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Nanotechnology-Based Stem Cell Tissue Engineering with a Focus on Regeneration of Cardiovascular Systems

  • Srikanth Sivaraman
  • Arvind Sinha
  • Ki-Taek Lim
  • Jin-Woo KimEmail author
  • Raj RaoEmail author
  • Hanna JensenEmail author
Chapter

Abstract

This chapter outlines the main stem cell lines and nanomaterials utilized in tissue engineering for regenerative medicine, with a distinct focus on the cardiovascular system, which is our research area of interest.

Abbreviations

AFPC

Amniotic fluid progenitor cells

AgNP

Silver nanoparticle

AuNP

Gold particle

bFGF

Basic fibroblast growth factor

BM-MSC

Bone marrow-derived mesenchymal stem cells

CAD

Computer-aided software

CAFC

Cobblestone area formation assay

CFU

Colony formation unit assay

CM

Cardiomyocyte

CNC

Cellulose nanocrystals

CNT

Carbon nanotube

CRU

Competitive repopulating unit assay

CVD

Chemical vapor deposition

DNA

Deoxyribonucleic acid

EB

Embryoid body

EC

Endothelial cell

ECM

Extracellular matrix

ESC

Embryonic stem cells

FACS

Fluorescence-activated cell sorting

FDM

Fused deposition modeling

FGF

Fibroblast growth factor

GelMA

Carbon nanotube-gelatin methacrylate

GM

Gelatin microspheres

GO

Graphene oxide

HA

Hyaluronic acid

HAp/CS-Gel

Hydroxyapatite/chitosan–gelatin

hASCs

Human adipose mesenchymal stem cells

hESC

Human embryonic stem cells

HIPE

High internal phase emulsion

hNSCs

Human neural stem cells

HSCs

Hematopoietic stem cells

IGF

Insulin growth factor

iPSC

Induced pluripotent stem cells

KOSR

Knockout serum replacement

LIF

Leukemia inhibitory factor

LSPR

Localized surface plasma resonance

LT-IC

Long-term culture initiation assay

MI

Myocardial infarction

miRNA

Micro-RNA

MRI

Magnetic resonance imaging

MSC

Mesenchymal stromal cells

MWNT

Multi-walled carbon nanotube

NFC-X

Nanofibrillated cellulose

NF-kB

Nuclear factor kappa-light-chain-enhancer of activated B cells

NPs

Nanoparticles

PBAE

Biodegradable poly (β-amino-ester)

PCL

Polycaprolactone

PEG-DA

Polyethylene (glycol) diacrylate

PEI

Polyethyleneimine

PGLA

Polylactic-co-glycolic acid

PLA

Polylactic acid

PS

Protamine sulfate

QD

Quantum dot

RBMSCs

Rat bone marrow stromal cells

RGO

Reduced graphene oxide

RNA

Ribonucleic acid

SCNT

Somatic cell nuclear transfer

SG

Single-layer graphene

SL

Stereolithography

SPIO

Superparamagnetic iron oxide nanoparticle

SWNT

Single-walled carbon nanotube

TCP

Tricalcium phosphate

TGF

Transforming growth factor

TiO2NP

Titanium dioxide-based nanoparticle

UDSCs

Urine-derived stem cells

VEGF

Vascular endothelial growth factor

ZnONP

Zinc-oxide-based nanoparticle

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Biomedical EngineeringUniversity of ArkansasFayettevilleUSA
  2. 2.Department of Biological and Agricultural EngineeringUniversity of ArkansasFayettevilleUSA
  3. 3.Institute for Nanoscience and EngineeringUniversity of ArkansasFayettevilleUSA
  4. 4.Department of Biosystems EngineeringKangwon National UniversityChuncheonRepublic of Korea

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