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Chemische Ablationsverfahren

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Varikose

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Zusammenfassung

Die Indikationsstellung zur Verödungstherapie der primären Varikose hat wie viele andere Bereiche in der Phlebologie einen Wandel durchgemacht. Während einer der Pioniere der modernen Verödungstherapie, Karl Sigg, noch davon ausging, dass grundsätzlich alle Typen und Ausdehnungen von Krampfadern – einschließlich der Stammveneninsuffizienz – der Verödungstherapie zugänglich seien, wurde in den letzten Jahrzehnten des vergangenen Jahrhunderts die Sklerosierungstherapie mehr als adjuvante Therapie zusätzlich zur operativen Sanierung der Varikose gesehen. Die Wiederentdeckung und Wiederbelebung der Schaumverödung hat dann in den letzten Jahren erneut zu einer Ausdehnung der Indikation zur Verödungstherapie auch auf die Stammvarikose geführt. Die endovenösen Techniken haben sich in den vergangenen 10 Jahren als effektive Konkurrenz zum offen chirurgischen Verfahren zur Behandlung der Stammvarikosis in allen klinischen Stadien entwickelt. Dies betrifft die Laser- und Hochfrequenztherapie, die auf der Applikation von thermischer Energie basieren, wie auch das nichtthermale Ablationsverfahren, die mechanisch-chemische Ablation (MOCA) und das endovenöse, Katheter-gestützte Klebeverfahren mit Cyanoacrylat in seinen beiden Varianten mit flüssigem und gelförmigen Cyanacrylat.

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Literatur

  • http://www.general-anaesthesia.com/people/charles-pravaz.html. (2009)

  • Almeida JI, Min RJ, Raabe R, McLean DJ, Madsen M (2011) Cyanoacrylate adhesive for the closure of truncal veins: 60-day swine model results. Vasc Endovascular Surg 45:631–635

    Article  PubMed  Google Scholar 

  • American College of Phlebology Practice Guidelines: Superficial Venous Disease rev102314, Phlebology.org. Zugegriffen: März 2017

    Google Scholar 

  • Baccaglini U, Stemmer R, Partsch U (1997b) Internationale Fragebogenaktion zur Praxis der Verödungsbehandlung. Phlebologie 26:129–142

    Google Scholar 

  • Baccaglini U, Spreafico G, Castoro C, Sorrentino P (1997c) Consensus conference on sclerotherapy or varicose veins of the lower limbs. Phlebology 12:2–16

    Google Scholar 

  • Baccaglini U, Spreafico G, Castoro C, Sorrentino P (1997a) Consensus conference on sclerotherapy or varicose veins of the lower limbs. Phlebology 12:2–16

    Google Scholar 

  • Barrett JM, Allen B, Ockelford A, Goldman MP (2004) Microfoam ultrasound-guided sclerotherapy of varicose veins in 100 legs. Dermatol Surg 20(1):6–12

    Google Scholar 

  • Belcaro G et al (2002) Comparison among treatment schemes for varicose veins: surgery, sclerotherapy, foam sclerotherapy and combined options – a 10-year, prospective, randomised, follow-up study the VEDICO trial and EST (European Sclerotherapy Trial). In: Belcaro G, Geroulakos G, Cesarone MR et al (Hrsg) Sclerotherapy in venous disease. Edizioni Minerva Medica, Torino, S 96–104

    Google Scholar 

  • Bergan JJ, Weiss RA, Goldman MP (2000) Extensive tissue necrosis following high concentration sclerotherapy for varicose veins. Dermatol Surg 26:535–542

    Article  CAS  PubMed  Google Scholar 

  • Biegeleisen HI (1937) Fatty acid Solutions for the injection treatment of varicose veins: evaluation of four new solutions. Ann Surg 105(4):610–615

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bischoff JK (1993) Phlebologie: von der Empirie zur Wissenschaft. Fischer, Jena

    Google Scholar 

  • Bishawi M, Bernstein R, Boter M et al (2013) Mechanochemical ablation in patients with chronic venous disease: a prospective multicenter report. Phlebology 29:397–400

    Article  PubMed  Google Scholar 

  • Boersma D, van Eekeren RR, Werson DA et al (2013) Mechanochemical endovenous ablation of small saphenous vein insufficiency using the ClariVein® device: one-year results of a prospective series. Eur J Vasc Endovasc Surg 45:299–303

