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Klassifikation und Diagnostik inklusive Früherkennung

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S3-Leitlinie zur Diagnostik und Therapie Bipolarer Störungen

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Zusammenfassung

Die korrekte Diagnosestellung ist die Grundvoraussetzung für eine adäquate Behandlung des Patienten und somit für die Aufrechterhaltung eines höchstmöglichen Funktionsvermögens im beruflichen und sozialen Leben. Je eher die Diagnose feststeht, desto schneller kann die Information und Beratung des Patienten und, wenn gewünscht, seiner Bezugspersonen erfolgen sowie eine adäquate Behandlung beginnen. Die Diagnostik Bipolarer Störungen ist nicht immer einfach, u. a. durch die im Erkrankungsverlauf häufig als erste Episode auftretende Depression und die oftmals fehlende Beeinträchtigung des Patienten durch hypomanische Symptome.

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Literatur

  • Altman EG, Hedeker D, Peterson JL, Davis JM (1997) The Altman self-rating mania scale. Biol Psychiatry 42(10):948–955

    Article  CAS  Google Scholar 

  • American Psychiatric Association (2018) Diagnostisches und Statistisches Manual Psychischer Störungen DSM-5, 2. korrigierte Aufl. Hogrefe

    Google Scholar 

  • Angst J, Gamma A (2002) A new bipolar spectrum concept: a brief review. Bipolar Disord 4(Suppl. 1):11–14

    Article  Google Scholar 

  • Angst J, Adolfsson R, Benazzi F, Gamma A, Hantouche E, Meyer TD, Skeppar P, Vieta E, Scott J (2005a) The HCL-32: towards a self-assessment tool for hypomanic symptoms in outpatients. J Affect Disord 88(2):217–233. https://doi.org/10.1016/j.jad.2005.05.011

    Article  Google Scholar 

  • Antonucci R, Cuzzolin L, Manconi A, Cherchi C, Oggiano AM, Locci C (2018) Maternal carbamazepine therapy and unusual adverse effects in a breastfed infant. Breastfeed Med 13(2):155–157. https://doi.org/10.1089/bfm.2017.0235

    Article  Google Scholar 

  • Bauer IE, Keefe RSE, Sanches M, Suchting R, Green CE, Soares JC (2015) Evaluation of cognitive function in bipolar disorder using the brief assessment of cognition in affective disorders (BAC-A). J Psychiatr Res 60:81–86

    Article  Google Scholar 

  • Bauer M, Grof P, Gyulai L, Rasgon N, Glenn T, Whybrow PC (2004) Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder 1. Bipolar Disord 6(1):67–74

    Article  Google Scholar 

  • Bauer M, Rasgon N, Grof P, Gyulai L, Glenn T, Whybrow PC (2005b) Does the use of an automated tool for self-reporting mood by patients with bipolar disorder bias the collected data? 1. MedGenMed 7(3):21

    Google Scholar 

  • Bauer M, Juckel G, Correll CU, Leopold K, Pfennig A (2008b) Diagnosis and treatment in the early illness phase of bipolar disorders. Eur Arch Psychiatry Clin Neurosci 258(Suppl. 5):50–54. https://doi.org/10.1007/s00406-008-5009-z

    Article  Google Scholar 

  • Bauer MS, Critschristoph P, Ball WA, Dewees E, Mcallister T, Alahi P, Cacciola J, Whybrow PC (1991) Independent assessment of manic and depressive symptoms by self-rating – scale characteristics and implications for the study of mania. Arch Gen Psychiatry 48(9):807–812

    Article  CAS  Google Scholar 

  • Bech P, Rafaelsen OJ (1980) The use of rating-scales exemplified by a comparison of the Hamilton and the Bech-Rafaelsen Melancholia Scale. Acta Psychiatr Scand 62(S285):128–132

    Article  Google Scholar 

  • Bech P, Rafaelsen OJ, Kramp P, Bolwig TG (1978) Mania rating-scale – scale construction and inter-observer agreement. Neuropharmacology 17(6):430–431

    Article  CAS  Google Scholar 

  • Bechdolf A, Ratheesh A, Cotton SM, Nelson B, Chanen AM, Betts J, Bingmann T, Yung AR, Berk M, McGorry PD (2014) The predictive validity of bipolar at-risk (prodromal) criteria in help-seeking adolescents and young adults: a prospective study. Bipolar Disord 16(5):493–504. https://doi.org/10.1111/bdi.12205

    Article  Google Scholar 

  • Beck AT, Steer RA (1987) Beck depression inventory – manual. The Psychological Association, San Antonio

    Google Scholar 

  • Beck AT, Erbaugh J, Ward CH, Mock J, Mendelsohn M (1961) An inventory for measuring depression. Arch Gen Psychiatry 4(6):561–571

    Article  CAS  Google Scholar 

  • Beck AT, Steer RA, Brown GK (1996) Manual for the Beck depression inventory, Bd 2, 2. Aufl. The Psychological Corporation, San Antonio

    Google Scholar 

  • Benninghoff J, Brieger P (2018) Bipolare affektive Störungen im höheren Lebensalter. Z Gerontol Geriatr 51(7):750–756

    Article  Google Scholar 

  • Berk M, Hallam K, Lucas N, Hasty M, Mcneil CA, Conus P, Kader L, McGorry PD (2007) Early intervention in bipolar disorders: opportunities and pitfalls. Med J Aust 187(7):11–14

