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Wound healing

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Abstract

The science of wound healing occupies a central role in surgical history and continues to represent a common theme for all surgical subspecialties. As early as 1550 B. C., the Ebers Papyrus of ancient Egypt documents the use of a multitude of natural remedies in wound healing. The Egyptians observed that honey, now known to have hygroscopic and antibacterial properties, proved an effective wound dressing. Mild antiseptics such as frankincense, date-wine, turpentine, and acacia gum also found a place in the Egyptian pharmacopeia. The Egyptians are also credited with the first use of sutures for primary wound closure. In a strikingly early use of 20th century medicine, there is documentation of the application of sour or moldy bread to wounds, now understood to harbor antibiotic-producing fungus [1].

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Authors and Affiliations

  1. Department of Surgery, University of Washington, USA

    David A. Brown

  2. Department of Surgery, Harborview Medical Center, Box 359 796, 325 Ninth Avenue, Seattle, WA, 98 104, USA

    Nicole S. Gibran M.D. (Director, Professor)

  3. Regional Burn Center, University of Washington, USA

    Nicole S. Gibran M.D. (Director, Professor)

  4. UW Burn Center, USA

    Nicole S. Gibran M.D. (Director, Professor)

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  1. David A. Brown
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  2. Nicole S. Gibran M.D.
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Correspondence to Nicole S. Gibran M.D. .

Editor information

Editors and Affiliations

  1. Sunnybrook Health Sciences Centre, Department of Surgery, Division of Plastic Surgery, University of Toronto, Sunnybrook Research Institute, Toronto, ON, Canada

    Marc G. Jeschke M.D., Ph.D.

  2. Plastische, Aesthetische und Rekonstruktive Chirurgie, Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria

    Lars-Peter Kamolz M.D., M.Sc.

  3. Department of Hand and Plastic Surgery and Intensive Care, Linköping University Hospital, Linköping, Sweden

    Folke Sjöberg M.D., Ph.D.

  4. Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

    Folke Sjöberg M.D., Ph.D.

  5. Brooke Army Medical Center, Fort Sam Houston, TX, USA

    Steven E. Wolf M.D.

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Brown, D.A., Gibran, N.S. (2012). Wound healing. In: Jeschke, M.G., Kamolz, LP., Sjöberg, F., Wolf, S.E. (eds) Handbook of Burns. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0348-7_22

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