Zusammenfassung
Es gibt eine Vielzahl von potenziellen Auslösern für Beschwerden im Bereich des Hüftgelenkes und der Leiste bei Sportlern. Dieses Kapitel gibt eine Übersicht über häufige Ursachen, die zu Beschwerden im vorderen, seitlichen oder hinteren Bereich des Hüftgelenkes führen können. Die Diagnostik- und Therapieprinzipien werden ausgehend von der aktuellen Evidenz vorgestellt.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
als Schmerzprovokations-Test
Literatur
Agricola R, Bessems JH, Ginai AZ, Heijboer MP, van der Heijden RA, Verhaar JA, Weinans H, Waarsing JH (2012) The development of Cam-type deformity in adolescent and young male soccer players. Am J Sports Med 40(5):1099–1106
Agricola R, Heijboer MP, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Waarsing JH (2013a) Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK). Ann Rheum Dis 72(6):918–923
Agricola R, Waarsing JH, Arden NK, Carr AJ, Bierma-Zeinstra SM, Thomas GE, Weinans H, Glyn-Jones S (2013b) Cam impingement of the hip: a risk factor for hip osteoarthritis. Nat Rev Rheumatol 9(10):630–634
Albers IS, Zwerver J, Diercks RL, Dekker JH, Van den Akker-Scheek I (2016) Incidence and prevalence of lower extremity tendinopathy in a Dutch general practice population: a cross sectional study. BMC Musculoskelet Disord 17:16
Anderson K, Strickland SM, Warren R (2001) Hip and groin injuries in athletes. Am J Sports Med 29(4):521–533
Bourne MN, Williams M, Jackson J, Williams KL, Timmins RG, Pizzari T (2019) Preseason hip/groin strength and HAGOS scores are associated with subsequent injury in professional male soccer players. J Orthop Sports Phys Ther 50(5):234–242
Branci S, Thorborg K, Bech BH, Boesen M, Nielsen MB, Holmich P (2015) MRI findings in soccer players with long-standing adductor-related groin pain and asymptomatic controls. Br J Sports Med 49(10):681–691
Brukner P, Khan K (2016) Brukner’s & Khan’s clinical sports medicine. Injuries, 5. Aufl. McGraw-Hill Education Australia, North Ryde
Cacchio A, Rompe JD, Furia JP, Susi P, Santilli V, De Paulis F (2011) Shockwave therapy for the treatment of chronic proximal hamstring tendinopathy in professional athletes. Am J Sports Med 39(1):146–153
Cannon J, Weber AE, Park S, Mayer EN, Powers CM (2020) Pathomechanics underlying femoroacetabular impingement syndrome: a theoretical framework to inform clinical practice. Phys Ther 100(5):788–797, https://doi.org/10.1093/ptj/pzz189
Carro LP, Hernando MF, Cerezal L, Navarro IS, Fernandez AA, Castillo AO (2016) Deep gluteal space problems: piriformis syndrome, ischiofemoral impingement and sciatic nerve release. Muscles Ligaments Tendons J 6(3):384–396
Chu SK, Rho ME (2016) Hamstring injuries in the athlete: diagnosis, treatment, and return to play. Curr Sports Med Rep 15(3):184–190
Clifford C, Paul L, Syme G, Millar NL (2019) Isometric versus isotonic exercise for greater trochanteric pain syndrome: a randomised controlled pilot study. BMJ Open Sport Exerc Med 5(1):e000558
Cook JL, Purdam C (2012) Is compressive load a factor in the development of tendinopathy? Br J Sports Med 46(3):163–168
Davis JA, Stringer MD, Woodley SJ (2012) New insights into the proximal tendons of adductor longus, adductor brevis and gracilis. Br J Sports Med 46:871–876
Degen RM (2019) Proximal hamstring injuries: management of tendinopathy and avulsion injuries. Curr Rev Musculoskelet Med 12(2):138–146
Del Buono A, Papalia R, Khanduja V, Denaro V, Maffulli N (2012) Management of the greater trochanteric pain syndrome: a systematic review. Br Med Bull 102:115–131
Delahunt E, McEntee BL, Kennelly C, Green BS, Coughlan GF (2011) Intrarater reliability of the adductor squeeze test in Gaelic games athletes. J Athletic Training 46:241–245
