Abstract
Regardless of 150 years of progression in the neurosciences, neurogenic control of micturation is not fully understood. This is due to the methods of research in correlative neurology, which are not in all instances satisfactory for defining central vegetative control functions, including the mechanisms involved in bladder control:
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A “nucleus” composed of grey matter has to be localized exactly whenever stimulation is intended to uncover its function or ablation is intended to erase function . This is possible only when a nucleus is well deline ate d but not possible in diffusely circumscribed grey masses.
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Fibre degeneration following a lesion is an approach to the interconnections between respect ive nuclei or other circumscribed areas of grey matter. By using this “Wallerian” degeneration, efferent fibre tracts can be traced from a damaged area of origin to the target area as far as a representative proportion of fibres are well myelinated, since myelin breakdown products subserve as “tracers” along the course of degenerating fibres. Clinical case studies are commonly based on th is ‘lesion method’ and Wallerian degeneration.
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Experimental tracer studies and transmitter mapping are further main tools in the general spectrum of neuroscientific research.
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© 2004 Springer-Verlag Wien
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Schmidbauer, M. (2004). Impact of central nervous system alterations to bladder dysfunction in elderly people. In: Plas, E., Pflüger, H., Maier, U., Hübner, W.A. (eds) The Aging Bladder. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0631-0_9
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DOI: https://doi.org/10.1007/978-3-7091-0631-0_9
Publisher Name: Springer, Vienna
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