Abstract
A bleb leak, early or late, is a potentially vision-threatening complication of glaucoma-filtering surgery.
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References
AGIS Investigators. The Advanced Glaucoma Intervention Study (AGIS): 11. Risk factors for failure of trabeculectomy and argon laser trabeculoplasty. Am J Ophthalmol. 2002;134:481–98.
Al-Shahwan S, Al-Torbak AA, Al-Jadaan I, et al. Long-term follow up of surgical repair of late bleb leaks after glaucoma filtering surgery. J Glaucoma. 2006;15:432–6.
Asrani SG, Wilensky JT. Management of bleb leaks after glaucoma filtering surgery. Use of autologous fibrin tissue glue as an alternative. Ophthalmology. 1996;103:294–8.
Blok MD, Kok JH, van Mil C, et al. Use of the megasoft bandage lens for treatment of complications after trabeculectomy. Am J Ophthalmol. 1990;110:264–8.
Budenz DL, Barton K, Tseng SC. Amniotic membrane transplantation for repair of leaking glaucoma filtering blebs. Am J Ophthalmol. 2000;130:580–8.
Budenz DL, Chen PP, Weaver YK. Conjunctival advancement for late-onset filtering bleb leaks: indications and outcomes. Arch Ophthalmol. 1999;117:1014–9.
Burnstein A, WuDunn D, Ishii Y, et al. Autologous blood injection for late-onset filtering bleb leak. Am J Ophthalmol. 2001;132:36–40.
Burnstein AL, WuDunn D, Knotts SL, et al. Conjunctival advancement versus nonincisional treatment for late-onset glaucoma filtering bleb leaks. Ophthalmology. 2002;109:71–5.
CAT-152 Trabeculectomy Study Group, Grehn F, Holló G, et al. Factors affecting the outcome of trabeculectomy: an analysis based on combined data from two phase III studies of an antibody to transforming growth factor beta2, CAT-152. Ophthalmology. 2007;114:1831–8.
Catoira Y, Wudunn D, Cantor LB. Revision of dysfunctional filtering blebs by conjunctival advancement with bleb preservation. Am J Ophthalmol. 2000;130:574–9.
Chen PP, Gedde SJ, Budenz DL, et al. Outpatient treatment of bleb infection. Arch Ophthalmol. 1997;115:1124–8.
DeBry PW, Perkins TW, Heatley G, et al. Incidence of late-onset bleb-related complications following trabeculectomy with mitomycin. Arch Ophthalmol. 2002;120:297–300.
Fluorouracil Filtering Surgery Study Group. Five-year follow-up of the Fluorouracil Filtering Surgery Study. Am J Ophthalmol. 1996;121:349–66.
Francis BA, Du LT, Najafi K, et al. Histopathologic features of conjunctival filtering blebs. Arch Ophthalmol. 2005;123:166–70.
Geyer O. Management of large, leaking, and inadvertent filtering blebs with the neodymium: YAG laser. Ophthalmology. 1998;105:983–7.
Greenfield DS, Liebmann JM, Jee J, et al. Late-onset bleb leaks after glaucoma filtering surgery. Arch Ophthalmol. 1998;116:443–7.
Harris LD, Yang G, Feldman RM, et al. Autologous conjunctival resurfacing of leaking filtering blebs. Ophthalmology. 2000;107:1675–80.
Henderson HW, Ezra E, Murdoch IE. Early postoperative trabeculectomy leakage: incidence, time course, severity, and impact on surgical outcome. Br J Ophthalmol. 2004;88:626–9.
Hutchinson AK, Grossniklaus HE, Brown RH, et al. Clinicopathologic features of excised mitomycin filtering blebs. Arch Ophthalmol. 1994;112:74–9.
Jampel HD, Quigley HA, Kerrigan-Baumrind LA, et al. Risk factors for late-onset infection following glaucoma filtration surgery. Arch Ophthalmol. 2001;119:1001–8.
