Skip to main content

Begleiterkrankungen bei arterieller Hypertonie im Alter

  • Chapter
Altershypertonie und Begleiterkrankungen

Part of the book series: DUV: Medizin ((DUVM))

  • 17 Accesses

Zusammenfassung

Sowohl von der Reaven-Gruppe als auch von anderen Gruppen ist in den letzten Jahren überzeugend dargestellt worden, daß Glukosetoleranzstörungen, Hypercholesterinämie mit vermindertem HDL-Cholesterin, stammbetonte Adipositas und arterielle Hypertonie eine charakteristische Kombination darstellen und möglicherweise bei bis zu 50% der Hypertoniker vorkommen. Die eindeutige familiäre Häufung dieser Kombination sowie die Identifikation einer Insulinresistenz mit nachfolgender Hyperinsulinämie als gemeinsame Ursache führten dazu, daß diese Störungen in der Literatur zu einem Syndrom zusammengefaßt wurden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Castelli WP, Anderson K. A population at risk: prevalence of high cholesterol levels in hypertensive patients in the Framingham study. Am J Med 1986; 80 (suppl 2A): 23–32.

    Article  PubMed  CAS  Google Scholar 

  2. Bonaa KH, Thelle DS. Association between blood pressure and serum lipids in a population. The Tromso study. Circulation 1991; 83, 1305–1314.

    Article  PubMed  CAS  Google Scholar 

  3. Kistler T, Weisser B. Zusammenhänge zwischen Fettstoffwechselstörungen and Hypertonie bei 10892 Heureka-Studienteilnehmern. Schweiz Rundsch Med Prax 1993; 82 (44): 1222–1233.

    PubMed  CAS  Google Scholar 

  4. Ekelund LG. Lowering lipids and the genesis of hypertension. Drugs 1988; 36 (Suppl 3), 21.

    Article  PubMed  Google Scholar 

  5. Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalo J, Dzau VJ. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest 1990; 86 (1): 228–234.

    Article  PubMed  CAS  Google Scholar 

  6. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595–1607.

    Article  PubMed  CAS  Google Scholar 

  7. Weisser B, Locher R, Mengden T, Vetter W. Oxidation of low density lipoprotein enhances its potential to increase intracellular free calcium concentration in vascular smooth muscle cells. Arterioscler Thromb 1992; 12: 231–236.

    Article  PubMed  CAS  Google Scholar 

  8. Sachinidis A, Mengden T, Locher R, Brunner C, Vetter W. Novel cellular activities for low density lipoprotein in vascular smooth muscle cells. Hypertension 1990; 15: 704–711.

    Article  PubMed  CAS  Google Scholar 

  9. Kaplan NM. Problems with the use of diuretics in the treatment of hypertension. Am J Nephrol 1986; 6: 1–5.

    Article  PubMed  CAS  Google Scholar 

  10. Ferranini E, Haffner SM, Stern MP. Essential hypertension: an insulin resistent state. J Cardiovasc Pharmacol 1990; 15 (suppl 5): 18–25.

    Google Scholar 

  11. Fuh MM-T, Shieh S-M, Wu D-A, Chen Y-DI, Reaven GM. Abnormalities of carbohydrate and lipid metabolism in patients with hypertension. Arch Intern Med 1987; 147: 1035–1038.

    Article  PubMed  CAS  Google Scholar 

  12. Weidmann P, Boehlen LM, DE Courten M. Pathogenesis and treatment of hypertension associated with diabetes mellitus. Am Heart J 1993; 125, part 2: 1498.

    Google Scholar 

  13. Pfeffer MA, Braunwald E, Moyé LA, Basta L, Brown EJ, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. N Engl J Med 1992; 327: 669–677.

    Article  PubMed  CAS  Google Scholar 

  14. The Consensus Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure; results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 1987; 316: 1429.

    Article  Google Scholar 

  15. Göbel BO, Dosing R. Was ist gesichert in der Therapie? Herzinsuffizienz. Arcis Verlag: München 1995.

    Google Scholar 

  16. The Solvd Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. N Engl J Med 1991; 325: 293.

    Article  Google Scholar 

  17. Lichteln PR, Hugenholtz PG, Raffenbeul W, Hecker H, JOST S, Deckers JW. Retardation of angiographic progression of coronary artery disease. Results of the International Nifedipine Trial on Antiatherosclerotic Therapy (INTACT). Lancet 1990; 335: 1109–1113.

    Article  Google Scholar 

  18. The ISIS 1 Collaborative Group. Randomized trial of intravenous atenolol among 16.027 cases of suspected acute myocardial infarction: ISIS 1. Lancet 1986; ii: 57–66.

    Google Scholar 

  19. Pfeffer MA, Braunwald E, MoyÉ LA, Basta L, Brown EJ, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. N Engl J Med 1992; 327: 669–677.

