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„exercise induced hypoalgesia“ – Integration von sensomotorischer Beanspruchung und Schmerzhemmung

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Schmerztherapie ohne Medikamente

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Zusammenfassung

Die „exercise induced hypoalgesia“ (EIH) ist nur wenig aufgeklärt. Physische Belastungen aktivieren die Endocannabinoide. Ihre Wirkungen sind aber nicht die alleinige Ursache, sondern auch die Plastizität der relevanten Gehirnstrukturen. Dem PFC unterliegt die Top-down-Kontrolle sensorischer und affektiver Vorgänge einschließlich der Schmerzen, und das Belohnungssystem ist einbezogen. Mannigfaltige weitere Veränderungen im Nervengewebe finden statt. Der aktive Muskel mit dem Myokin IL-4 ist ein Faktor der peripheren Mechanismen.

Die EIH benötigt Ermüdung. Sie kann ein Parameter des Ausprägungsgrades sein. Es fehlen belegte Empfehlungen in Abhängigkeit von der Pathogenese und dem Alter. Die anti-nozizeptive Reorganisation des Gehirns benötigt sehr viel Zeit. Bei Chronifizierung ist die EIH variabel. Eine Schmerzverstärkung kann auftreten, weil die Belastbarkeit der Schmerzhemmung überschritten wird. Das Training der nicht vordergründig betroffenen Körperregionen sollte ein wichtiges Element sein.

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Authors and Affiliations

  1. Department für Orthopädie, Unfall- und Wiederherstellungschirurgie, Martin-Luther-Universität Halle-Wittenberg, Halle-Wittenberg, Deutschland

    Wolfgang Laube

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© 2022 Der/die Autor(en), exklusiv lizenziert durch Springer-Verlag GmbH, DE, ein Teil von Springer Nature

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Laube, W. (2022). „exercise induced hypoalgesia“ – Integration von sensomotorischer Beanspruchung und Schmerzhemmung. In: Schmerztherapie ohne Medikamente. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63846-0_9

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  • DOI: https://doi.org/10.1007/978-3-662-63846-0_9

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