Subchondral Bone: Healthy Soil for the Healthy Cartilage



Role of subchondral bone in the natural healing of the cartilage has been largely ignored during the last few decades; whereas the cartilage repair science evolved continuously. Clinicians and scientists were aware of the various properties of the subchondral bone; like nutrition to the cartilage, load sharing with the cartilage and as a constant supplier of chondroblasts, pluripotent cells and the growth factors to the cartilage. Various conditions like osteochondritis dissecans, osteonecrosis, bone marrow oedema in chondral injuries etc constantly indicated that the subchondral bone and the cartilage are one single unit-the osteochondral unit. However, there was an unintended neglect about the role of these important properties of the subchondral bone in the natural repair of the cartilage. The subchondral bone and the overlying cartilage, work as one integral unit and help each other in maintaining the biomechanical equilibrium. The relation between both the components is like a soil-plant relationship where none can survive without the other part. A proper attention to the subchondral bone is thus important to maintain a healthy cartilaginous tissue under physiological stresses and to regenerate a healthy cartilage in case of the cartilage damage.


Subchondral Bone Cartilage Repair Natural Healing Physiological Limit Calcify Cartilage 
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© ISAKOS 2017

Authors and Affiliations

  1. 1.Saumya Orthocare: Centre for Advanced Surgeries of the Knee JointAhmedabadIndia
  2. 2.Department of PathologySmt NHL Municipal Medical CollegeAhmedabadIndia
  3. 3.Department of Orthopaedic Surgery, Graduate School of Biomedical SciencesHiroshima UniversityHiroshimaJapan

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