    Google Scholar 

  • Bernhard B, Meyer TD (2011) Bipolare Störungen. In: Margraf J (Hrsg) Lehrbuch der Verhaltenstherapie: Band 4: Materialien für die Psychotherapie. Springer,

    Google Scholar 

  • Bromley RL, Calderbank R, Cheyne CP, Rooney C, Trayner P, Clayton-Smith J, García-Fiñana M, Irwin B, Morrow JI, Shallcross R, Baker GA (2016) Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate. Neurology 87(18):1943–1953. https://doi.org/10.1212/WNL.0000000000003157

    Article  CAS  Google Scholar 

  • Carney CP, Jones LE (2006) Medical comorbidity in women and men with bipolar disorders: a population-based controlled study 1. Psychosom Med 68(5):684–691. https://doi.org/10.1097/01.psy.0000237316.09601.88

    Article  Google Scholar 

  • Collegium Internationale Psychiatriae Scalarum (2005) Internationale Skalen für Psychiatrie. Beltz Test GmbH, Göttingen

    Google Scholar 

  • Colom F, Vieta E (2009) The road to DSM-V bipolar disorder episode and course specifiers. Psychopathology 42(4):209–218. https://doi.org/10.1159/000218518

    Article  CAS  Google Scholar 

  • Conus P, Ward J, Hallam KT, Lucas N, Macneil C, McGorry PD, Berk M (2008) The proximal prodrome to first episode mania – a new target for early intervention. Bipolar Disord 10(5):555–565

    Article  Google Scholar 

  • Correll CU, Penzner JB, Frederickson AM, Richter JJ, Auther AM, Smith CW, Kane JM, Cornblatt BA (2007a) Differentiation in the preonset phases of schizophrenia and mood disorders: evidence in support of a bipolar mania prodrome. Schizophr Bull 33(3):703–714. https://doi.org/10.1093/schbul/sbm028

    Article  Google Scholar 

  • Correll CU, Penzner JB, Lencz T, Auther A, Smith CW, Malhotra AK, Kane JM, Cornblatt BA (2007b) Early identification and high-risk strategies for bipolar disorder. Bipolar Disord 9(4):324–338

    Article  Google Scholar 

  • Correll CU, Olvet DM, Auther AM, Hauser M, Kishimoto T, Carrión RE, Snyder S, Cornblatt BA (2014) The Bipolar Prodrome Symptom Interview and Scale-Prospective (BPSS-P): description and validation in a psychiatric sample and healthy controls. Bipolar Disord 16(5):505–522. https://doi.org/10.1111/bdi.12209

    Article  Google Scholar 

  • Crettenand M, Rossetti AO, Buclin T, Winterfeld U (2018) Antiepileptika in der Stillzeit. Wie beraten wir die Mütter? (Use of antiepileptic drugs during breastfeeding : What do we tell the mother?). Nervenarzt 89(8):913–921. https://doi.org/10.1007/s00115-018-0496-2

    Article  CAS  Google Scholar 

  • Crump C, Sundquist K, Winkleby MA, Sundquist J (2013) Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. JAMA psychiatry 70(9):931–939. https://doi.org/10.1001/jamapsychiatry.2013.1394

    Article  Google Scholar 

  • DeHert M, Dekker JM, Wood D, Kahl KG, Holt RI, Moller HJ (2009) Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC) 1. Eur Psychiatry 24(6):412–424. https://doi.org/10.1016/j.eurpsy.2009.01.005

    Article  CAS  Google Scholar 

  • Denicoff KD, Ali SO, Sollinger AB, Smith-Jackson EE, Leverich GS, Post RM (2002) Utility of the daily prospective National Institute of Mental Health Life-Chart Method (NIMH-LCM-p) ratings in clinical trials of bipolar disorder. Depress Anxiety 15(1):1–9

    Article  Google Scholar 

  • DGPPN (2009) Leitliniengruppe Unipolare Depression (2009) S3-Leitlinie/Nationale VersorgungsLeitlinie Unipolare Depression-Langfassung. DGPPN, ŽZQ, AWMF, Berlin/Düsseldorf

    Google Scholar 

  • DGPPN (2015) S3-Leitlinie/Nationale Versorgungsleitlinie: Unipolare Depression. Langfassung, 2. Aufl. Version 5, AWMF-Register-Nr.: nvl-005

    Google Scholar 

  • Duffy A, Alda M, Milin R, Grof P (2007a) A consecutive series of treated affected offspring of parents with bipolar disorder: is response associated with the clinical profile? Can J Psychiatry Rev Can Psychiatr 52(6):369–376. https://doi.org/10.1177/070674370705200606

    Article  Google Scholar 

  • Findling RL, Frazier TW, Youngstrom EA, McNamara NK, Stansbrey RJ, Gracious BL, Reed MD, Demeter CA, Calabrese JR (2007) Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorder. J Clin Psychiatry 68(5):781–788

    Article  CAS  Google Scholar 

  • Papachristou E, et al. (2013) Child Behavior Checklist-Mania Scale (CBCL-MS): development and evaluation of a population-based screening scale for bipolar disorder. PLoS One 8(8). e69459

    Google Scholar 

  • First MB, Spitzer RL, Robert L, Gibbon M, Williams JB (1996) Structured clinical interview for DSM-IV axis I disorders, clinician version (SCID-CV). American Psychiatric Press, Inc, Washington, DC

    Google Scholar 

  • Gauggel S, Birkner B (1999) Validity and reliability of a German version of the Geriatric Depression Scale (GDS). Z Klinisch Psychol-Forschung Praxis 28(1):18–27

    Article  Google Scholar 

  • Geller B, Cooper TB, Sun K, Zimerman B, Frazier J, Williams M, Heath J (1998) Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. J Am Acad Child Adolesc Psychiatry 37(2):171–178

    Article  CAS  Google Scholar 

  • George EL, Miklowitz DJ, Richards JA, Simoneau TL, Taylor DO (2003) The comorbidity of bipolar disorder and axis II personality disorders: prevalence and clinical correlates. Bipolar Disord 5(2):115–122

    Article  Google Scholar 

  • Ghaemi SN, Miller CJ, Berv DA, Klugman J, Rosenquist KJ, Pies RW (2005) Sensitivity and specificity of a new bipolar spectrum diagnostic scale. J Affect Disord 84(2–3):273–277. https://doi.org/10.1016/S0165-0327(03)00196-4

    Article  Google Scholar 

  • Ghaemi SN, Bauer M, Cassidy F, Malhi GS, Mitchell P, Phelps J, Vieta E, Youngstrom E (2008a) Diagnostic guidelines for bipolar disorder: a summary of the International society for bipolar disorders diagnostic guidelines task force report. Bipolar Disord 10(1 Pt 2):117–128

    Article  Google Scholar 

  • Goldstein TR, Fersch-Podrat R, Axelson DA, Gilbert A, Hlastala SA, Birmaher B, Frank E (2014) Early intervention for adolescents at high risk for the development of bipolar disorder: pilot study of Interpersonal and Social Rhythm Therapy (IPSRT). Psychotherapy (Chicago, Ill.) 51(1):180–189. https://doi.org/10.1037/a0034396

  • van Gülick-Bailer M, Maurer K, Häfner H (1995) Schedules for Clinical Assessment in Neuropsychiatry Deutsche Ausgabe (SCAN). Huber, Göttingen

    Google Scholar 

  • Habermann F, Fritzsche J, Fuhlbrück F, Wacker E, Allignol A, Weber-Schoendorfer C, Meister R, Schaefer C (2013) Atypical antipsychotic drugs and pregnancy outcome. A prospective, cohort study. J Clin Psychopharmacol 33(4):453–462. https://doi.org/10.1097/JCP.0b013e318295fe12

    Article  CAS  Google Scholar 

  • Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23(1):56–62

    Article  CAS  Google Scholar 

  • Hauser M, Pfennig A, Ozgurdal S, Heinz A, Bauer M, Juckel G (2007) Early recognition of bipolar disorder. Eur Psychiatry 22(2):92–98. https://doi.org/10.1016/j.eurpsy.2006.08.003

    Article  Google Scholar 

  • Hautzinger M, Bailer M (1999) Das Inventar depressiver Symptome (IDS). Unveröffentlichter Testbericht

    Google Scholar 

  • Hautzinger M, Meyer TD (2002) Diagnostik affektiver Störungen (Kompendium Psychologische Diagnostik, Band 3). Hogrefe, Göttingen

    Google Scholar 

  • Hautzinger M, Keller F, Kühner C (2006) Beck depressions-inventar (BDI-II). Revision. Harcourt Test Services, Frankfurt/Main

    Google Scholar 

  • Hautzinger M, Bailer M, Hofmeister D, Keller F (2012) Allgemeine Depressions-Skala (ADS). 2., überarbeitete und neu normierte Aufl. Hogrefe Verlag, Göttingen

    Google Scholar 

  • Hergueta T, Weiller E (2013) Evaluating depressive symptoms in hypomanic and manic episodes using a structured diagnostic tool: validation of a new Mini International Neuropsychiatric Interview (M.I.N.I.) module for the DSM-5 ‚With Mixed Features‘ specifier. Int J Bipolar Disord 1:21. https://doi.org/10.1186/2194-7511-1-21

  • Herrmann-Lingen C, Buss U, Snaith RP (2005) HADS-D-Hospital Anxiety and Depression Scale- Deutsche Version: Deutsche Adaption der Hospital Anxiety and Depression Scale (HADS) von R.P. Snaith und A.S. Zigmond, vol 2. Verlag Hans Huber, Bern

    Google Scholar 

  • Hiller W, Zaudig M, Mombour W (1995) ICDL. Internationale Diagnosen Checklisten für ICD-10 und DSM-IV (Manual und 32 Checklisten nach ICD-10 als Bestandteil des Gesamtpakets der ICD-10-Checklisten der WHO). Huber, Bern

    Google Scholar 

  • Hirschfeld RMA, Data L, Calabrese JR, Keck PE, Lewis L, SL ME, Post RM, Rapport DJ, Russell JM, Sachs GS, Zajecka J (2000) Development and validation of a screening instrument for bipolar spectrum disorder: the mood disorder questionnaire. Am J Psychiatr 157(11):1873–1875

    Article  CAS  Google Scholar 

  • Hudson JI, Hiripi E, Pope HGJ, Kessler RC (2007) The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication 10. Biol Psychiatry 61(3):348–358. https://doi.org/10.1016/j.biopsych.2006.03.040

    Article  Google Scholar 

  • Keefe RS, Fox KH, Davis VG, Kennel C, Walker TM, Burdick KE, Harvey PD (2014) The Brief Assessment of Cognition In Affective Disorders (BAC-A): performance of patients with bipolar depression and healthy controls. J Affect Disord 166:86–92. https://doi.org/10.1016/j.jad.2014.05.002

    Article  Google Scholar 

  • Khan A, Faucett J, Morrison S, Brown WA (2013) Comparative mortality risk in adult patients with schizophrenia, depression, bipolar disorder, anxiety disorders, and attention-deficit/hyperactivity disorder participating in psychopharmacology clinical trials. JAMA psychiatry 70(10):1091–1099. https://doi.org/10.1001/jamapsychiatry.2013.149

    Article  Google Scholar 

  • Klosterkötter J, Maier W (eds) (2017) Handbuch Präventive Psychiatrie. Forschung – Lehre – Versorgung: mit 29 Abbildungen und 34 Tabellen. Schattauer, Stuttgart

    Google Scholar 

  • Krüger S, Bräunig P, Shugar G (1997) Manie-Selbstbeurteilungsskala (MMS). – Deutsche Bearbeitung des Self-Report Manic Inventory. Beltz, Göttingen

    Google Scholar 

  • Kühner C (1997) FDD-DSM-IV Fragebogen zur Depressionsdiagnostik nach DSM-IV. Hogrefe, Göttingen

    Google Scholar 

  • Leopold K, Ritter P, Correll CU, Marx C, Ozgurdal S, Juckel G, Bauer M, Pfennig A (2011) Risk constellations prior to the development of bipolar disorders: rationale of a new risk assessment tool. J Affect Disord 136:1000–1010. https://doi.org/10.1016/j.jad.2011.06.043

    Article  Google Scholar 

  • Lieberman DZ, Kelly TF, Douglas L, Goodwin FK (2010) A randomized comparison of online and paper mood charts for people with bipolar disorder. J Affect Disord 124(1–2):85–89. https://doi.org/10.1016/j.jad.2009.10.019

    Article  Google Scholar 

  • Löwe B,Spitzer RL, Zipfel S, Herzog W (2002) Gesundheitsfragebogen für Patienten (PHQ D). Komplettversion und Kurzform. Testmappe mit Manual, Fragebögen, Schablonen. Pfizer, Karlsruhe

    Google Scholar 

  • Mantere O, Isometsa E, Ketokivi M, Kiviruusu O, Suominen K, Valtonen HM, Arvilommi P, Leppamaki S (2010) A prospective latent analyses study of psychiatric comorbidity of DSM-IV bipolar I and II disorders. Bipolar Disord 12(3):271–284. https://doi.org/10.1111/j.1399-5618.2010.00810.x

    Article  Google Scholar 

  • Margraf J (1994) Diagnostisches Kurz-Interview bei psychischen Störungen: Mini-DIPS. Springer, Berlin/Heidelberg

    Book  Google Scholar 

  • Matthews AM, Huckans MS, Blackwell AD, Hauser P (2008) Hepatitis C testing and infection rates in bipolar patients with and without comorbid substance use disorders. Bipolar Disord 10(2):266–270. https://doi.org/10.1111/j.1399-5618.2007.00472.x

    Article  Google Scholar 

  • McIntyre RS, Konarski JZ, Misener VL, Kennedy SH (2005b) Bipolar disorder and diabetes mellitus: epidemiology, etiology, and treatment implications. Ann Clin Psychiatry 17(2):83–93

    Article  Google Scholar 

  • McIntyre RS, Nguyen HT, Soczynska JK, Lourenco MT, Woldeyohannes HO, Konarski JZ (2008) Medical and substance-related comorbidity in bipolar disorder: translational research and treatment opportunities. Dialogues Clin Neurosci 10(2):203–213

    Google Scholar 

  • Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M, Kessler RC (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 64(5):543–552. https://doi.org/10.1001/archpsyc.64.5.543

    Article  Google Scholar 

  • Meyer T, Bernhard B, Fuhr K, Gerber S, Schaerer L et al (2011) The hypomania checklist-32 and the mood disorder questionnaire as screening tools – going beyond samples of purely mood-disordered patients. J Affect Disord 128(3):291–298

    Article  Google Scholar 

  • Meyer TD, Hautzinger M (2001) Allgemeine Depressions-Skala (ADS) – Normierung an Minderj„hrigen und Erweiterung zur Erfassung manischer Symptome (ADMS). Diagnostica 47:208–215

    Article  Google Scholar 

  • Meyer TD, Hautzinger M (2004) Manisch Depressive Störung. Kognitiv-verhaltenstherapeutisches Behandlungsmanual. Beltz, Weinheim

    Google Scholar 

  • Meyer TD, Schrader J, Ridley M, Lex C (2014) The Hypomania Checklist (HCL) – systematic review of its properties to screen for bipolar disorders. Compr Psychiatry 55(5):1310–1321

    Article  Google Scholar 

  • Miklowitz DJ, Chang KD, Taylor DO, George EL, Singh MK, Schneck CD, Dickinson LM, Howe ME, Garber J (2011) Early psychosocial intervention for youth at risk for bipolar I or II disorder: a one-year treatment development trial. Bipolar Disord 13(1):67–75. https://doi.org/10.1111/j.1399-5618.2011.00890.x

    Article  Google Scholar 

  • Miklowitz DJ, Schneck CD, Singh MK, Taylor DO, George EL, Cosgrove VE, Howe ME, Dickinson LM, Garber J, Chang KD (2013) Early intervention for symptomatic youth at risk for bipolar disorder: a randomized trial of family-focused therapy. J Am Acad Child Adolesc Psychiatry 52(2):121–131. https://doi.org/10.1016/j.jaac.2012.10.007

    Article  Google Scholar 

  • Montgomery SA, Asberg M (1979) New depression scale designed to be sensitive to change. Br J Psychiatry 134(4):382–389

    Article  CAS  Google Scholar 

  • Morin C, Chevalier I (2017) Severe hypernatremic dehydration and lower limb gangrene in an infant exposed to lamotrigine, aripiprazole, and sertraline in breast milk. Breastfeed Med 12(6):377–380. https://doi.org/10.1089/bfm.2017.0031

    Article  Google Scholar 

  • Morosini PL, Magliano L, Brambilla L, Ugolini S, Pioli R (2000) Development, reliability and acceptability of a new version of the DSM-IV Social and Occupational Functioning Assessment Scale (SOFAS) to assess routine social functioning. Acta Psychiatr Scand 101(4):323–329

    Article  CAS  Google Scholar 

  • Mühlbacher M, Egger C, Kaplan P, Simhandl C, Grunze H, Geretsegger C, Whitworth A, Stuppäck C (2011) Relabilität und Übereinstimmungsvalidität der deutschen Version der Young Mania Rating Scale (YMRS-D) (Reliability and concordance validity of a German version of the Young Mania Rating Scale (YMRS-D)). Neuropsychiatr Klinik Diagnostik Ther Rehab Organ Gesellschaft Osterreichischer Nervenarzte Psychiater 25(1):16–25

    Google Scholar 

  • Myrick H, Cluver J, Swavely S, Peters H (2004) Diagnosis and treatment of co-occurring affective disorders and substance use disorders. Psychiatr Clin North Am 27(4):649–659. https://doi.org/10.1016/j.psc.2004.06.003

    Article  Google Scholar 

  • Nadkarni RB, Fristad MA (2010) Clinical course of children with a depressive spectrum disorder and transient manic symptoms. Bipolar Disord 12(5):494–503. https://doi.org/10.1111/j.1399-5618.2010.00847.x

    Article  Google Scholar 

  • Newcomer JW (2006) Medical risk in patients with bipolar disorder and schizophrenia. J Clin Psychiatry 67(11):e16

    Article  Google Scholar 

  • Ozgurdal S, van Haren E, Hauser M, Strohle A, Bauer M, Assion H-J, Juckel G (2009) Early mood swings as symptoms of the bipolar prodrome: preliminary results of a retrospective analysis. Psychopathology 42(5):337–342. https://doi.org/10.1159/000232977

    Article  Google Scholar 

  • Park Y, Hernandez-Diaz S, Bateman BT, Cohen JM, Desai RJ, Patorno E, Glynn RJ, Cohen LS, Mogun H, Huybrechts KF (2018) Continuation of atypical antipsychotic medication during early pregnancy and the risk of gestational diabetes. Am J Psychiatry 175(6):564–574. https://doi.org/10.1176/appi.ajp.2018.17040393

    Article  Google Scholar 

  • Paulus W, Sterzik K, Stoz F (2005) Atypical antipsychitic agents in early pregnancy. Rep Toxicol (20):477–478

    Google Scholar 

  • Pfennig A, Correll CU, Marx C, Rottmann-Wolf M, Meyer TD, Bauer M, Leopold K (2014a) Psychotherapeutic interventions in individuals at risk of developing bipolar disorder: a systematic review. Early Interv Psychiatry 8(1):3–11. https://doi.org/10.1111/eip.12082

    Article  Google Scholar 

  • Pfennig A, Leopold K, Bechdolf A, Correll CU, Holtmann M, Lambert M, Marx C, Meyer TD, Pfeiffer S, Reif A, Rottmann-Wolf M, Schmitt NM, Stamm T, Juckel G, Bauer M (2014b) Early specific cognitive-behavioural psychotherapy in subjects at high risk for bipolar disorders: study protocol for a randomised controlled trial. Trials 15:161. https://doi.org/10.1186/1745-6215-15-161

    Article  Google Scholar 

  • Pfennig A, Connell J, Ritter P, Ritter D, Severus E, Meyer TD, Hautzinger M, Wolff J, Godemann F, Reif A, Bauer M (2017) Leitliniengerechte psychiatrisch-psychotherapeutische Behandlung bei bipolaren Störungen : Welche Ressourcen werden dafür benötigt? Nervenarzt 88(3):222–233

    Article  CAS  Google Scholar 

  • Pfennig A, Leopold K, Ritter P, Bohme A, Severus E, Bauer M (2017a) Longitudinal changes in the antecedent and early manifest course of bipolar disorder-A narrative review of prospective studies. Aust N Z J Psychiatry 51(5):509–523. https://doi.org/10.1177/0004867417700730

    Article  Google Scholar 

  • Pierre JM (2005) Extrapyramidal symptoms with atypical antipsychotics. Incidence, prevention and management. Drug Saf 28(3):191–208

    Article  CAS  Google Scholar 

  • Radloff LS (1977) The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1:385–401

    Article  Google Scholar 

  • Richter P, Saß H, Sauer H (1990) On the validity of the German version of the comprehensive psychopathological rating scale. Eur Arch Psychiatry Clin Nuerosci 240(1):48–53. https://doi.org/10.1007/BF02190093

    Article  CAS  Google Scholar 

  • Ritter PS, Bermpohl F, Gruber O, Hautzinger M, Jansen A, Juckel G, Kircher T, Lambert M, Mulert C, Pfennig A, Reif A, Rienhoff O, Schulze TG, Severus E, Stamm T, Bauer M (2016) Aims and structure of the German Research Consortium BipoLife for the study of bipolar disorder. Int J Bipolar Disord 4(1):26. https://doi.org/10.1186/s40345-016-0066-0

    Article  Google Scholar 

  • Rosa AR, Sanchez-Moreno J, Martinez-Aran A (2007) Validity and reliability of the Functioning Assessment Short Test (FAST) in bipolar disorder. Clin Pract Epidemiol Ment Health 3:5

    Article  Google Scholar 

  • Rush AJ, Giles DE, Schlesser MA, Fulton CL, Weissenburger J, Burns C (1986) The Inventory for Depressive Symptomatology (IDS): preliminary findings. Psychiatry Res 18(1):65–87

    Article  CAS  Google Scholar 

  • Schlotterbeck P, Leube D, Kircher T, Hiemke C, Gründer G (2007) Aripiprazole in human milk. Int J Neuropsychopharmacol 10(3):433. https://doi.org/10.1017/S1461145707007602

    Article  CAS  Google Scholar 

  • Schmidtke A, Fleckenstein P, Moises W, Beckmann H (1988) Untersuchungen zur Reliabilität und Validität einer deutschen Version der Montgomery-Asberg Depression Rating Scale. Arch Neurol Psychiatr 139:51–65

    CAS  Google Scholar 

  • Schneider F, Margraf J (2006) Diagnostisches Interview bei psychischen Störungen (DIPS für DSM-IV-TR), 3. Aufl. Springer, Berlin

    Google Scholar 

  • Shirdazi AA, Ghaemi SN (2006) Side effects of atypical antipsychotics: extrapyramidal symptoms and the metabolic syndrome. Harv Rev Psychiatry 14:152–164

    Article  Google Scholar 

  • Shugar G, Schertzer S, Toner BB, Digasbarro I (1992) Development, use, and factor-analysis of a self-report inventory for mania. Compr Psychiatry 33(5):325–331

    Article  CAS  Google Scholar 

  • Simpson GM, Angus JW (1970) A rating scale for extrapyramidal side effects. Acta Psychiatr Scand Suppl 212:11–19

    Article  CAS  Google Scholar 

  • Simpson SG, McMahon FJ, McInnis MG, Mackinnon DF, Edwin D, Folstein SE, DePaulo JR (2002) Diagnostic reliability of bipolar II disorder. Arch Gen Psychiatry 59(8):736–740

    Article  Google Scholar 

  • Smith DJ, Griffiths E, Kelly M, Hood K, Craddock N, Simpson SA (2011) Unrecognised bipolar disorder in primary care patients with depression. Br J Psychiatry 199(1):49–56

    Article  Google Scholar 

  • Spitzer RL, Kroenke K, Williams JB (1999) Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient health questionnaire. JAMA 282(18):1737–1744

    Article  CAS  Google Scholar 

  • Stieglitz RD, Smolka M, Bech P, Helmchen H (1998) Bech-Rafaelsen-Melancholie-Skala (BRMS). Handanweisung. Hogrefe, Göttingen

    Google Scholar 

  • Tomson T, Battino D, Perucca E (2016) Valproic acid after five decades of use in epilepsy. Time to reconsider the indications of a time-honoured drug. Lancet Neurol 15(2):210–218. https://doi.org/10.1016/S1474-4422(15)00314-2

    Article  CAS  Google Scholar 

  • Veiby G, Daltveit AK, Engelsen BA, Gilhus NE (2014) Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol 261(3):579–588. https://doi.org/10.1007/s00415-013-7239-x

    Article  CAS  Google Scholar 

  • Vieta E, Suppes T (2008): Bipolar II disorder: arguments for and against a distinct diagnostic entity. In: Bipolar Disord 10(1–2):163–178

    Google Scholar 

  • Vieta E, Phillips ML (2007) Deconstructing bipolar disorder: a critical review of its diagnostic validity and a proposal for DSM-V and ICD-11. Schizophr Bull 33(4):886–892. https://doi.org/10.1093/schbul/sbm057

    Article  Google Scholar 

  • Volkert J, Kopf J, Kazmaier J, Glaser F, Zierhut KC, Schiele MA, Kittel-Schneider S, Reif A (2015) Evidence for cognitive subgroups in bipolar disorder and the influence of subclinical depression and sleep disturbances. Eur Neuropsychopharmacol 25(2):192–202. https://doi.org/10.1016/j.euroneuro.2014.07.017

    Article  CAS  Google Scholar 

  • Watanabe N, Kasahara M, Sugibayashi R, Nakamura T, Nakajima K, Watanabe O, Murashima A (2011) Perinatal use of aripiprazole. A case report. J Clin Psychopharmacol 31(3):377–379. https://doi.org/10.1097/JCP.0b013e318218c400

    Article  Google Scholar 

  • Weiden PJ (2007) EPS profiles: the atypical antipsychotics are not all the same. J Psychiatr Pract 13(1):13–24

    Article  Google Scholar 

  • WHO (1990) World health organisation composite international diagnostic interview. World Health Organisation, Devision of Mental Health, Geneva

    Google Scholar 

  • WHO (1993) The schedules for clinical assessment in neuropsychiatry. World Health Organization – Division of Mental Health, Geneva

    Google Scholar 

  • WHO (2000) Internationale Klassifikation psychischer Störungen: ICD-10, Kapitel V (F); Diagnostische Kriterien für Forschung und Praxis, Bd 2, 2. Aufl. Huber, Bern

    Google Scholar 

  • Wittchen HU, Pfister H (1997) DIA-X-Interviews: Manual für Screening-Verfahren und Interview; Interviewheft Längsschnittuntersuchung (DIA-X-Lifetime); Ergänzungsheft (DIA-X-Lifetime); Interviewheft Querschnittuntersuchung DIA-X-12 Monate); Ergänzungsheft (DIA-X-12Monate); PC-Programm zur Durchführung des Interviews (Längs- und Querschnittuntersuchung); Auswertungsprogramm. Swets & Zeitlinger, Frankfurt

    Google Scholar 

  • Wittchen HU, Semler G (1990) Composite international diagnostic interview. Beltz, Weinheim

    Google Scholar 

  • Wittchen HU, Zaudig M, Fydrich T (1997) SKID. Strukturiertes Klinisches Interview für DSM-IV. Achse I und II. Hogrefe, Göttingen

    Google Scholar 

  • Yesavage JA, Brink TL, Rose TL (1982) Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 83(39):37–49

    Article  Google Scholar 

  • Young RC, Biggs JT, Ziegler VE, Meyer DA (1978) Rating-scale for mania – reliability, validity and sensitivity. Br J Psychiatry 133:429–435

    Article  CAS  Google Scholar 

  • Youngstrom EA, Birmaher B, Findling RL (2008) Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosis. Bipolar Disord 10(1):194–214

    Article  Google Scholar 

  • Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370

    Article  CAS  Google Scholar 

  • Zimmerman M, Coryell W, Corenthal C, Wilson S (1986) A self-report scale to diagnose major depressive disorder. Arch Gen Psychiatry 43(11):1076–1081

    Article  CAS  Google Scholar 

  • Meyer TD, Hautzinger M (2001) Allgemeine Depressions-Skala (ADS) – Normierung an Minderj„hrigen und Erweiterung zur Erfassung manischer Symptome (ADMS). Diagnostica 47:208–215

    Article  Google Scholar 

  • Angst J, Azorin Jean M, Bowden Charles L, Perugi G, Vieta E, Gamma Alex, Young Allan H (2011) Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. In: Archives of general psychiatry 68(8):791–798. https://doi.org/10.1001/archgenpsychiatry.2011.87

  • Bauer M, Severus E, Laux G (2017) Bipolare Affektive Störungen. In: Hans-Jürgen Möller, Gerd Laux und Hans-Peter Kapfhammer (Hg.): Psychiatrie, Psychosomatik, Psychotherapie. Springer: Berlin/Heidelberg

    Google Scholar 

  • Bauer M, Severus E, Laux G (2017b) Bipolare Affektive Störungen. In: Möller H-J, Laux G, Kapfhammer H-P (Hrsg) Psychiatrie, Psychosomatik, Psychotherapie. Springer: Berlin/Heidelberg

    Google Scholar 

  • Duffy et al. (2010) „Early stages in the development of bipolar disorder.“ J.Affect.Disord. 121(1–2):127–35

    Google Scholar 

  • Duffy et al. (2014b) „The developmental trajectory of bipolar disorder.“ Br.J.Psychiatry 204(2):122–28

    Google Scholar 

  • Birmaher et al. (2010) „Psychiatric disorders in preschool offspring of parents with bipolar disorder: the Pittsburgh Bipolar Offspring Study (BIOS).“ Am.J.Psychiatry 167(3):321–30

    Google Scholar 

  • Axelson et al. (2015) „Diagnostic Precursors to Bipolar Disorder in Offspring of Parents With Bipolar Disorder: A Longitudinal Study.“ Am.J.Psychiatry 172(7):638–46

    Google Scholar 

  • Hafeman et al. (2016) „Toward the Definition of a Bipolar Prodrome: Dimensional Predictors of Bipolar Spectrum Disorders in At-Risk Youths.“ Am.J.Psychiatry 173(7):695–704

    Google Scholar 

  • Levenson et al. (2015)“Differences in sleep disturbances among offspring of parents with and without bipolar disorder: association with conversion to bipolar disorder.“ Bipolar.Disord. 17(8):836–48

    Google Scholar 

  • Wals et al. (2001) „Prevalence of psychopathology in children of a bipolar parent.“ J.Am.Acad.Child Adolesc.Psychiatry 40(9):1094–102

