Skip to main content
SpringerLink
Log in

Körperliche Komplikationen der Adipositas

  • Chapter
  • First Online:
Psychosoziale Aspekte der Adipositas-Chirurgie

  • 2071 Accesses

Zusammenfassung

Die gesundheitliche Bedeutung der Adipositas ist weniger durch die Adipositas per se als vielmehr durch Folgekrankheiten charakterisiert. Krankheiten können sich zum einen durch die große Körperfettmasse mit erhöhten statischen Belastungen und Verdrängung von Organen einstellen. Zum anderen sezerniert das vermehrte Fettgewebe eine Reihe von Produkten mit hormonellen, entzündlichen und anderen Eigenschaften, was zu metabolischen Komplikationen und Schädigungen an vielen Organen führen kann. Das Risiko für Folgekrankheiten hängt neben einer genetischen Prädisposition von Ausmaß und Dauer der Adipositas sowie von der Fettverteilung ab. Da sich bei nahezu allen adipösen Patienten im Laufe ihres Lebens Folgekrankheiten einstellen, sollten sie gemäß ihren Möglichkeiten informiert werden und die Adipositas als eine chronische Krankheit wahrnehmen. Die einzelnen Folgekrankheiten werden hinsichtlich Epidemiologie, Klinik, Pathophysiologie, Morbidität und Mortalität dargestellt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Alberti KGMM, Eckel RH, Grundy SM et al (2009) Harmonizing the metabolic syndrome. A joint meeting interim statement of the international diabetes federation task force on epidemiology and prevention. Circulation 120:1640–1645

    Article  CAS  PubMed  Google Scholar 

  • Andersen RE, Crespo CJ, Bartlett SJ, Bathon JM, Fontaine KR (2003) Relationship between body weight gain and significant knee, hip, and back pain in older Americans. Obes Res 11:1159–1162

    Article  PubMed  Google Scholar 

  • Ärnlöv J, Ingelsson E, Sundström J et al (2010) Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men. Circulation 121:230–236

    Article  PubMed  Google Scholar 

  • Aune D, Sen A, Norat T et al (2016) Body mass index, abdominal fatness and heart failure incidence and mortality: a systematic review and dose-response meta-analysis of prospective studies. Circulation 133:639–649

    Article  PubMed  Google Scholar 

  • Banim PJR, Luben RN, Bulluck H et al (2011) The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk). Eur J Gastroent Haematol 23:733–740

    Article  Google Scholar 

  • Bramlage P, Pittrow D, Wittchen HU, Kirch W, Boehler S, Lehnert H, Hoefler M, Unger T, Sharma AM (2004) Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. Am J Hypert 17:904–910

    Article  Google Scholar 

  • Canoy D, Boekholdt SM, Wareham N et al (2007) Body fat distribution and risk of coronary heart disease in men and women in the European prospective investigation into cancer and nutrition in Norfolk cohort. A population based prospective study. Circulation 116:2933–2943

    Article  PubMed  Google Scholar 

  • Castro-Anon O, Perez de Liano L, De la Fuente Sanchez S et al (2015) Obesity-hypoventilation syndrome: increased risk of death over sleep apnea. PLOS ONE do:https://doi.org/10.137/journal.pone0117808

  • Chang P, Friedenberg F (2014) Obesity & GERD. Gastroenterol Clin North Am 43:161–173

    Article  PubMed  Google Scholar 

  • Fabris de Souza SA, Faintuch J, Valezi AC et al (2013) Postural changes in morbidly obese patients. Obes Surg 15:1013–1016

    Article  Google Scholar 

  • Felson DT, Anderson JJ, Naimark A, Walker AM, Meenan RF (1988) Obesity and knee osteoarthritis. The Framingham study. Ann Int Med 109:18–24

    Article  CAS  PubMed  Google Scholar 

  • Field AE, Coakley EH, Must A et al (2011) Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med 161:1581–1586

    Article  Google Scholar 

  • Han TS, Schouten JSAG, Lean MEJ, Seidell JC (1997) The prevalence of low back pain and associations with body fatness, fat distribution and height. Int J Obes 21:600–607