    Article  CAS  PubMed  Google Scholar 

  • Boersma D, Kornmann VN, van Eeckeren RR, Tromp E, Ünlü C, Reijnen RR, de Vries JP (2016) Treatment modalities for small saphenous vein insufficiency: systematic review and meta-analysis. J Endovasc 23(1):199–211

    Article  Google Scholar 

  • Bootun R, Lane TRA, Dharmarajah B, Lim CS, Najem M, Renton S, Sritharan K, Davies AH (2014) Intra-procedural pain score in a randomised controlled trial comparing mechanochemical ablation to radiofrequency ablation: The Multicentre Venefit™ versus ClariVein® for varicose veins trial. Phelbology 31(1):61–65

    Google Scholar 

  • Breu FX, Guggenbichler S (2004) European consensus meeting on foam sclerotherapy. April, 4–6, 2003, Tegernsee Germany. Dermatol Surg 5:709–717

    Article  Google Scholar 

  • Breu FX, Guggenbichler WJC (2008) 2nd European consensus meeting on foam sclerotherapy, 28–30 April 2006, Tegernsee Germany. Vasa 1(71):1–32

    Google Scholar 

  • Breu FX, Partsch B (2006) Reversible neurologische Komplikationen bei der Schaum-Sklerotherapie. Phlebologie 3:115–116

    Article  Google Scholar 

  • Breu FX, Guggenbichler S (2004) European consensus meeting on foam sclerotherapy. April, 4–6, 2003 Tegernsee, Germany. Dermatol Surg 30(5):709–717

    Google Scholar 

  • Breu FX, Guggenbichler, Wollmann JC. (2008) 2nd European consensus meeting on foam sclerotherapy, 28–30 April 2006, Tegernsee, Germany. Vasa 37(1) Supplement 71:1–32

    Google Scholar 

  • Buess H (1946) Die historischen Grundlagen der intravenösen Injektion ein Beitrag zur Medizingeschichte des 17. Jahrhunderts. H. R. Sauerländer (Aarau in der Schweiz)

    Google Scholar 

  • Bullens-Goessens YIJM, Mentink LF, Nelemans PJ, Van Geest AJ, Veraart JCJM (2004) Ultrasound-guided sclerotherapy of the insufficient short saphenous vein. Phlebologie 33(3):89–91

    Article  Google Scholar 

  • Cavezzi A, Frullini A, Ricci S, Tessari L (2002) Treatment of varicose veins by foam sclerotherapy: two clinical series. Phlebology 17:13–18

    Article  Google Scholar 

  • Ceulen RP, Jagtman EA, Sommer A, Teule GJ, Schurink GW (2010) Kemmerink GJ Blocking the sapheno-femoral junction during ultrasound guided foam sclerotherapy assessmant of a presumed safety-measure procedure. Eur J Vasc Endovasc Surg 40(6):772–776

    Article  CAS  PubMed  Google Scholar 

  • Ceulen RPM, Bullens-Goessens YIJM, Pi-Van De Venne SJA (2007) Outcomes and side effects of duplex-guided sclerotherapy in the treatment of great saphenous veins with 1 % versus 3 % Polidocanol foam: Results of a randomized controlled trial with 1-year follow-up. Dermatol Surg 33(3):276–281

    Google Scholar 

  • Chan YC, Law Y, Cheung GC, Ting AC, Cheng SW (2016) Cyanoacrylate glue used to treat great saphenous reflux: Measures of outcome. Phlebology 2: 99–106

    Google Scholar 

  • Conrad P, Malouf GM, Stacey MC (1995) The Australian Polidocanol (Aethoxysklerol) study. Results at 2 years. Dermatol Surg 21:334–336

    Google Scholar 

  • Deijen CL, Schreve MA, Bosma J, de Nie AJ, Leijdekkers VJ, van den Akker PJ, Vahl A (2016) Clarivein mechanochemical ablation of the great and small saphenous vein: Early treatment outcomes of two hospitals. Phlebology 31(3):192–197

    Google Scholar 

  • Drake LA, Dinehart SM, Goltz RW, Graham GF, Hordinsky MK, Lewis CW, Pariser DM, Skouge JW, Webster SB, Whitaker DC, Butler B, Lowery BJ (1996) Guidelines of care for sclerotherapy treatment of varicose and teleangiectatic leg veins. J Am Acad Dermatol 34:523–528

    Article  Google Scholar 

  • Duffy DM (1999) Cutaneous necrosis following sclerotherapy. J Anesthetic Dermatol Cosmetic Surg 1(2):157–168

    Google Scholar 

  • van Eekeren RR, Boersma D, Elias S, Holewijn S, Werson DA, deVries JP, Reijnen MM (2011) Endovenous mechanochemical ablation of great saphenous vein incompetence using the ClariVein device:a safety study. J Endovasc Ther 18:328–334

    Article  PubMed  Google Scholar 

  • Einarsson E, Eklöf B, Neglén P (1993) Sclerotherapy or surgery as treatment for varicose veins: a prospective randomized study. Phlebology 8:22–26

    Article  Google Scholar 

  • Elias S, Raines JK (2012) Mechanochemical tumescentless endovenous ablation: final results of the initial clinical trial. Phlebology 27:67–72

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fachinformation Äthoxysklerol, Chemische Fabrik Keussler&Co. GmbH, Wiesbaden

    Google Scholar 

  • Fegan WG (1963) Continuous compression technique of injecting varikose veins. Lancet 2:109

    Article  CAS  PubMed  Google Scholar 

  • Feied CF (1993a) Deep vein thrombosis: the risks of sclerotherapy in hypercoagulable states. Sem Dermatol 2:135–149

    Google Scholar 

  • Feied CF (1993b) Deep vein thrombosis: the risks of sclerotherapy in hypercoagulable states. Sem Dermatol 12(2):135–149

    CAS  Google Scholar 

  • Feied CF, Jackson JJ, Bren TS, Bond OB, Fernando CE, Young VC, Hashemiyoon RB (1994) Allergic reactions to polidocanol for vein sclerosis. J Dermatol Surg Oncol 20:466–468

    Article  CAS  PubMed  Google Scholar 

  • Fisher DA (2000) Regarding extensive tissue necrosis following high concentration sclerotherapy for varicose veins. Dermatol Surg 26(11):1081

    Article  Google Scholar 

  • Frullini A, Cavezzi A (1999) Ultrasound guided sclerotherapy in the treatment of long saphenaous vein insufficiency. Vasomed 11(1):8

    Google Scholar 

  • Gedeon (2006) Science and technology in medicine: an illustrated account based on ninety-nine landmark publications from five centuries. Springer, Berlin S 71

    Google Scholar 

  • Georgiev M (1993) Postsclerotherapy hyperpigmentations. J Dermatol Surg Oncol 19:649–652

    Article  CAS  PubMed  Google Scholar 

  • Geukens J, Rabe E, Bieber T (1999) Embolia cutis medicamentosa of the foot after sclerotherapy. Eur J Dermatol 9:132–133

    CAS  PubMed  Google Scholar 

  • Gibson K, Ferris B (2017) Cyanoacrylate closure of incompetent great, small and accessory saphenous veins without the use of post-procedure compression: Initial outcomes of a post-market evaluation of the VenaSeal System (the WAVES Study). Vascular 25(2):149–156

    Article  PubMed  Google Scholar 

  • Gloviczki P (Hrsg) (2017) Handbook of venous and lymphatic disorders, 4. Aufl. CRC Press, New York

    Google Scholar 

  • Goldman PM, Beaudoing D, Marley W, Lopez L, Butie A (1990) Compression in the treatment of leg teleangiectasia: a preliminary report. J Dermatol Surg Oncol 16:322–325

    Article  CAS  PubMed  Google Scholar 

  • Goldman MP, Bennet R (1987) Treatment of telangiectasia: a review. J Am Acad Dermatol 17(2 Pt 1):167–182

    Article  CAS  PubMed  Google Scholar 

  • Goldman MP, Sadick NS, Weiss RA (1995) Cutaneous necrosis, telangiectatic matting and hyperpigmentation following sclerotherapy. Dermatol Surg 21:19–29

    Article  CAS  PubMed  Google Scholar 

  • Goldmann PM, Bergan JJ, Guex JJ (2007) Sclerotherapy – Treatment of varicose veins and telangiectatic leg veins, 4. Aufl. Mosby Elsevier, Philadelphia

    Google Scholar 

  • Guex JJ (2000) Ultrasound Guided Sclerotherapy (USGS) for perforating veins. Hawaii Med J 59(6):261–262

