Skip to main content

Prävention im Alter – Was ist gesichert?

  • Chapter
  • First Online:

Zusammenfassung

Herz- und Kreislauferkrankungen sind die häufigsten Todesursachen in Deutschland. Da das Alter für die meisten Herz- und Kreislauferkrankungen ein eigenständiger und unabhängiger Risikofaktor ist, sind alte Menschen hiervon besonders betroffen, wobei das Risiko mit steigendem Lebensalter sogar exponentiell ansteigt. Dies gilt v. a. für den Bluthochdruck, der wiederum der wichtigste Risikofaktor für die koronare Herzkrankheit (KHK; Herzkranzgefäßerkrankung), die Herzinsuffizienz (Herzschwäche) sowie den Schlaganfall ist. Ein weiterer Risikofaktor ist der Diabetes mellitus, der insbesondere das Risiko für die Entwicklung einer Herzinsuffizienz erhöht, aber auch für die anderen genannten Krankheiten von Bedeutung ist. Herzinsuffiziente Patienten wiederum haben eine höhere Wahrscheinlichkeit, Diabetes zu entwickeln.

This is a preview of subscription content, log in via an institution.

Buying options

eBook
USD   19.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   29.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Literatur

  • Aggarwal NT, Wilson RS et al (2014) Perceived stress and change in cognitive function among adults 65 years and older. Psychosom Med 76(1):80–85

    Article  Google Scholar 

  • van Agtmaal MJM, Houben A et al (2017) Association of microvascular dysfunction with late-life depression: a systematic review and meta-analysis. JAMA Psychiat 74(7):729–739

    Article  Google Scholar 

  • Bartl, R. (2006) Blickpunkt Ernährung – folgenreiches Fehlverhalten von Jung bis Alt https://www.osd-ev.org/osteoporose/bni/blickpunkt-ernaehrung/

  • Bauer JM (2016) Sarkopenie und Frailty 2016. Z Gerontol Geriat 49:565–566

    Article  Google Scholar 

  • Bellou V, Belbasis L et al (2017) Systematic evaluation of the associations between environmental risk factors and dementia: an umbrella review of systematic reviews and meta-analyses. Alzheimers Dement 13(4):406–418

    Article  Google Scholar 

  • Bennett DA, Wilson RS et al (2013) Selected findings from the religious orders study and rush memory and aging project. J Alzheimers Dis 33(Suppl 1):S397–S403

    Google Scholar 

  • Brummett BH, Austin SB et al (2013) Long-term impact of caregiving and metabolic syndrome with perceived decline in cognitive function 8 Years later: a pilot study suggesting important avenues for future research. Open J Med Psychol 2(1):23–28

    Article  Google Scholar 

  • Chang KP et al (2004) Incidence of hip and other osteoporotic fractures in elderly men and women: dubbo osteoporosis. J Bone Miner 19(4):532–536

    Google Scholar 

  • Chien LY, Chu H et al (2011) Caregiver support groups in patients with dementia: a meta-analysis. Int J Geriatr Psychiatry 26(10):1089–1098

    Article  Google Scholar 

  • Collard RM, Arts M, Comijs HC et al (2015) The role of frailty in the association between depression and somatic comorbidity: results from baseline data of an ongoing prospective cohort study. Int J Nurs Stud 52:188–196

    Article  Google Scholar 

  • Delbaere K et al (2010) Determinant of disparities between perceived and physiological risk of falling among elderly people: cohort study. BMJ 341:c4165. https://doi.org/10.1136/bmj

    Article  Google Scholar 

  • Dennison EM, Sayer AA, Cooper C (2017) Epidemiology of sarcopenia and insight into possible therapeutic targets. Nat Rev Rheumatol 13:340–347

    Article  Google Scholar 

  • Deutscher Gesundheitsbericht Diabetes 2018 und 2019

    Google Scholar 

  • Edmonds S et al (2017) Understanding preferences for osteoporosis information to develop an osteoporosis patient education brochure. Perm J 21:16–24

    Article  Google Scholar 

  • Epidemiology Study (2004) J Bone Miner Res 19:532–536

    Article  Google Scholar 

  • Erickson KI, Voss MW et al (2011) Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci USA 108(7):3017–3022