    Article  CAS  Google Scholar 

  • Hashimoto Y, Matsudaira K, Sawada SS et al (2017) Obesity and low back pain: a retrospective cohort study of Japanese males. J Phys Ther Sci 29:978–983

    Article  PubMed  PubMed Central  Google Scholar 

  • Hauner H, Köster I, Schubert I (2007) Trends in der Prävalenz und ambulanten Versorgung von Menschen mit Diabetes mellitus im Zeitraum 1998 bis 2004: eine Analyse der Versichertenstichprobe AOK Hessen/KN Hessen. Dtsch Ärztebl 104:A2799–A2805

    Google Scholar 

  • Heitman J, Schneider H, Grote L, Peter JH (1993) Schlafapnoe und Adipositas. Adipositas 5:18–22

    Google Scholar 

  • Kenchaiah S, Evans JC, Levy D, Wilson PWF, Benjamin EJ, Larson MG, Kannel WB, Vasan RS (2002) Obesity and the risk of heart failure. N Engl J Med 347:305–313

    Article  PubMed  Google Scholar 

  • Khalid U, Ather S, Bavishi C et al (2014) Premorbid body-mass index and mortality after incident heart failure: the atherosclerosis risk in communities study. J Am Coll Cardiol 64:2743–2749

    Article  PubMed  PubMed Central  Google Scholar 

  • Kitade H, Chen G, Ni Y, Ota T (2017) Nonalcoholic fatty liver disease and insulin resistance: new insights and potentional new statements. Nutrients 9:387–399

    Article  PubMed Central  CAS  Google Scholar 

  • Kramer CK, Zinman B, Retnakaran R (2013) Are metabolically healthy overweight and obesity benign conditions? A systematic review and meta-analysis. Ann Int Med 159:758–769

    Article  PubMed  Google Scholar 

  • Landsberg L, Aronne LJ, Beilin LJ et al (2012) Obesity-related hypertension: pathogenesis, cardiovascular risk, and treatment – a position paper of the obesity society and the American society of hypertension. Obesity 21:8–24

    Article  PubMed  Google Scholar 

  • Lee SK, Kim SH, Cho G-Y et al (2013) Obesity phenotype and incident hypertension: a prospective community-based cohort study. J Hypertens 31:145–151

    Article  CAS  PubMed  Google Scholar 

  • Li L, Liu DW, Wang ZY et al (2016) Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21 cohort studies. Obes Res 17:510–519

    Article  CAS  Google Scholar 

  • Lu Y, Hajifathalian K, Ezzati M et al (2014) Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1,8 million participants. Lancet 15:970–983

    Google Scholar 

  • McGill HC, McMahan CA, Hederick EE, Zieske AW, Malcom GT, Tracy RE, Strong JP for the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group (2002) Obesity accelerates the progression of coronary atherosclerosis in young men. Circulation 105:2712–2718

    Google Scholar 

  • Meisinger C, Döring A, Thorand B et al (2006) Body fat distribution and risk of type 2 diabetes in the general population: are there differences between men and women? Am J Clin Nutr 84:483–489

    Article  CAS  PubMed  Google Scholar 

  • Messier SP (2008) Obesity and osteoarthritis: disease genesis and nonpharmalogical weight management. Rheum Dis Clin North Am 34:713–729

    Article  PubMed  PubMed Central  Google Scholar 

  • Moebus S, Hanisch J, Bramlage P et al (2008) Regional unterschiedliche Prävalenz des metabolischen Syndroms. Dtsch Ärztebl 105:207–213

    Google Scholar 

  • Nocon M, Labenz J, Willich SN (2006) Lifestyle factors and symptoms of gastrooesophageal reflux – a population-based study. Aliment Pharmacol Ther 23:169–174

    Article  CAS  PubMed  Google Scholar 

  • O’Neill S, O’Driscoll L (2015) Metabolic syndrome: a closer look at a growing epidemic and its associated pathologies. Obes Rev 16:1–12

    Article  PubMed  Google Scholar 

  • Radmard AR, Merat S, Kooraki S et al (2015) Gallstone disease and obesity: a population-based study on abdominal fat distribution and gender differences. Ann Hepatoloy 14:702–709

    Article  CAS  Google Scholar 

  • Reaven GM (1988) Role of insulin resistance in human disease. Diabetes 37:1495–1607

    Article  Google Scholar 

  • Reis JP, Powell-Wiley T, Hankinson AL et al (2013) Duration of abdominal obesity beginning in young adulthood and incident diabetes through middle age. Diabetes Care 36:1241–1247

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Reyes C, Leyland KM, Peat G et al (2016) Association between overweight and obesity and risk of clinically diagnosed knee, hip, and hand osteoarthritis: a population-based cohort study. Arthritis Rheumatol 68:1869–1875

    Article  PubMed  PubMed Central  Google Scholar 

  • Romero-Corral A, Montori VM, Somers VK, Korinek J, Thomas RJ, Allison TG, Mookadam F, Lopez-Jimenez F (2006) Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet 368:666–678

    Article  PubMed  Google Scholar 

  • Schipf S, Alte D, Völzke H et al (2010) Ergebnisse der Study of Health in Pomerania (SHIP). Diabetologia 5:161–168

    Article  Google Scholar 

  • Stamler J, Dyer AR, Shekelle RB (1993) Relationship of basal major risk factors in coronary and all-cause mortality, and to longeviti: findings from long-term follow-up Chicago cohorts. Cardiology 82:191–222

    Article  CAS  PubMed  Google Scholar 

  • Subak LL, Richter HE, Hunskaar S (2009) Obesity and urinary incontinence: epidemiology and clinical research update. J Urol 182:S2–S7

    Article  PubMed  PubMed Central  Google Scholar 

  • Velho S, Paccoud F, Waeber C et al (2010) Metabolically healthy obesity: different prevalences using different criteria. Eur J Clin Nutr 64:1043–1051

    Article  CAS  PubMed  Google Scholar 

  • Winter Y, Rohrmann S, Linseisen J et al (2010) Contribution of obesity and abdominal fat mass to risk of stroke and transient ischemic attacks. Stroke 39:3145–3151

    Article  Google Scholar 

  • Wirth A (2007) Adipositas – eine Krankheit? Cardiovasc 7:28–34

    Google Scholar 

  • Wirth A, Hauner H (Hrsg) (2008) Adipositas. Ätiologie, Folgekrankheiten, Diagnostik, Therapie, 3. Auf. Springer, Berlin

    Google Scholar 

  • Wirth A, Hauner H (Hrsg) (2013) Adipositas. Ätiologie, Folgekrankheiten, Diagnostik, Therapie, 4. Auf. Springer, Berlin

    Google Scholar 

  • Young T, Palta M, Dempsey J, Skatrud J, St Weber, Badr S (1993) The occurence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235

    Article  CAS  PubMed  Google Scholar 

  • Zhang TT, Liu YL, Zhao JJ et al (2018) Obesity as a risk factor for low back pain: a meta-analysis. Clin Spine Surg 31:22–27 (Epub ahead of print)

    Google Scholar 

  • Zheng H, Chen C (2015) Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies. BMJ Open 5:e007568doi10.1136/bmjopen-2014-007568 2015

    Google Scholar 

  • Zhou ZY, Chen HL, Liu F (2014) Body mass index and knee osteoarthritis risk: a dose-response meta-analysis. Obesity 22:2180–2185

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Bad Rothenfelde, Deutschland

    Alfred Wirth

Authors
  1. Alfred Wirth
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alfred Wirth .

Editor information

Editors and Affiliations

  1. Klinik für Psychosomatik und Psychotherapie, Medizinische Hochschule Hannover, Hannover, Deutschland

    Martina de Zwaan

  2. Klinik für Psychosomatische Medizin und Psychotherapie, LWL-Universitätsklinikum der Ruhr-Universität Bochum, Bochum, Deutschland

    Stephan Herpertz

  3. Abteilung für Psychosomatische Medizin und Psychotherapie, Medizinische Universitätsklinik Tübingen, Tübingen, Deutschland

    Stephan Zipfel

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Wirth, A. (2019). Körperliche Komplikationen der Adipositas. In: de Zwaan, M., Herpertz, S., Zipfel, S. (eds) Psychosoziale Aspekte der Adipositas-Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57364-8_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-57364-8_2

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-57363-1

  • Online ISBN: 978-3-662-57364-8

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation