Zusammenfassung
Die Entwicklungspsychopharmakologie umfasst alle Fragestellungen der Anwendung von Neuro‑/Psychopharmaka einschließlich der Arzneimittelsicherheit und der Rahmenbedingungen bei einer medikamentösen Behandlung im Kindes- und Jugendalter. In diesem Kapitel werden die Einflüsse der alters- und geschlechtsabhängigen körperlichen und geistigen Reifung auf die Wirkung von Neuro‑/ Psychopharmaka besprochen, und das therapeutische Drug-Monitoring zur Optimierung des Therapieeffektes und als proaktives Instrument zur Förderung der Pharmakovigilanz wird erläutert.
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Quellen und weiterführende Literatur
Egberts K, Fekete S, Häge A et al. (2022) Therapeutisches Drug Monitoring in der Kinder- und Jugendpsychiatrie – Update und Leitfaden für die Praxis. Z Kinder-jugendpsychiatr Psychother. https://doi.org/10.1024/1422-4917/a000845
Gerlach M, Egberts K, Dang S-Y et al. (2016) Therapeutic drug monitoring as a measure of proactive pharmacovigilance in child and adolescent psychiatry. Exp Opin Drug Saf 15:1477–1482
Hiemke C, Bergemann N, Clement HW et al. (2018) Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology – Update 2017. Pharmacopsychiatry 51:9–62
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Gerlach, M., Egberts, K., Taurines, R., Mehler-Wex, C. (2023). Entwicklungspsychopharmakologie. In: Gerlach, M., Mehler-Wex, C., Romanos, M., Walitza, S., Wewetzer, C. (eds) Neuro-/Psychopharmaka im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-65267-1_2
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