    Article  Google Scholar 

  • Feeney, J., M. O’Sullivan, et al. (2018). Change in perceived stress and 2-year change in cognitive function among older adults: the irish longitudinal study on ageing. Stress Health 34(3):403–410

    Article  Google Scholar 

  • Fellgiebel A, Hautzinger M (Hrsg) (2017) Altersdepression: ein interdisziplinäres Handbuch. Springer, Berlin

    Google Scholar 

  • Forbes SC, Holroyd-Leduc JM et al (2015) Effect of nutrients, dietary supplements and vitamins on cognition: a systematic review and meta-analysis of randomized controlled trials. Can Geriatr J 18(4):231–245

    Article  Google Scholar 

  • Fried LP et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56(3):M146–M156

    Article  Google Scholar 

  • Fuchs J et al (2016) Prävalenz von körperlicher Gebrechlichkeit (Frailty). In: Robert Koch Institut (Hrsg) Faktenblatt zu DEGS1: Studie zur Gesundheit Erwachsener in Deutschland (2008–2011). RKI, Berlin. (www.DEGS-Studie.de)

    Google Scholar 

  • Gilbody S, Lewis H et al (2017) Effect of collaborative care vs usual care on depressive symptoms in older adults with subthreshold depression: the CASPER randomized clinical trial. JAMA 317(7):728–737

    Article  Google Scholar 

  • von Haehling S, Morley JE, Anker SD (2010) An overview of sarcopenia: facts and numbers on prevalence and clinical impact. J Cachexia Sarcopenia Muscle 1:129–133

    Article  Google Scholar 

  • Hall CB, Lipton RB et al (2009) Cognitive activities delay onset of memory decline in persons who develop dementia. Neurology 73(5):356–361

    Article  Google Scholar 

  • Hardman RJ, Kennedy G et al (2016) Adherence to a mediterranean-style diet and effects on cognition in adults: a qualitative evaluation and systematic review of longitudinal and prospective trials. Front Nutr 3:22

    Article  Google Scholar 

  • Hautzinger M, Dykierek P et al (2017) Psychotherapeutic approaches for treatment of the elderly. Nervenarzt 88(11):1213–1220

    Article  Google Scholar 

  • Head D, Bugg JM et al (2012) Exercise engagement as a moderator of the effects of APOE genotype on amyloid deposition. Arch Neurol 69(5):636–643

    Article  Google Scholar 

  • Kirkendall DT, Garrett WE (1998) The effects of aging and training on skeletal muscle. Am J Sports Med 26:598–602

    Article  Google Scholar 

  • Klotz T (2002) Urologe [A] 41:315. https://doi.org/10.1007/s00120-002-0210-6

    Article  Google Scholar 

  • Langa KM, Larson EB et al (2017) A Comparison of the prevalence of dementia in the United States in 2000 and 2012. JAMA Intern Med 177(1):51–58

    Article  Google Scholar 

  • Lazarov O, Robinson J et al (2005) Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120(5):701–713

    Article  Google Scholar 

  • Leitlinie des Dachverbandes der Deutschsprachigen Wissenschaftlichen Osteologischen Gesellschaften e. V. 2017

    Google Scholar 

  • Linnemann A, Fellgiebel A (2017) Psychotherapy with mild cognitive impairment and dementia. Nervenarzt 88(11):1240–1245

    Article  Google Scholar 

  • Livingston G, Sommerlad A et al (2017) Dementia prevention, intervention, and care. Lancet 390(10113):2673–2734

    Article  Google Scholar 

  • Meng XF, Yu JT et al (2014) Midlife vascular risk factors and the risk of Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimers Dis 42(4):1295–1310

    Article  Google Scholar 

  • Moon B, Kim S et al (2017) Depressive symptoms are associated with progression to dementia in patients with amyloid-positive mild cognitive impairment. J Alzheimers Dis 58(4):1255–1264

    Article  Google Scholar 

  • Morley JE, Vellas B, van Kann GA, Anker SD, Bauer JM, Bernabei R, Cedari M, Chumela WC, Doehner W, Evans J, Friedl LP, Guralnik JM, Katz PR, Mamstrom TK, McCarter RJ, Gutierrez Robledo LM, Rockwood K, von Haehling S, Vandewoude MF, Walston J (2013) Frailty consensus: a call to action. J Am Med Dir Assoc 214:392–397