Falvey EC, Franklyn-Miller A, McCrory PR (2009) The groin triangle: a patho-anatomical approach to the diagnosis of chronic groin pain in athletes. Br J Sports Med 43:213–220
Fearon AM, Scarvell JM, Neeman T, Cook JL, Cormick W, Smith PN (2013) Greater trochanteric pain syndrome: defining the clinical syndrome. Br J Sports Med 47(10):649–653
Feucht MJ, Plath JE, Seppel G, Hinterwimmer S, Imhoff AB, Brucker PU (2015) Gross anatomical and dimensional characteristics of the proximal hamstring origin. Knee Surg Sports Traumatol Arthrosc 23(9):2576–2582
Frank JM, Harris JD, Erickson BJ, Slikker W 3rd, Bush-Joseph CA, Salata MJ, Nho SJ (2015) Prevalence of femoroacetabular impingement imaging findings in asymptomatic volunteers: a systematic review. Arthroscopy 31(6):1199–1204
Franklyn-Miller A, Falvey E, McCrory P (2009) The gluteal triangle: a clinical patho-anatomical approach to the diagnosis of gluteal pain in athletes. Br J Sports Med 43(6):460–466
Franklyn-Miller A, Richter C, King E, Gore S, Moran K, Strike S, Falvey EC (2017) Athletic groin pain (part 2): a prospective cohort study on the biomechanical evaluation of change of direction identifies three clusters of movement patterns. Br J Sports Med 51:460–468
Fredericson M, Moore W, Guillet M, Beaulieu C (2005) High hamstring tendinopathy in runners: meeting the challenges of diagnosis, treatment, and rehabilitation. Phys Sportsmed 33(5):32–43
Freke MD, Kemp J, Svege I, Risberg MA, Semciw A, Crossley KM (2016) Physical impairments in symptomatic femoroacetabular impingement: a systematic review of the evidence. Br J Sports Med 50(19):1180
Garcia AS, Gobetti M, Tatei AY, Falotico GG, Arliani GG, Puertas EB (2019) Prevalence of radiographic signs of femoroacetabular impingement in asymptomatic patients and non-athletes. Rev Bras Ortop 54(1):60–63
Goom TS, Malliaras P, Reiman MP, Purdam CR (2016) Proximal hamstring tendinopathy: clinical aspects of assessment and management. J Orthop Sports Phys Ther 46(6):483–493
Gore SJ, Franklyn-Miller A, Richter C, King E, Falvey EC, Moran K (2020) The effects of rehabilitation on the biomechanics of patients with athletic groin pain. J Biomech 99:109474
Griffin DR, Dickenson EJ, O’Donnell J, Agricola R, Awan T, Beck M, Clohisy JC, Dijkstra HP, Falvey E, Gimpel M, Hinman RS, Holmich P, Kassarjian A, Martin HD, Martin R, Mather RC, Philippon MJ, Reiman MP, Takla A, Thorborg K, Walker S, Weir A, Bennell KL (2016) The Warwick agreement on femoroacetabular impingement syndrome (FAI syndrome): an international consensus statement. Br J Sports Med 50(19):1169–1176
Grimaldi A, Mellor R, Hodges P, Bennell K, Wajswelner H, Vicenzino B (2015) Gluteal tendinopathy: a review of mechanisms, assessment and management. Sports Med 45(8):1107–1119
Heerey JJ, Kemp JL, Mosler AB, Jones DM, Pizzari T, Souza RB, Crossley KM (2018) What is the prevalence of imaging-defined intra-articular hip pathologies in people with and without pain? A systematic review and meta-analysis. Br J Sports Med 52(9):581–593
Hodgson L, Hignett T, Edwards K (2015) Normative adductor squeeze tests scores in rugby. Phys Ther Sport 16:93–97
Hölmich P, Uhrskou P, Ulnits L, Kanstrup IL, Nielsen MB, Bjerg AM, Krogsgaard K (1999) Effectiveness of active physical training as treatment for long-standing adductor-related groin pain in athletes: randomised trial. Lancet 353:439–443
Ishøi L, Sørensen CN, Kaae NM, Jørgensen LB, Hölmich P, Serner A (2016) Large eccentric strength increase using the Copenhagen adduction exercise in football: a randomized controlled trial. Scand J Med Sci Sports 26:1334–1342
Ishøi L, Krommes K, Husted RS, Juhl CB, Thorborg K (2020) Diagnosis, prevention and treatment of common lower extremity muscle injuries in sport – grading the evidence: a statement paper commissioned by the Danish Society of Sports Physical Therapy (DSSF). Br J Sports Med 54(9):528–537. https://doi.org/10.1136/bjsports-2019-101228
Jayaseelan DJ, Moats N, Ricardo CR (2014) Rehabilitation of proximal hamstring tendinopathy utilizing eccentric training, lumbopelvic stabilization, and trigger point dry needling: 2 case reports. J Orthop Sports Phys Ther 44(3):198–205
Kay J, de Sa D, Morrison L, Fejtek E, Simunovic N, Martin HD, Ayeni OR (2017) Surgical management of deep gluteal syndrome causing sciatic nerve entrapment: a systematic review. Arthroscopy 33(12):2263–2278 e2261
Kemp J, Grimaldi A, Heerey J, Jones D, Scholes M, Lawrenson P, Coburn S, King M (2019) Current trends in sport and exercise hip conditions: Intra-articular and extra-articular hip pain, with detailed focus on femoroacetabular impingement (FAI) syndrome. Best Pract Res Clin Rheumatol 33(1):66–87
Khanna V, Caragianis A, Diprimio G, Rakhra K, Beaule PE (2014) Incidence of hip pain in a prospective cohort of asymptomatic volunteers: is the cam deformity a risk factor for hip pain? Am J Sports Med 42(4):793–797
King E, Franklyn-Miller A, Richter C, O’Reilly E, Doolan M, Moran K, Strike S, Falvey É (2018a) Clinical and biomechanical outcomes of rehabilitation targeting intersegmental control in athletic groin pain: prospective cohort of 205 patients. Br J Sports Med 52:1054–1062
King E, Richter C, Franklyn-Miller A, Daniels K, Wadey R, Jackson M, Moran R, Strike S (2018b) Biomechanical but not timed performance asymmetries persist between limbs 9 months after ACL reconstruction during planned and unplanned change of direction. J Biomech 81:93–103
King E, Richter C, Franklyn-Miller A, Daniels K, Wadey R, Moran R, Strike S (2018c) Whole-body biomechanical differences between limbs exist 9 months after ACL reconstruction across jump/landing tasks. Scand J Med Sci Sports 28(12):2567–2578
Kizaki K, Uchida S, Shanmugaraj A, Aquino CC, Duong A, Simunovic N, Martin HD, Ayeni OR (2020) Deep gluteal syndrome is defined as a non-discogenic sciatic nerve disorder with entrapment in the deep gluteal space: a systematic review. Knee Surg Sports Traumatol Arthrosc: Official Journal of the ESSKA 28(10):3354–3364. https://doi.org/10.1007/s00167-020-05966-x PMID: 32246173
Kornaat PR, Van de Velde SK (2014) Bone marrow edema lesions in the professional runner. Am J Sports Med 42:1242–1246
Laslett M, Aprill CN, McDonald B (2006a) Provocation sacroiliac joint tests have validity in the diagnosis of sacroiliac joint pain. Arch Phys Med Rehabil 87(6):874. author reply 874-875
Laslett M, McDonald B, Aprill CN, Tropp H, Oberg B (2006b) Clinical predictors of screening lumbar zygapophyseal joint blocks: development of clinical prediction rules. Spine J 6:370–379
Lempainen L, Sarimo J, Mattila K, Vaittinen S, Orava S (2009) Proximal hamstring tendinopathy: results of surgical management and histopathologic findings. Am J Sports Med 37(4):727–734
Lequesne M (2006) From „periarthritis“ to hip „rotator cuff“ tears. Trochanteric tendinobursitis. Joint Bone Spine 73(4):344–348
Lequesne M, Mathieu P, Vuillemin-Bodaghi V, Bard H, Djian P (2008) Gluteal tendinopathy in refractory greater trochanter pain syndrome: diagnostic value of two clinical tests. Arthritis Rheum 59(2):241–246
Loturco I, Contreras B, Kobal R, Fernandes V, Moura N, Siqueira F, Winckler C, Suchomel T, Pereira LA (2018) Vertically and horizontally directed muscle power exercises: relationships with top-level sprint performance. PLoS One 13(7):e0201475
