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Biological Augmentation in Rotator Cuff Repair: Cell Therapies

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Massive and Irreparable Rotator Cuff Tears

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Abstract

Mesenchymal stem cells are a “hot topic” in regenerative medicine, and orthopaedics draws fully from this research field in order to improve surgical and conservative treatments. Rotator cuff tear repair is one of the possible applications of stem cells: bone-marrow, adipose, tendon, and muscular tissues have all been studied as available source of multipotential cells. Promising clinical and radiological results emerge from early studies, but long-term follow-ups and randomized controlled studies have been performed before cell therapies would be routinely used in clinical practice.

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Author information

Authors and Affiliations

  1. Laboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy

    Carlo Alberto Stoppani & Sonia Maggi

  2. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Milan, Italy

    Carlo Alberto Stoppani, Sonia Maggi, Alessandra Menon, Chiara Fossati & Pietro Randelli

  3. Laboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy

    Alessandra Menon, Chiara Fossati & Pietro Randelli

  4. Research Center for Adult and Pediatric Rheumatic Diseases (RECAP-RD), Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy

    Alessandra Menon, Chiara Fossati & Pietro Randelli

Authors
  1. Carlo Alberto Stoppani
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  2. Sonia Maggi
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  3. Alessandra Menon
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  4. Chiara Fossati
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  5. Pietro Randelli
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Editor information

Editors and Affiliations

  1. Hospital das Forças Armadas and Hospital da Luz, Porto, Portugal

    Nuno Sampaio Gomes

  2. Department of Traumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia

    Ladislav Kovačič

  3. ATOS Klinik München, Deutsches Schulterzentrum, München, Bayern, Germany

    Frank Martetschläger

  4. Department of Orthopaedics, University of Brescia, Brescia, Italy

    Giuseppe Milano

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Stoppani, C.A., Maggi, S., Menon, A., Fossati, C., Randelli, P. (2020). Biological Augmentation in Rotator Cuff Repair: Cell Therapies. In: Sampaio Gomes, N., Kovačič, L., Martetschläger, F., Milano, G. (eds) Massive and Irreparable Rotator Cuff Tears. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-61162-3_6

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  • DOI: https://doi.org/10.1007/978-3-662-61162-3_6

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-61161-6

  • Online ISBN: 978-3-662-61162-3

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