    Article  Google Scholar 

  • Nationale Versorgungs Leitlinie Prävention und Therapie von Netzhautkomplikationen bei Diabetes, 2. Aufl., Version 2, 2015, AWMF-Registernummer: nvl-001b

    Google Scholar 

  • Neuropathology Group. Medical Research Council Cognitive Function and Aging Study (2001) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Lancet 357(9251):169–175

    Article  Google Scholar 

  • Nordberg A, Carter SF et al (2013) A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease. Eur J Nucl Med Mol Imaging 40(1):104–114

    Article  Google Scholar 

  • Phillips P (1986) Grip strenght, mental performance and nutritional status as indicators of mortality risk among female geriatric patients. Age Ageing 15:53–56

    Article  Google Scholar 

  • Reuben D et al (2017) The Strategies to reduce injuries and develop confidence in elders intervention: falls risk factor assessment and management, patient engagement, and nurse co-management. American Geriatrics Society 65:2733–2739

    Article  Google Scholar 

  • Ritt M, Gassmann KG, Sieber CC (2016) Significance of frailty für predicting adveres clinical outcomes in different patient groups with specific medical conditions. Z Gerontol Geriatr 49:567–572

    Article  Google Scholar 

  • Rosenberg ICH (1997) Sarcopenia: origins and clinicla relevance. J Nutr 127(5 Suppl):990s–991s

    Article  Google Scholar 

  • Ruscheweyh R, Willemer C et al (2011) Physical activity and memory functions: an interventional study. Neurobiol Aging 32(7):1304–1319

    Article  Google Scholar 

  • Russell-Williams J, Jaroudi W et al (2018) Mindfulness and meditation: treating cognitive impairment and reducing stress in dementia. Rev Neurosci

    Google Scholar 

  • Sahni S et al (2017) Dairy intake is protective against bone loss in older Vitamin D supplement users: the framingham study. J Nutr 147:645–652

    Article  Google Scholar 

  • Schlosser M et al (2017) Nephropathie bei Diabetes. Diabetologie 12(Suppl 2):115–120

    Google Scholar 

  • Schoene D et al (2017) Sklettmuskuläre Faktoren, Sarkopenie und Stürze im Alter. Z Gerontol Geriat. https://doi.org/10.1007/s00391-017-1283-6

    Article  Google Scholar 

  • Singh-Manoux A, Dugravot A et al (2017) Trajectories of depressive symptoms before diagnosis of dementia: a 28-Year follow-up study. JAMA Psychiatry 74(7):712–718

    Article  Google Scholar 

  • Smith PJ, Blumenthal JA et al (2010) Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med 72(3):239–252

    Article  Google Scholar 

  • Sofi F, Valecchi D et al (2011) Physical activity and risk of cognitive decline: a meta-analysis of prospective studies. J Intern Med 269(1):107–117

    Article  Google Scholar 

  • Spira D (2013) Dissertation Charite. Untersuchungen zum Zusammenhang zwischen Vitamin D-Mangel, Sarkopenie und Frailty-Syndrom am Beispiel einer Stichprobe in BASE-II. Berliner Altersstudie 2

    Google Scholar 

  • Srivastava M et al (2002) Osteoporosis in elderly: prevention and treatment. Clin Geriatr Med 18:529–555

    Article  Google Scholar 

  • Stern Y (2009) Cognitive reserve. Neuropsychologia 47(10):2015–2028

    Article  Google Scholar 

  • Sternberg SA, Wershof SA, Karunananthan S, Bergman H, Mark CA (2011) The identification of frailty: a systematic literature review. J Am Geriatr Soc 59:2129–2138

    Article  Google Scholar 

  • Sun X, Steffens DC et al (2008) Amyloid-associated depression: a prodromal depression of Alzheimer disease? Arch Gen Psychiatry 65(5):542–550

    Article  Google Scholar 

  • Teipel S, Drzezga A et al (2015) Multimodal imaging in Alzheimer’s disease: validity and usefulness for early detection. Lancet Neurol 14(10):1037–1053