    Article  PubMed  CAS  Google Scholar 

  20. Culpepper WS, Sodt PC, Messerli FH. Cardiac anatomy and function in juvenile hypertension. Am J Med 1983; 75 (3A): 57

    Article  PubMed  CAS  Google Scholar 

  21. Kannel WB, Gordon T, Castelli WP. ECG-left ventricular hypertrophy and risk of CHD. The Framingham Study. Ann Intern Med 1970; 72: 813.

    PubMed  CAS  Google Scholar 

  22. Sen S, Tarazi RC, Bumpus FM. Cardiac hypertrophy in spontaneously hypertensive rats. Circ Res 1987; 35: 775.

    Article  Google Scholar 

  23. Fouad-Tarazi FM, Liebson PR. Echocardiographic studies of regression of left ventricular hypertrophy in hypertension. Hypertension 1987; 9: Suppl 2, 65.

    Google Scholar 

  24. Dahlöf B. Regression of left ventricular hypertrophy - are there differences between antihypertensive agents? Cardiology 1992; 81: 307.

    Article  PubMed  Google Scholar 

  25. European Working Group on Critical Leg Ischemia: Second European consensus document on chronic critical leg ischemia. Circulation 1991; 84: IV 1.

    Google Scholar 

  26. Coffman JD. Intermittent claudication and rest pain: Physiologic concepts and therapeutic approaches. Prog Cardiovasc Dis 1979; 22: 59.

    Article  Google Scholar 

  27. Craou MH. Mortality over a period of 10 years in patients with peripheral arterial disease. N Engl J Med 1992; 326: 381.

    Article  Google Scholar 

  28. Sever Hansen K. Postprandial hypotension. Br Med J 1977; 2: 1262.

    Article  Google Scholar 

  29. Caird FI, Andrews GR, Kennedy RD. Effect of posture on blood pressure in the elderly. Br Heart Journal 1973; 35: 527.

    Article  CAS  Google Scholar 

  30. Messerli FH. Osier’s maneuver, pseudohypertension, and true hypertension in the elderly. Am J Med 1986; 80: 906.

    Article  PubMed  CAS  Google Scholar 

  31. Rubin PC Scott PJW, Reid JL. Prazosin disposition in young and elderly subjects. Br J Clin Pharmacol 1981; 12: 401.

    Article  PubMed  CAS  Google Scholar 

  32. Lederle RM. Beeinflussung der Niereninsuffizienz durch antihypertensive Therapie. J Cardiovasc Pharmacol 1992; 20 (suppl 6): 75.

    Google Scholar 

  33. Volhard F. Blutdruck und Niere. Dtsch Med Wochenschr 1992; 16: 425.

    Google Scholar 

  34. Mrocek WJ, Davidov M, Gavrilovich L, Finnerty FA. The value of aggressive therapy in hypertensive patients with azotenia. Circulation 1969; 40: 893.

    Article  Google Scholar 

  35. Reisch C, Mann J, Ritz E. Konversionshemmer in der antihypertensiven Therapie niereninsuffizienter Patienten. Dtsch Med Wochenschr 1987: 112: 1249.

    Article  PubMed  CAS  Google Scholar 

  36. Mann J, Reisch C, Ritz E. Use of angiotensin-converting-enzyme inhibitors for the preservation of kidney function. Nephron 1990; 55 (suppl 1): 38.

    Article  PubMed  Google Scholar 

  37. Baba T, Murabayashi S, Hoyagi K, Takebe K. Renal effects of nicardipine in hypertensive type 2 (non-insulin-dependent) diabetic patients with nephropathy. Diabetologia 1987; 30: 4957.

    Google Scholar 

  38. Hrick DE, Browning PJ, Kopelman R, Goorno WE, Dzau VJ. Captopril-induced functional renal insufficiency in patients with bilateral renal artery stenoses or renal artery stenosis in a solitary kidney. N Engl J Med 1983; 308: 373.

    Article  Google Scholar 

  39. Chrysant SG, Dunn M, Marples D, DE Masters K. Severe reversible azotemia from captopril therapy. Arch Intern Med 1983; 143: 437.

    Article  PubMed  CAS  Google Scholar 

  40. Schwartzstein RS, Fanta CH. Orally administered nifedipine in chronic stable asthma. Am Rev Respir Dis 1986; 134: 262.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Fachmedien Wiesbaden

About this chapter

Cite this chapter

Rudolf, G.A.E., Vetter, H., Weißer, B. (1996). Begleiterkrankungen bei arterieller Hypertonie im Alter. In: Altershypertonie und Begleiterkrankungen. DUV: Medizin. Deutscher Universitätsverlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01653-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-663-01653-3_6

  • Publisher Name: Deutscher Universitätsverlag, Wiesbaden

  • Print ISBN: 978-3-663-01654-0

  • Online ISBN: 978-3-663-01653-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics