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POCT - Patientennahe Labordiagnostik pp 163–174Cite as

Diagnostik kardiovaskulärer Krankheiten

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Zusammenfassung

Der bevorzugte Biomarker in der Herzinfarktdiagnostik ist das quantitativ im Serum gemessene kardiale Troponin (cTn) wegen seiner Gewebespezifität. Bei Verwendung hochsensitiver cTn-Assays wird die Bestimmung weiterer Marker wie Myoglobin, CK-MB Masse, FABP nicht empfohlen, da diese Biomarker keinen diagnostischen Zusatznutzen bringen. Hochsensitive cTn-Assays werden bislang von zwei POCT-Benchtop-Geräten angeboten. Für die labormedizinische Begleitung der chronischen Herzinsuffizienz stehen heute mit dem BNP und dem NT-pro-BNP Marker zur Verfügung, deren Einsatz von Europäischen und Amerikanischen Fachgesellschaften für Screening und Diagnostik der Herzinsuffizienz empfohlen wird. POCT-Methoden zur Messung sind bereits entwickelt worden.

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Author information

Authors and Affiliations

  1. Thoraxklinik am Universitätsklinikum Heidelberg, Amalienstraße 5, 69126, Heidelberg, Deutschland

    Prof. Dr. med. Evangelos Giannitsis

  2. Medizinische Klinik (Kardiologie), Charité – Universitätsmedizin Berlin, Schumannstraße 20/21, 10098, Berlin, Deutschland

    Prof. Dr. Ingolf Schimke

  3. Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der TU München, Ismaninger Straße 22, 81675, München, Deutschland

    Prof. Dr. Peter B. Luppa

  4. Institut für Laboratoriumsmedizin, HELIOS Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125, Berlin, Deutschland

    Prof. Dr. Dirk Peetz

Authors
  1. Prof. Dr. med. Evangelos Giannitsis
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  2. Prof. Dr. Ingolf Schimke
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  3. Prof. Dr. Peter B. Luppa
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  4. Prof. Dr. Dirk Peetz
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Editor information

Editors and Affiliations

  1. TU München Klinikum rechts der Isar, München, Deutschland

    Peter B. Luppa

  2. Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland

    Ralf Junker

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Giannitsis, E., Schimke, I., Luppa, P.B., Peetz, D. (2017). Diagnostik kardiovaskulärer Krankheiten. In: Luppa, P., Junker, R. (eds) POCT - Patientennahe Labordiagnostik. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54196-8_17

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