    CAS  PubMed  Google Scholar 

  • Guex JJ, Allaert F-A, Gillet JL (2005) Immediate and midterm complications of sclerotherapy: report of a prospective multicenter registry of 12,173 sclerotherapy sessions. Dermatol Surg 31(2):123–128

    Article  CAS  PubMed  Google Scholar 

  • Guex JJ, Schliephake DE, Otto J, Mako S, Allaert SA (2010) the French polidocanol study on long term side effects, a survey covering 3357 patient years. Dermatol Surg 36(2):993–1003

    Article  CAS  PubMed  Google Scholar 

  • Hamel-Desnos C, Desnos P, Wollmann JC et al (2003b) Evaluation of the efficacy of Polidocanol in the form of foam compared with liquid form in sclerotherapy of the long saphenous vein: Initial results. Dermatol Surg 29(12):1170–1175

    PubMed  Google Scholar 

  • Hamel-Desnos C, Ouvry P, Desnos P, Escalard JM, Allaert FA (2003a) Sclérothérapie et thrombophilie: Démarche pour un consensus dans la sclérothérapie chez les thrombophiles. Phlebologie 56:165–169

    Google Scholar 

  • Hamel-Desnos CM, Gillet JL, Desnos PR, Allaert FA (2009) sclerotherapy of varicous veinsin patients with documented thrombophilia: a prospective controlled randomized study of 105 cases. Phlebology 24(4):176–182

    Google Scholar 

  • Hauer G (1984) German patent DE 34 17 182 C2. Zwillings-Spritzen-Set, 9 May 1984.

    Google Scholar 

  • Hertzman PA, Owens R (2007) Rapid healing of chronic venous ulcers following ultrasound-guided foam sclerotherapy. Phlebology 22(1):34–39

    Google Scholar 

  • Hohlbaum G (1990) Über iatrogene Schäden bei der Varizensklerosierung. In: Staubesand J, Schöpf E (Hrsg) Neuere Aspekte der Sklerosierungstherapie. Springer, Berlin, 70–81

    Google Scholar 

  • Holzegel K (1970) Über Varizenverödungsmittel. Zentralbl Phlebol 9:43–52

    Google Scholar 

  • Hübner K (Hrsg) (2005) Praktische Sklerotherapie. Viavital, Essen

    Google Scholar 

  • Hübner K (2008) Praktische Sklerotherapie. Viavital, Essen

    Google Scholar 

  • Imhoff E, Stemmer R (1969) Classification et mécanisme d’action des sclérosants. Phlebologie 22:143–148

    Google Scholar 

  • Kahle B, Leng K (2004) Efficacy of sclerotherapy in varicose veins – a prospective, blinded placebocontrolled study. Dermatol Surg 30:723–728

    PubMed  Google Scholar 

  • Kahle B (2006) Effizienz der Sklerosierungstherapie von Besenreisern. Eine prospektive, randomisierte, doppelblinde, placebokontrollierte Studie. Vasomed 18(4):148

    Google Scholar 

  • Kendler M, Averbeck M, Simon JC, Ziemer M (2013) Histology of saphenous veins after treatment with the ClariVein® device – an ex-vivo experiment. JDDG 11(4):348–352

    Google Scholar 

  • Kern P, Ramelet AA, Wütschert R et al (2004) Single-blind, randomized study comparing chromated glycerin, polidocanol solution and Polidocanol foam for treatment of telangiectatic leg veins. Dermatol Surg 3:367–372

    Google Scholar 

  • Kern P, Ramelet AA, Wütschert R, Hayoz D. (2007) Compression after sclerotherapy for telangiectasias and reticular leg veins. A randomized controlled study. J Vas Surg 45(6):1212–1216

    Google Scholar 

  • Kern P, Ramelet AA, Wütschert R, Hayoz D (2007) Compression after sclerotherapy for telangiectasias and reticular leg veins. A randomized controlled study. J Vas Surg 45(6):1212–1216

    Google Scholar 

  • Kersting E, Hornschuh B, Bröcker E-B (1998) Embolia cutis medicamentosa nach Varizensklerosierung mit Polidocanol. Phlebologie 27:55–57

    Article  Google Scholar 

  • Knight RM,Vin F, Zygmunt JA (1989) Ultrasonic guidance of injection into the superficial venous system. In: Davy A, Stemmer R (Hrsg) Phlébologie ’89. John Libbey Eurotext Ltd, Montrouge, S 339–341