    Article  Google Scholar 

  • Valls-Pedret C, Sala-Vila A et al (2015) Mediterranean diet and age-related cognitive decline: a randomized clinical trial. JAMA Intern Med 175(7):1094–1103

    Article  Google Scholar 

  • Van Orden K, Deming C (2017) Late-life suicide prevention strategies: current status and future directions. Curr Opin Psychol 22:79–83

    Article  Google Scholar 

  • Vaughan L, Corbin AL et al (2015) Depression and frailty in later life: a systematic review. Clin Interv Aging 10:1947–1958

    Article  Google Scholar 

  • Vetter C (2010) Sturzneigung älterer Menschen: die Angst vor Stürzen erhöht das Risiko zu fallen. Dtsch Arztebl 107(46):A-2289/B-1979/C-1943

    Google Scholar 

  • Wirth M, Villeneuve S et al (2014) Gene-environment interactions: lifetime cognitive activity, APOE genotype, and beta-amyloid burden. J Neurosci 34(25):8612–8617

    Article  Google Scholar 

  • Wolf D, Fischer FU et al (2014) Structural integrity of the corpus callosum predicts long-term transfer of fluid intelligence-related training gains in normal aging. Hum Brain Mapp 35(1):309–318

    Article  Google Scholar 

  • Wong SYS, Sun YY et al (2018) Treating subthreshold depression in primary care: a randomized controlled trial of behavioral activation with mindfulness. Ann Fam Med 16(2):111–119

    Article  Google Scholar 

  • Wu YT, Fratiglioni L et al (2016) Dementia in western Europe: epidemiological evidence and implications for policy making. Lancet Neurol 15(1):116–124

    Article  Google Scholar 

Weiterführende Literatur

  • Deutsches Ärzteblatt 116; Heft 23-24; 10.06.2019; C 966-967

    Google Scholar 

  • Nationale VersorgungsLeitlinie Nierenerkrankungen bei Diabetes im Erwachsenenalter, 1. Aufl., Version 5, 2010, letzte Änderung Mai 2013, AWMF-Registernummer: nvl-001d

    Google Scholar 

  • NVL (Nationale VersorgungsLeitlinie) Therapie des Typ-2-Diabetes, 1. Aufl., Version 3, August 2013, letzte Änderung April 2014, AWMF-Registernummer: nvl-001g

    Google Scholar 

  • S2k-Leitlinie Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Alter der Deutschen Diabetes Gesellschaft (DDG), 2. Aufl., 2018, AWMF-Registernummer: 057-017

    Google Scholar 

  • PatientenLeitlinie zur Nationalen VersorgungsLeitlinie „Typ-2-Diabetes Prävention und Behandlungsstrategien für Fußkomplikationen“, Version 01.01, 2008

    Google Scholar 

  • PatientenLeitlinie zur Nationalen VersorgungsLeitlinie „Neuropathie bei Diabetes im Erwachsenenalter“, 1. Aufl., Version 1.0, 2014

    Google Scholar 

  • PatientenLeitlinie zur Nationalen VersorgungsLeitlinie „Therapie des Typ-2-Diabetes“, 1. Aufl., Version 1, Juni 2015

    Google Scholar 

  • PatientenLeitlinie zur Nationalen VersorgungsLeitlinie „Diabetes Schäden an der Netzhaut: vorbeugen und behandeln“, 2. Aufl., Version 2, 2016

    Google Scholar 

  • Zeyfang A et al (2017) Diabetes mellitus im Alter. Diabetologie 12(Suppl 2):203–211

    Google Scholar 

  • Ziegler D et al (2017) Diabetische Neuropathie. Diabetologie 12(Suppl 2):101–114

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Roland Hardt .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Hardt, R., Seibert-Grafe, M., Fellgiebel, A., Wiechelt, J., Schulz, G., Thomczyk, S. (2019). Prävention im Alter – Was ist gesichert?. In: Hardt, R., Junginger, T., Seibert-Grafe, M. (eds) Prävention im Alter – Gesund und fit älter werden. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56788-3_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-56788-3_2

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-56787-6

  • Online ISBN: 978-3-662-56788-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics