Wide-Field Surface Plasmon Resonance Microscopy for In-Situ Characterization of Nanoparticle Suspensions

  • Shavkat Nizamov
  • Vladimir M. MirskyEmail author


During the past two decades, nanomaterials have had an enormous diversity of applications in different industrial fields and fundamental research. Some of these nanomaterials are specifically engineered to exhibit unique optical, electrical, or other physical or chemical characteristics. Owing to these attributes, the products containing various engineered nanoparticles (NP) cover large segments of the market from clothing to electronics and healthcare products [1]. The rapid development of nanotechnologies, their industrial applications, and related nanosafety concerns demand sensitive analytical methods for the identification and analysis of nanoparticles (NPs) in very different media [2]. In the same time, there are serious concerns on possible toxicity of nanoparticles for humans and environment [3]. Engineered NPs (ENPs) have to be analyzed not only during their production, in pure and concentrated form, but also at trace concentrations in environment, drinking water and food, healthcare and pharmacological products, biological fluids, etc. Ideally, such a technique should provide a possibility to detect NPs at the level of single particles and deliver information on their concentration, core and surface chemical composition, size, and shape [2–4].



The work was supported by FP7 EC Project “NANODETECTOR” (FP7-NMP-2011-SME-5, #280478) and Thermo-SPR (MWFK). We are grateful to all project partners for discussions and suggestions. An assistance of Dr. K. Tonder and V. Scherbahn is acknowledged.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Biotechnology, Department of NanobiotechnologyBrandenburg University of Technology Cottbus-SenftenbergSenftenbergGermany

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