Zusammenfassung
Die Akanthamöben-Keratitis ist eine seltene aber oft schwer verlaufende Infektion der Cornea, die - zumindest in den westlichen Industrienationen - in erster Linie bei Kontaktlinsenträgern auftritt. Der Hauptrisikofaktor ist unzureichende Kontaktlinsen-Hygiene.
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Notes
- 1.
Posttraumatischer Kontakt zu verunreinigtem Wasser.
Literatur
Arnalich-Montiel F, Reyes-Batlle M, López-Vélez R, Lorenzo-Morales J (2018) Treatment of intraocular spread of acanthamoeba after tectonic corneal graft in acanthamoeba keratitis. Eye (Lond) 32(7):1286–1287. https://doi.org/10.1038/s41433-018-0041-3
Baker MS, Maltry AC, Syed NA, Allen RC (2018) Orbital implant exposure after Acanthamoeba panophthalmitis. Am J Ophthalmol Case Rep 10:48–50. https://doi.org/10.1016/j.ajoc.2018.01.043
Carnt N, Hoffman JJMBBS, Verma S, Hau S, Radford CF, Minassian DC, Dart JKG (2018) Acanthamoeba keratitis: confirmation of the UK outbreak and a prospective case-control study identifying contributing risk factors. Br J Ophthalmol 102(12):1621–1628. https://doi.org/10.1136/bjophthalmol-2018-312544
De Craene S, Knoeri J, Georgeon C, Kestelyn P, Borderie VM (2018) Assessment of confocal microscopy for the diagnosis of polymerase chain reaction-positive acanthamoeba keratitis: a case-control study. Ophthalmology 125(2):161–168. https://doi.org/10.1016/j.ophtha.2017.08.037
Dewan N, Ming W, Holland SP, Yeung SN, Iovieno A (2019) Oral miltefosine as adjunctive treatment for recalcitrant acanthamoeba keratitis. Cornea 38(7):914–917. https://doi.org/10.1097/ICO.0000000000001968
Fraser MN, Wong Q, Shah L, Holland SP, Morshed M, Isaac-Renton J, Chong M, Kibsey P, Patrick DM (2012) Characteristics of an Acanthamoeba keratitis outbreak in British Columbia between 2003 and 2007. Ophthalmology 119(6):1120–1125. https://doi.org/10.1016/j.ophtha.2011.12.041
Hiti K, Walochnik J, Haller-Schober EM, Faschinger C, Aspöck H (2006) A new multipurpose contact lens disinfection system in comparison with eight other solutions – effectiveness against acanthamoeba. Cornea 25(4):423–427
Köhsler M, Mrva M, Walochnik J (2016) Acanthamoeba. In: Walochnik J, Duchêne M (Hrsg) Molecular parasitology – protozoan parasites and their molecules. Springer Publishing, Vienna, S 285–324
Lorenzo-Morales J, Khan NA, Walochnik J (2015) An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment. Parasite 22(10):1–20
Maycock NJ, Jayaswal R (2016) Update on acanthamoeba keratitis: diagnosis, treatment, and outcomes. Cornea 35(5):713–720. https://doi.org/10.1097/ICO.0000000000000804. Review
McKelvie J, Alshiakhi M, Ziaei M, Patel DV, McGhee CN (2018) The rising tide of Acanthamoeba keratitis in Auckland, New Zealand: a 7-year review of presentation, diagnosis and outcomes (2009-2016). Clin Exp Ophthalmol 46(6):600–607. https://doi.org/10.1111/ceo.13166
Nateghi Pettersson M, Lagali N, Mortensen J, Jofré V, Fagerholm P (2019) High fluence PACK-CXL as adjuvant treatment for advanced Acanthamoeba keratitis. Am J Ophthalmol Case Rep 15:100499. https://doi.org/10.1016/j.ajoc.2019.100499
Neelam S, Niederkorn JY (2017) Pathobiology and immunobiology of acanthamoeba keratitis: insights from animal models. Yale J Biol Med 90(2):261–268
Papa V, Rama P, Radford C, Minassian DC, Dart JKG (2019. pii: bjophthalmol-2019-314485) Acanthamoeba keratitis therapy: time to cure and visual outcome analysis for different antiamoebic therapies in 227 cases. Br J Ophthalmol. https://doi.org/10.1136/bjophthalmol-2019-314485
Polat ZA, Obwaller A, Vural A, Walochnik J (2012) Efficacy of miltefosine for topical treatment of Acanthamoeba keratitis in Syrian hamsters. Parasitol Res 110(2):515–520
Roozbahani M, Hammersmith KM, Rapuano CJ, Nagra PK, Zhang Q (2019) Therapeutic penetrating keratoplasty for acanthamoeba keratitis: a review of cases, complications and predictive factors. Int Ophthalmol. https://doi.org/10.1007/s10792-019-01137-1
Szentmáry N, Daas L, Shi L, Laurik KL, Lepper S, Milioti G, Seitz B (2018) Acanthamoeba keratitis − Clinical signs, differential diagnosis and treatment. J Curr Ophthalmol 31(1):16–23. https://doi.org/10.1016/j.joco.2018.09.008
Tavassoli S, Buckle M, Tole D, Chiodini P, Darcy K (2018) The use of miltefosine in the management of refractory Acanthamoeba keratitis. Cont Lens Anterior Eye (17):30403–30404. pii: S1367-0484. https://doi.org/10.1016/j.clae.2018.03.007
Teuchner B, Wibmer ID, Schaumann P, Seifarth C, Walochnik J, Nagl M (2019) N-chlorotaurine inactivates acanthamoeba and candida albicans in the porcine ex vivo corneal infection model. Cornea 38(8):1011–1016
Walochnik J, Aspöck H (2005) Die Diagnostik von Infektionen mit freilebenden Amöben (FLA). J Lab Med 29(6):446–456
Yoder JS, Verani J, Heidman N, Hoppe-Bauer J, Alfonso EC, Miller D, Jones DB, Bruckner D, Langston R, Jeng BH, Joslin CE, Tu E, Colby K, Vetter E, Ritterband D, Mathers W, Kowalski RP, Acharya NR, Limaye AP, Leiter C, Roy S, Lorick S, Roberts J, Beach MJ (2012) Acanthamoeba keratitis: the persistence of cases following a multistate outbreak. Ophthalmic Epidemiol 19(4):221–225. https://doi.org/10.3109/09286586.2012.681336
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Walochnik, J., Aspöck, H. (2021). Akanthamöben-Keratitis (AK) (engl. Acanthamoeba keratitis). In: Pleyer, U. (eds) Entzündliche Augenerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60399-4_10
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