    Google Scholar 

  • Mesman et al. (2013) „The Dutch bipolar offspring study: 12-year follow-up.“ Am.J.Psychiatry 170(5):542–49

    Google Scholar 

  • Kemner et al. (2015) „The role of life events and psychological factors in the onset of first and recurrent mood episodes in bipolar offspring: results from the Dutch Bipolar Offspring Study.“ Psychol.Med. 45(12):2571–81

    Google Scholar 

  • Mesman et al. (2015) „Monocyte activation, brain-derived neurotrophic factor (BDNF), and S100B in bipolar offspring: a follow-up study from adolescence into adulthood.“ Bipolar.Disord. 17(1):39–49

    Google Scholar 

  • Preisig M, Strippoli Marie-Pierre F, Castelao E, Merikangas Kathleen R, Gholam-Rezaee M, Marquet P (2016) The specificity of the familial aggregation of early-onset bipolar disorder: A controlled 10-year follow-up study of offspring of parents with mood disorders. In: Journal of affective disorders 190:26–33. https://doi.org/10.1016/j.jad.2015.10.005

  • Angst J, Gamma A, Endrass J, (2003) Risk factors for the bipolar and depression spectra. In: Acta psychiatrica Scandinavica 108(s418):15–19

    Google Scholar 

  • Egeland et al. (2012) „A 16-year prospective study of prodromal features prior to BPI onset in well Amish children.“ J.Affect.Disord. 142(1–3):186–92

    Google Scholar 

  • Tijssen et al. (2010) „Risk factors predicting onset and persistence of subthreshold expression of bipolar psychopathology among youth from the community.“ Acta Psychiatr.Scand. 122(3):255–66

    Google Scholar 

  • Ratheesh et al. (2015) „Prospective progression from high-prevalence disorders to bipolar disorder: Exploring characteristics of pre-illness stages.“ J.Affect.Disord. 183:45–48

    Google Scholar 

  • Lonnqvist et al. (2009) “Premorbid personality factors in schizophrenia and bipolar disorder: results from a large cohort study of male conscripts.“ J.Abnorm.Psychol. 118(2):418–23

    Google Scholar 

  • Kwapil et al. (2000) „A longitudinal study of high scorers on the hypomanic personality scale.“ J.Abnorm.Psychol. 109(2):222–26

    Google Scholar 

  • Blechert J & Thomas DM (2005) „Are measures of hypomanic personality, impulsive nonconformity and rigidity predictors of bipolar symptoms?“ British Journal of Clinical Psychology 44(1):15–27

    Google Scholar 

  • Alloy et al. (2012a) „High Behavioral Approach System (BAS) sensitivity, reward responsiveness, and goal-striving predict first onset of bipolar spectrum disorders: a prospective behavioral high-risk design.“ J.Abnorm.Psychol. 121(2):339–51

    Google Scholar 

  • Stange Jonathan P, Sylvia, Louisa G, Magalhaes Pedro Vieira da S, Frank E, Otto Michael W, Miklowitz David J (2013) Extreme attributions predict transition from depression to mania or hypomania in bipolar disorder. In: Journal of psychiatric research 47(10):1329–1336. https://doi.org/10.1016/j.jpsychires.2013.05.016

  • Molz et al. (2013) „Aggression and Impulsivity as Predictors of Stress Generation in Bipolar Spectrum Disorders.“ J.Affect.Disord. 146(2):272–80 Papachristou, E., et al. „Child Behavior Checklist-Mania Scale (CBCL-MS): development and evaluation of a population-based screening scale for bipolar disorder.“ PLoS.One. 8(8). e69459

    Google Scholar 

  • Bombin et al.(2013) „Neuropsychological evidence for abnormal neurodevelopment associated with early-onset psychoses.“ Psychol.Med. 43(4):757–68

    Google Scholar 

  • Bootsman et al. (2016) „A study of genetic and environmental contributions to structural brain changes over time in twins concordant and discordant for bipolar disorder.“ J.Psychiatr.Res. 79:116–24

    Google Scholar 

  • Papmeyer M et al. (2016) „Prospective longitudinal study of subcortical brain volumes in individuals at high familial risk of mood disorders with or without subsequent onset of depression.“ Psychiatry Res. 248:119–25

    Google Scholar 

  • Farrow et al. (2005) „Diagnosis-related regional gray matter loss over two years in first episode schizophrenia and bipolar disorder.“ Biol.Psychiatry 58.9 (2005): 713–23

    Google Scholar 

  • Bitter et al. (2011) „Progression of amygdala volumetric abnormalities in adolescents after their first manic episode.“ J.Am.Acad.Child Adolesc.Psychiatry 50(10):1017–26

    Google Scholar 

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    1. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

      Michael Bauer

    2. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

      Andrea Pfennig

    3. Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

      Martin Schäfer

    4. Ludwig-Maximilians-Universität, Klinik für Psychiatrie + Psychother, München, Bayern, Germany

      Peter Falkai

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    DGBS., DGPPN. (2020). Klassifikation und Diagnostik inklusive Früherkennung. In: Bauer, M., Pfennig, A., Schäfer, M., Falkai, P. (eds) S3-Leitlinie zur Diagnostik und Therapie Bipolarer Störungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-61153-1_4

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