Lovell G, Galloway H, Hopkins W, Harvey A (2006) Osteitis pubis and assessment of bone marrow edema at the pubic symphysis with MRI in an elite junior male soccer squad. Clin J Sport Med 16:117–122
Maestroni L, Read P, Bishop C, Turner A (2020) Strength and power training in rehabilitation: underpinning principles and practical strategies to return athletes to high performance. Sports Med 50(2):239–252
Martin HD, Khoury A, Schroder R, Palmer IJ (2016) Ischiofemoral impingement and hamstring syndrome as causes of posterior hip pain: where do we go next? Clin Sports Med 35(3):469–486
Mascarenhas VV, Rego P, Dantas P, Morais F, McWilliams J, Collado D, Marques H, Gaspar A, Soldado F, Consciencia JG (2016) Imaging prevalence of femoroacetabular impingement in symptomatic patients, athletes, and asymptomatic individuals: a systematic review. Eur J Radiol 85(1):73–95
McGovern RP, Martin RL, Kivlan BR, Christoforetti JJ (2019) Non-operative management of individuals with non-arthritic hip pain: a literature review. Int J Sports Phys Ther 14(1):135–147
Mellor R, Grimaldi A, Wajswelner H, Hodges P, Abbott JH, Bennell K, Vicenzino B (2016) Exercise and load modification versus corticosteroid injection versus ‚wait and see‘ for persistent gluteus medius/minimus tendinopathy (the LEAP trial): a protocol for a randomised clinical trial. BMC Musculoskelet Disord 17:196
Mellor R, Bennell K, Grimaldi A, Nicolson P, Kasza J, Hodges P, Wajswelner H, Vicenzino B (2018) Education plus exercise versus corticosteroid injection use versus a wait and see approach on global outcome and pain from gluteal tendinopathy: prospective, single blinded, randomised clinical trial. Br J Sports Med 52(22):1464–1472
Michel F, Decavel P, Toussirot E, Tatu L, Aleton E, Monnier G, Garbuio P, Parratte B (2013) Piriformis muscle syndrome: diagnostic criteria and treatment of a monocentric series of 250 patients. Ann Phys Rehabil Med 56(5):371–383
Moreno-Pérez V, Travassos B, Calado A, Gonzalo-Skok O, Del Coso J, Mendez-Villanueva A (2019) Adductor squeeze test and groin injuries in elite football players: a prospective study. Phys Ther Sport 37:54–59
Mosler AB, Agricola R, Weir A, Hölmich P, Crossley KM (2015) Which factors differentiate athletes with hip/groin pain from those without? A systematic review with meta-analysis. Br J Sports Med 49:810–810
Mosler AB, Crossley KM, Thorborg K, Whiteley RJ, Weir A, Serner A, Hölmich P (2017) Hip strength and range of motion: normal values from a professional football league. J Sci Med Sport 20:339–343
Mosler AB, Weir A, Serner A, Agricola R, Eirale C, Farooq A, Bakken A, Thorborg K, Whiteley RJ, Hölmich P, Bahr R, Crossley KM (2018) Musculoskeletal screening tests and bony hip morphology cannot identify male professional soccer players at risk of groin injuries: a 2-year prospective cohort study. Am J Sports Med 46:1294–1305
Neto WK, Soares EG, Vieira TL, Aguiar R, Chola TA, Sampaio VL, Gama EF (2020) Gluteus maximus activation during common strength and hypertrophy exercises: a systematic review. J Sports Sci Med 19(1):195–203
Neumann DA (2010) Kinesiology of the hip: a focus on muscular actions. J Orthop Sports Phys Ther 40(2):82–94
O’Sullivan K, Darlow B, O’Sullivan P, Forster BB, Reiman MP, Weir A (2018) Imaging for hip-related groin pain: don’t be hip-notised by the findings. Br J Sports Med 52(9):551–552
Paajanen H, Hermunen H, Karonen J (2011) Effect of heavy training in contact sports on MRI findings in the pubic region of asymptomatic competitive athletes compared with non-athlete controls. Skelet Radiol 40:89–94
Pollard TC, McNally EG, Wilson DC, Wilson DR, Madler B, Watson M, Gill HS, Carr AJ (2010) Localized cartilage assessment with three-dimensional dGEMRIC in asymptomatic hips with normal morphology and cam deformity. J Bone Joint Surg Am 92(15):2557–2569
Puranen J, Orava S (1988) The hamstring syndrome. A new diagnosis of gluteal sciatic pain. Am J Sports Med 16(5):517–521
Ramazzina I, Bernazzoli B, Braghieri V, Costantino C (2019) Groin pain in athletes and non-interventional rehabilitative treatment: a systematic review. J Sports Med Phys Fitness 59:1001–1010
Retchford T, Crossley K, Grimaldi A, Kemp J, Cowan S (2013) Can local muscles augment stability in the hip? A narrative literature review. J Musculoskelet Neuronal Interact 13:1–12
Rivadulla AR, Gore S, Preatoni E, Richter C (2019) Athletic groin pain patients and healthy athletes demonstrate consistency in their movement strategy selection when performing multiple repetitions of a change of direction test. J Sci Med Sport 23(5):442–447
Robling AG, Burr DB, Turner CH (2001) Recovery periods restore mechanosensitivity to dynamically loaded bone. J Exp Biol 204:3389–3399
Ross JR, Nepple JJ, Philippon MJ, Kelly BT, Larson CM, Bedi A (2014) Effect of changes in pelvic tilt on range of motion to impingement and radiographic parameters of acetabular morphologic characteristics. Am J Sports Med 42(10):2402–2409
Sailly M, Whiteley R, Read JW, Giuffre B, Johnson A, Hölmich P (2015) Pubic apophysitis: a previously undescribed clinical entity of groin pain in athletes. Br J Sports Med 49:828–834
Schilders E, Talbot JC, Robinson P, Dimitrakopoulou A, Gibbon WW, Bismil Q (2009) Adductor-related groin pain in recreational athletes: role of the adductor enthesis, magnetic resonance imaging, and entheseal pubic cleft injections. J Bone Joint Surg Am 91:2455–2460
Schilders E, Bharam S, Golan E, Dimitrakopoulou A, Mitchell A, Spaepen M, Beggs C, Cooke C, Hölmich P (2017) The pyramidalis-anterior pubic ligament-adductor longus complex (PLAC) and its role with adductor injuries: a new anatomical concept. Knee Surg Sports Traumatol Arthrosc 25:3969–3977
Segal NA, Felson DT, Torner JC, Zhu Y, Curtis JR, Niu J, Nevitt MC, Multicenter Osteoarthritis Study G (2007) Greater trochanteric pain syndrome: epidemiology and associated factors. Arch Phys Med Rehabil 88(8):988–992
Serner A, van Eijck CH, Beumer BR, Holmich P, Weir A, de Vos RJ (2015) Study quality on groin injury management remains low: a systematic review on treatment of groin pain in athletes. Br J Sports Med 49(12):813
Serner A, Weir A, Tol JL, Thorborg K, Roemer F, Guermazi A, Hölmich P (2016) Can standardised clinical examination of athletes with acute groin injuries predict the presence and location of MRI findings? Br J Sports Med 50:1541–1547
Speers CJ, Bhogal GS (2017) Greater trochanteric pain syndrome: a review of diagnosis and management in general practice. Br J Gen Pract 67(663):479–480
Stepien K, Smigielski R, Mouton C, Ciszek B, Engelhardt M, Seil R (2019) Anatomy of proximal attachment, course, and innervation of hamstring muscles: a pictorial essay. Knee Surg Sports Traumatol Arthrosc 27(3):673–684
Strauss EJ, Nho SJ, Kelly BT (2010) Greater trochanteric pain syndrome. Sports Med Arthrosc Rev 18(2):113–119
Tak I, Engelaar L, Gouttebarge V, Barendrecht M, Van den Heuvel S, Kerkhoffs G, Langhout R, Stubbe J, Weir A (2017) Is lower hip range of motion a risk factor for groin pain in athletes? A systematic review with clinical applications. Br J Sports Med 51:1611–1621
Taylor R, Vuckovic Z, Mosler A, Agricola R, Otten R, Jacobsen P, Hölmich P, Weir A (2018) Multidisciplinary assessment of 100 athletes with groin pain using the Doha agreement: high prevalence of adductor-related groin pain in conjunction with multiple causes. Clin J Sport Med 28:364–369
Thorborg K, Couppé C, Petersen J, Magnusson SP, Hölmich P (2011) Eccentric hip adduction and abduction strength in elite soccer players and matched controls: a cross-sectional study. Br J Sports Med 45:10–13
Thorborg K, Bandholm T, Zebis M, Andersen LL, Jensen J, Hölmich P (2016) Large strengthening effect of a hip-flexor training programme: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc 24:2346–2352
Thorborg K, Krommes KK, Esteve E, Clausen MB, Bartels EM, Rathleff MS (2017a) Effect of specific exercise-based football injury prevention programmes on the overall injury rate in football: a systematic review and meta-analysis of the FIFA 11 and 11+ programmes. Br J Sports Med 51:562–571
Thorborg K, Rathleff MS, Petersen P, Branci S, Holmich P (2017b) Prevalence and severity of hip and groin pain in sub-elite male football: a cross-sectional cohort study of 695 players. Scand J Med Sci Sports 27(1):107–114
Thorborg K, Reiman MP, Weir A, Kemp JL, Serner A, Mosler AB, Hölmich P (2018) Clinical examination, diagnostic imaging, and testing of athletes with groin pain: an evidence-based approach to effective management. J Orthop Sports Phys Ther 48:239–249
Verrall GM, Hamilton IA, Slavotinek JP, Oakeshott RD, Spriggins AJ, Barnes PG, Fon GT (2005) Hip joint range of motion reduction in sports-related chronic groin injury diagnosed as pubic bone stress injury. J Sci Med Sport 8:77–84
Waldén M, Hägglund M, Ekstrand J (2015) The epidemiology of groin injury in senior football: a systematic review of prospective studies. Br J Sports Med 49:792–797
Weir A, Jansen JACG, van de Port IGL, Van de Sande HBA, Tol JL, Backx FJG (2011) Manual or exercise therapy for long-standing adductor-related groin pain: a randomised controlled clinical trial. Man Ther 16:148–154
Weir A, Brukner P, Delahunt E, Ekstrand J, Griffin D, Khan KM, Lovell G, Meyers WC, Muschaweck U, Orchard J, Paajanen H, Philippon M, Reboul G, Robinson P, Schache AG, Schilders E, Serner A, Silvers H, Thorborg K, Tyler T, Verrall G, de Vos R-J, Vuckovic Z, Hölmich P (2015) Doha agreement meeting on terminology and definitions in groin pain in athletes. Br J Sports Med 49:768–774
White KE (2011) High hamstring tendinopathy in 3 female long distance runners. J Chiropr Med 10(2):93–99
van der Windt DA, Simons E, Riphagen II, Ammendolia C, Verhagen AP, Laslett M, Devillé W, Deyo RA, Bouter LM, de Vet HC, Aertgeerts B (2010) Physical examination for lumbar radiculopathy due to disc herniation in patients with low-back pain. Cochrane Database Syst Rev 138:CD007431
Yousefzadeh A, Shadmehr A, Olyaei GR, Naseri N, Khazaeipour Z (2018) Effect of Holmich protocol exercise therapy on long-standing adductor-related groin pain in athletes: an objective evaluation. BMJ Open Sport Exerc Med 4(1):e000343
Zebis MK, Skotte J, Andersen CH, Mortensen P, Petersen HH, Viskaer TC, Jensen TL, Bencke J, Andersen LL (2013) Kettlebell swing targets semitendinosus and supine leg curl targets biceps femoris: an EMG study with rehabilitation implications. Br J Sports Med 47(18):1192–1198
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Reuter, S. (2020). Hüftgelenk und Leiste. In: Angewandte Sportphysiotherapie - Untere Extremität. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62052-6_2
Download citation
DOI: https://doi.org/10.1007/978-3-662-62052-6_2
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-62051-9
Online ISBN: 978-3-662-62052-6
eBook Packages: Medicine (German Language)