Disturbances of Iron Metabolism/Disturbances of Erythropoiesis and Hemolysis

Abstract

An impaired iron balance of the body is frequently recognized by the reverse regulation of synthesis of ferritin, the iron storage protein, on the one hand, and of the transferrin receptor, the indicator of iron demand and erythropoietic activity, on the other. This is particularly true if iron deficiency or iron overload is not complicated by additional diseases such as inflammations, tumors or renal failure (Table 2).