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Biological Augmentation in Rotator Cuff Repair: Growth Factors

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Massive and Irreparable Rotator Cuff Tears

Abstract

Growth factors such as the use of platelet-rich plasma-containing growth factors, e.g., IL-1 and IL-6 or TNF-alpha, have been extensively studied but their clinical benefits could not be found. However, currently there are upcoming studies on loading growth factors on matrices with promising results in animal models. To date, the easiest and most cost-effective enhancement in rotator cuff repairs is microfracturing of the humeral head to promote bone marrow stimulation.

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Author information

Authors and Affiliations

  1. ARTHRO Medics, Shoulder and Elbow Center, Basel, Switzerland

    Claudio Rosso

  2. University of Basel, Basel, Switzerland

    Claudio Rosso

  3. Alphaclinic Zurich, Zurich, Switzerland

    Patrick Vavken

  4. Boston Children’s Hospital, Harvard Medical School, Boston, USA

    Patrick Vavken

Authors
  1. Claudio Rosso
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  2. Patrick Vavken
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Corresponding author

Correspondence to Claudio Rosso .

Editor information

Editors and Affiliations

  1. Hospital das Forças Armadas and Hospital da Luz, Porto, Portugal

    Nuno Sampaio Gomes

  2. Department of Traumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia

    Ladislav Kovačič

  3. ATOS Klinik München, Deutsches Schulterzentrum, München, Bayern, Germany

    Frank Martetschläger

  4. Department of Orthopaedics, University of Brescia, Brescia, Italy

    Giuseppe Milano

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Rosso, C., Vavken, P. (2020). Biological Augmentation in Rotator Cuff Repair: Growth Factors. In: Sampaio Gomes, N., Kovačič, L., Martetschläger, F., Milano, G. (eds) Massive and Irreparable Rotator Cuff Tears. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-61162-3_5

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  • DOI: https://doi.org/10.1007/978-3-662-61162-3_5

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-61161-6

  • Online ISBN: 978-3-662-61162-3

  • eBook Packages: MedicineMedicine (R0)

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