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Duffau, H. (2011). Awake mapping and tumor surgery. In: Duffau, H. (eds) Brain Mapping. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0723-2_24

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  • DOI: https://doi.org/10.1007/978-3-7091-0723-2_24

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-0722-5

  • Online ISBN: 978-3-7091-0723-2

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