    Google Scholar 

  • Kolluri R, Gibson K, Cher D et al (2016) Roll-in phase analysis of clinical study of cyanoacrylate closure for incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord 4(4):407–415

    Article  PubMed  Google Scholar 

  • Kreussler: Fachinformationen Aethoxysklerol 0,25 %/0,5 %/1 %/2 % Stand 06/2005, Aethoxysklerol 3 %/4 %, Stand 09/2005, Chemische Fabrik Kreussler & Co GmbH

    Google Scholar 

  • Kreussler (2005) Fachinformationen Aethoxysklerol 0,25 %/0,5 %/1 %/2 % Stand 06/2005, Aethoxysklerol 3 %/4 %, Stand 09/2005, Chemische Fabrik Kreussler & Co GmbH

    Google Scholar 

  • Künzelberger B, Pieck C, Altmeyer P, Stücker M (2006) Migraine ophthalmique with reversible scotomas after sclerotherapy with liquid 1 % polidocanol. Derm Surg 32:1410

    Google Scholar 

  • Lam YL, Toonder IM, Wittens CH (2016) Clarivein® mechano-chemical ablation an interim analysis of a randomized controlled trial dose-finding study. Phlebology 31:170–176

    Article  CAS  PubMed  Google Scholar 

  • Lauer HH (1972) Venen und Venenerkrankungen in historischer Sicht. Die Kapsel 29:1267–1279

    Google Scholar 

  • Lawson J, Gauw S, van Vlijmen C, Pronk P, Gaastra M, Mooij M, Wittens CH (2013) Sapheon: the solution? Phlebology 28(1):2–9.

    Google Scholar 

  • Lee C, Li JM, Whiteley MS (2014) Mechanochemical Ablation (MOCA) increases endothelial damage and penetration of damage into the media layer of the vein wall compared to sclerotherapy alone – a study using histology and immunohistochemistry. Presented at: American College of Phlebology, Phoenix, November.

    Google Scholar 

  • Malouf GM (2000) (2000) Ambulatory venous surgery versus sclerotherapy. Hawaii Med J 59:248–249

    CAS  PubMed  Google Scholar 

  • Massay RA (1999) Regarding the use of compression stockings after sclerotherapy. Dermatol Surg 1999(25):517

    Article  Google Scholar 

  • Mc Donagh B (1999) (1999) Comments on the use of post-sclerotherapy compression. Dermatol Surg 25(6):519–521

    Article  CAS  Google Scholar 

  • McAusland S (1939) The modern treatment of varicose veins. Med Press Circular 201:404–410

    Google Scholar 

  • McCoy S, Evans A, Spurrier N (1999) sclerotherapy for leg telangiectasia – a blinded comparative trial of polidocanol and hypertonic saline. Dermatol Surg 25:381–386

    Article  CAS  PubMed  Google Scholar 

  • Min RJ, Almeida JI, McLean DJ, Madsen M, Raabe R (2012) Novel vein closure procedure using a proprietary cyanoacrylate adhesive: 30-day swine model results. Phlebology 27: 398–403

    Google Scholar 

  • Monfreux A (1997) Traitement Sclérosant des Troncs Saphèniens et leurs Collatèrales de Gros Calibre par la Méthode Mus. Phlebologie 50(3):351–353

    Google Scholar 

  • Moore HM, Lane TR, Franklin IJ et al (2014) Retrograde mechanochemical ablation of the small saphenous vein for the treatment of a venous ulcer. Vascular 22:375–357

    Article  PubMed  Google Scholar 

  • Morrison N, Gibson K, Vasquez M et al (2017) VeClose trial: 12-month outcomes of cyanoacrylate closure versus radiofrequency ablation for incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord 5(3):321–330

    Google Scholar 

  • Mueller RL, Raines JK (2013) ClariVein mechanochemical ablation: background and details. Vasc Endovasc Surg 47(3):195–206

    Article  Google Scholar 

  • Myers KA, Jolley D, Clough A et al (2007) Outcome of ultrasound-guided sclerotherapy for varicose veins: medium-term results assessed by ultrasound surveillance. Eur J Vasc Endovasc Surg 33(1):116–121

    Article  CAS  PubMed  Google Scholar 

  • Myers K (2018) A history of injection treatments – II sclerotherapy. Phlebology 0(0):1–8

    Google Scholar 

  • Norris MJ, Carlin MC, Ratz JL (1989) Treatment of essential telangiectasia: effects of increasing concentrations of polidocanol. J Am Acad of Dermatol 20(4):643–649

    Article  CAS  Google Scholar 

  • Oesch A, Stirnemann P (1984) Mahler F (1984) The acute ischemic syndrome of the foot after sclerotherapy of varicose veins. Schweiz Med Wochenschr 114:1155–1158

    CAS  PubMed  Google Scholar 

  • Orbach EJ (1944) Sclerotherapy of varicose veins – utilization of an intravenous air block. Am J Surg LXV I(3):362–366

    Article  Google Scholar 

  • Orbach EJ (1950) A new approach to the sclerotherapy of varicose veins. Angiology 1:302

    Article  CAS  PubMed  Google Scholar 

  • Orbach EJ, Petretti AK (1950) The thrombogenic property of foam of a synthetic anionic detergent. Angiology 1:237–243

    Article  CAS  PubMed  Google Scholar 

  • Özen YD, Çekmecelioğlu S, Sarikaya S, Rabuş MR, Aydin E, Dedemoğlu M, Kirali K (2015) Mechano-chemical endovenous ablation of great saphenous vein insufficiency:two-year results. Damar Cer Derg [Turkish Journal of Vascular Sugery] 23:176–179

    Google Scholar 

  • Pannier F, Noppeney T (2019) Leitlinie Therapie der Varikose. AWMF-Leitlinien-Register-Nr. XXXXX

    Google Scholar 

  • Park I (2017) Initial outcomes of cyanoacrylate closure, venaseal system, for the treatment of the incompetent great and small saphenous veins. Vasc Endovascular Surg 51(8):545–549

    Article  PubMed  Google Scholar 

  • Partsch B (2004) Die Schaumverödung – eine Renaissance der Sklerotherapie. Phlebologie 33:30–36

    Article  Google Scholar 

  • Pascarella L, Bergan JJ, Mekenas LV (2006) Severe chronic venous insufficiency treatet by foam sclerosant. Ann Vasc Surg 20:83–91

    Article  PubMed  Google Scholar 

  • Van der Plas JPL, Lambers JC, van Wersch JW, Koehler PJ (1994) Reversible ischaemic neurological deficit after sclerotherapy of varicose veins. Lancet 343:428

    Article  PubMed  Google Scholar 

  • Pravaz M (1853) Sur un nouveau moyen d’opérer du sang dans les artères, applicable à la guérison des anevrismes. Bulletin Général de Thérapeutique 14(4):1853

    Google Scholar 

  • Proebstle TM, Alm J, Dimitri S, Rasmussen L, Whiteley M, Lawson J, Cher D, Davies A (2017) The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord 3: 2–7

    Google Scholar 

  • Rabe E, Breu FX et al (2014) European guidelines for sclerotherapy in chronic venous disorders. Phlebology 29:338–354

    Article  CAS  PubMed  Google Scholar 

  • Rabe E, Otto J, Schliephake D, Pannier F (2008) Efficacy and safety of great saphenous vein sclerotherapy using standardised polidocanol foam (ESAF): a randomised controlled multicentre clinical trial. Eur J Endovasc Vasc Surg 35(2):238–245

    Article  CAS  Google Scholar 

  • Rabe E, Otto J, Schliephake D, Pannier F (2009) Efficacy and Safety of great saphenous vein sclerotherapy using standardised polidocanol foam (ESAF): a randomised controlled multicentre clinical trial. Eur J Endovasc Vasc Surg 35(2):238–245

    Article  Google Scholar 

  • Rabe E, Pannier-Fischer F, Gerlach H, Breu FX et al (2004) Guidelines for sclerotherapy of varicose veins. Dermatol Surg 30(5):687–693

    CAS  PubMed  Google Scholar 

  • Rabe E (Hrsg) (2003) Grundlagen der Phlebologie, 3. erweiterte und vollständig überarbeitete Neuauflage. Viavital, Köln

    Google Scholar 

  • Rabe E, Breu FX et al (2018) Leitlinie Sklerosierungsbehandlung der Varikose. AWMF-Leitlinien-Register-Nr. 037–015

    Google Scholar 

  • Rabe E, Pannier-Fischer F, Gerlach H, Breu FX et al (2004) Guidelines for sclerotherapy of varicose veins (ICD 10: I83.0, I83.1, I83.2, and I83.9). Dermatol Surg 30(5):687–693

    Google Scholar 

  • Reddy P, Wickers J, Terry T, Lamont P, Moller J, Dormandy JA (1986) What is the correct period of bandaging following sclerotherapy? Phlebology 1:217–220

    Article  Google Scholar 

  • Remy W, Vogt H-J, Borelli S (1978) Embolia cutis medicamentosa – artige Hautnekrosen nach Sklerosierungsbehandlung. Phlebol Proktol 7:67–72

    Google Scholar 

  • Schadeck M (1993) Echo-sclerose de la grande Saphene. Phlebologie 46:673–682

    CAS  PubMed  Google Scholar 

  • Schadeck M (1996) (1996) Duplex-kontrollierte Sklerosierungsbehandlung der Vena saphena magna. Phlebologie 25:78–82

    Google Scholar 

  • Schadeck M, Allaert FA (1997) Résultats à long terme de la Sclérothérapie des Saphènes internes. Phlebologie 50(2):257–262

    Google Scholar 

  • Schelenz C (1932) 100 Jahre Injektionsspritze. Dtsch Med Wochenschr 58:543

    Article  Google Scholar 

  • Schneider W (1965) Contribution tot he history of the sclerosing treatment of varices and to ist anatomopatholigic study. Soc Fran de Phelbol 18:117

    CAS  Google Scholar 

  • Schultz-Ehrenburg U, Tourbier H (1984) Doppler-kontrollierte Verödungsbehandlung der Vena saphena magna. Phlebol u Proktol 13:117–122

    Google Scholar 

  • Sigg K (1952) The treatment of varicosities and accompanying complications. Angiology 3:355

    Article  CAS  PubMed  Google Scholar 

  • Sigg K (1978) Varicenbehandlung durch Sklerosierung. Langenbecks Arch Chir 347:231–234

    Article  CAS  PubMed  Google Scholar 

  • Sigg K (1976) Beinleiden, Entstehung und Behandlung. Springer, Berlin

    Google Scholar 

  • Stanley PRW, Bickerton DR, Campbell WB (1991) Injection sclerotherapy for varicose veins – a comparison of materials for applying local compression. Phlebology 6:37–39

    Article  Google Scholar 

  • Stemmer R (1990) Zur Geschichte der Sklerosierung aus französischer Sicht. Medicon , München

    Google Scholar 

  • Stücker M, Reich S, Hermes N et al (2006) Safety and efficiency of perilesional sclerotherapy in leg ulcer patients with postthrombotic syndrome and/or oral anticoagulation with Phenprocoumon. JDDG 4(9):734–738

    Article  PubMed  Google Scholar 

  • Sullivan LP, Quach G, Chapman T (2014) Retrograde mechanico-chemical endovenous ablation of infrageniculate great saphenous vein for persistent venous stasis ulcers. Phlebology 29:654–657

    Article  PubMed  Google Scholar 

  • Tang TY, Kam JW, Gaunt ME (2017) ClariVein® – early results from a large single-centre series of mechanochemical endo venous ablation for varicose veins. Phlebology 32(1):6–12

    Google Scholar 

  • Tazelaar DJ, Neumann HAM, de Roos KP (1999) Long cotton wool rolls as compression enhancers in macrosclerotherapy for varicose veins. Dermatol Surg 25(1):38–40

    Article  CAS  PubMed  Google Scholar 

  • Tessari L (2000) Nouvelle technique d’obtention de la scléro-mousse. Phlebologie 53:129

    Google Scholar 

  • Tessari L, Cavezzi A, Frullini A (2001) Preliminary experience with a new sclerosing foam in the treatment of varicose veins. Dermatol Surg 27:58–60

    CAS  PubMed  Google Scholar 

  • The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord (2015) 3: 2–7

    Google Scholar 

  • Tournay R (1972) La sclerose des Varices. L’Expansion, Paris

    Google Scholar 

  • Tournay R (1928) Les Varices. Pratique des injections sclerosantes. Maloine, Paris

    Google Scholar 

  • Villavicencio J, Pfeifer J, Lohr J, Goldman M, Cranley R, Spence R (1996) Sclerotherapy for varicose veins: Practice guidelines and sclerotherapy procedures. In: Glovicki P, Yao J (Hrsg.) Handbook of venous disorders. Chapmann & Hall Medical, London, S 37–54

    Google Scholar 

  • Vin F (1997) Principes de la Sclérothéraphie des Troncs Saphènes Internes. Phlebologie 50(2):229–234

    Google Scholar 

  • Vos CG, Ünlü C, Bosma J, van Vlijmen CJ, Nie JA, Schreve MA (2017) A systematic review and meta-analysis of two novel techniques of nonthermal endovenous ablation of the great saphenous vein. J Vasc Surg Venous Lymphat Disord 5(6):880–896

    Article  PubMed  Google Scholar 

  • Vun SV, Rashid ST, Blest NC, Spark JI (2015) Lower pain and faster treatment with mechanico-chemical endovenous ablation using ClariVein®. Phlebology 30(10):688–692

    Article  CAS  PubMed  Google Scholar 

  • De Waard MM, Der Kinderen DJ (2005) Duplex ultrasonography-guided foam sclerotherapy of incompetent perforator veins in a patient with bilateral venous leg ulcers. Dermatol Surg 31(5):580–583

    Article  PubMed  Google Scholar 

  • Weiss RA, Sadick NS, Goldman MP, Weiss MA (1999) Post-sclerotherapy compression: controlled comparative study of duration of compression and its effects on clinical outcome. Dermatol Surg 25:105–108

    Article  CAS  PubMed  Google Scholar 

  • Whiteley MS (2015) Glue, steam and clarivein – best practice techniques and evidence. Abstract Phlebology 30(2S):24–28

    Google Scholar 

  • Wildenhues B (2005) Endovenöse kathetergestützte Schaumsklerosierung. Phlebologie Germany 34(3):165–170

    Article  Google Scholar 

  • Witte ME, Reijnen MM, de Vries JP, Zeebregts CJ (2015) Mechanochemical endovenous occlusion of varicose veins using the clarivein® device. Surg Technol Int. 26:219–225

    PubMed  Google Scholar 

  • Wollmann JC (2004) The history of sclerosing foams. Dermatol Surg 30:694–703

    PubMed  Google Scholar 

  • Wuppermann T, Haas KH (1975) The effect of the sclerosing agent „Hydroxypolyaetoxydodecan“ on the coagulation potentials: in vitro investigations. VASA 4:45–53

    CAS  PubMed  Google Scholar 

  • Yamaki T, Nozaki M, Iwasaka S (2004) Comparative study of duplex-guided foam sclerotherapy and duplex-guided liquid sclerotherapy for the treatment of superficial venous insufficiency. Dermatol Surg 30(5):718–722

    PubMed  Google Scholar 

  • Yamaki T, Nozaki M, Sasaki K (2000) Color duplex-guided sclerotherapy for the treatment of venous malformations. Dermatol Surg 26(4):323–328

    Article  CAS  PubMed  Google Scholar 

  • Zipper SG (2000) Nervus peronäus-Schaden nach Varizensklerosierung mit Aethoxysklerol. Versicherungsmedizin 4:185–187

    Google Scholar 

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Authors and Affiliations

  1. Venen und Wundzentrum, Helios Cäcilien-Hospital Hüls, Krefeld, Deutschland

    Peter Waldhausen

  2. Facharzt für Allgemeinmedizin, Phlebologie, Venenzentrum am Tegernsee, Tegernsee, Deutschland

    Franz Xaver Breu

  3. Praxis PD Dr. Pannier, Bonn, Deutschland

    Eberhard Rabe

  4. Dermatologie/Phlebologie/Allergologie, Bonn, Deutschland

    Felizitas Pannier

  5. Abteilung Gefäßchirurgie, Bonifatius Hospital Lingen, Lingen, Deutschland

    Jörg Teßarek

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  1. Peter Waldhausen
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  2. Franz Xaver Breu
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  3. Eberhard Rabe
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  4. Felizitas Pannier
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  5. Jörg Teßarek
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Correspondence to Peter Waldhausen .

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  1. Klinik für Gefäßchirurgie und endovaskuläre Chirurgie, Krankenhaus Martha-Maria, Nürnberg, Deutschland

    Thomas Noppeney

  2. Dresden, Deutschland

    Helmut Nüllen

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Waldhausen, P., Breu, F.X., Rabe, E., Pannier, F., Teßarek, J. (2022). Chemische Ablationsverfahren. In: Noppeney, T., Nüllen, H. (eds) Varikose. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59117-8_22

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