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Epidemiologie

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Nicht-alkoholische Fettlebererkrankung

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Zusammenfassung

Die nicht-alkoholische Fettlebererkrankung (NAFLD) stellt die häufigste Lebererkrankung weltweit dar. Wesentliche Risikofaktoren, die zur Entwicklung beitragen, sind eine durch Fehl- und Überernährung hervorgerufene abdominelle Adipositas, Fettstoffwechselstörungen und Insulinresistenz. In metabolischen Risikogruppen mit Diabetes mellitus beträgt die Prävalenz der NAFLD bis zu 80 %. Populationsbasierte, epidemiologische Untersuchungen lassen eine Prävalenz der NAFLD in bis zu einem Drittel der Bevölkerung vermuten. Auch bei Jugendlichen ist eine deutliche Zunahme zu verzeichnen. Neben den externen Risikofaktoren Lebensstil und Ernährung sind intrinsische, genetische Faktoren wesentlich an der Erkrankungsentstehung und dem Verlauf beteiligt. Das Kapitel fasst die verfügbaren Daten zusammen und zeigt detailliert die Bedeutung in Bezug auf extrahepatische Erkrankungen auf.

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Authors and Affiliations

  1. I. Medizinische Klinik, Universitätsmedizin Mainz, Mainz, Deutschland

    Yvonne Huber & Jörn M. Schattenberg

Authors
  1. Yvonne Huber
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  2. Jörn M. Schattenberg
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Correspondence to Jörn M. Schattenberg .

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Editors and Affiliations

  1. Medizinische Klinik u. Poliklinik II, Universititätsklinikum Würzburg, ZIM, Würzburg, Bayern, Deutschland

    Andreas Geier

  2. Medizinische Klinik, Universitätsklinikum Bochum GmbH, Bochum, Deutschland

    Ali Canbay

  3. Klinik für Innere Medizin II, Universitätsklinikum des Saarlandes, Homburg, Saarland, Deutschland

    Frank Lammert

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Huber, Y., Schattenberg, J.M. (2022). Epidemiologie. In: Geier, A., Canbay, A., Lammert, F. (eds) Nicht-alkoholische Fettlebererkrankung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62484-5_1

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  • DOI: https://doi.org/10.1007/978-3-662-62484-5_1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-62483-8

  • Online ISBN: 978-3-662-62484-5

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