Jones E, Clarke J, Khaw PT. Recent advances in trabeculectomy technique. Curr Opin Ophthalmol. 2005;16:107–13.
Kee C, Hwang JM. Amniotic membrane graft for late-onset glaucoma filtering leaks. Am J Ophthalmol. 2002;133:834–5.
La Borwit SE, Quigley HA, Jampel HD. Bleb reduction and bleb repair after trabeculectomy. Ophthalmology. 2000;107:712–8.
Lamping KA, Bellows AR, Hutchinson BT, et al. Long-term evaluation of initial filtration surgery. Ophthalmology. 1986;93:91–101.
Leen MM, Moster MR, Katz LJ, et al. Management of overfiltering and leaking blebs with autologous blood injection. Arch Ophthalmol. 1995;113:1050–5.
Lin AP, Chung JE, Zhang KS, Chang MM, Orengo-Nania S, Gross RL, Chang PT. Outcomes of surgical bleb revision for late-onset bleb leaks after trabeculectomy. J Glaucoma. 2013;22:21–5.
Lynch MG, Roesch H, Brown RH. Remodeling filtering blebs with the neodymium: YAG laser. Ophthalmology. 1996;103:1700–5.
O’Connor DJ, Tressler CS, Caprioli J. A surgical method to repair leaking filtering blebs. Ophthalmic Surg. 1992;23:336–8.
Palmberg P, Zacchei AC. Compression sutures – a new treatment for leaking or painful filtering blebs. Invest Ophthalmol Vis Sci. 1996;37:S444.
Panday M, Shantha B, George R, Boda S, Vijaya L. Outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. J Glaucoma. 2011;20:392–7.
Parrish RK, Schiffman JC, Feuer WJ, et al. Prognosis and risk factors for early postoperative wound leaks after trabeculectomy with and without 5-fluorouracil. Am J Ophthalmol. 2001;132:633–40.
Radakrishnan S, Quigley HA, Jampel HD, Friedman DS, Ahmad SI, Congdon NG, McKinnon S. Outcomes of surgical bleb revision for complications of trabeculectomy. Ophthalmology. 2009;116:1713–8.
Schnyder CC, Shaarawy T, Ravinet E, et al. Free conjunctival autologous graft for bleb repair and bleb reduction after trabeculectomy and nonpenetrating filtering surgery. J Glaucoma. 2002;11:10–6.
Sethi P, Patel RN, Goldhardt R, Ayyala RS (2014) Conjunctival advancement with subconjunctival amniotic membrane draping technique for leaking cystic blebs. J Glaucoma. 2016;25:188–92
Shields MB, Scroggs MW, Sloop CM, et al. Clinical and histologic observations concerning hypotony after trabeculectomy with mitomycin C. Am J Ophthalmol. 1993;116:673–83.
Smith MF, Magauran III RG, Betchkal J, et al. Treatment of postfiltration bleb leaks with autologous blood. Ophthalmology. 1995;102:868–71.
Soltau JB, Rothman RF, Budenz DL, et al. Risk factors for glaucoma filtering bleb infections. Arch Ophthalmol. 2000;118:338–42.
Song A, Scott IU, Flynn Jr HW, et al. Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes. Ophthalmology. 2002;109:985–91.
Tannenbaum DP, Hoffman D, Greaney MJ, et al. Outcomes of bleb excision and conjunctival advancement for leaking or hypotonous eyes after glaucoma filtering surgery. Br J Ophthalmol. 2004;88:99–103.
Wadhwani RA, Bellows AR, Hutchinson BT. Surgical repair of leaking filtering blebs. Ophthalmology. 2000;107:1681–7.
Wilson MR, Kotas-Neumann R. Free conjunctival patch for repair of persistent late bleb leak. Am J Ophthalmol. 1994;117:569–74.
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Chen, P.P. (2016). Complications: Bleb Leaks. In: Giaconi, J., Law, S., Nouri-Mahdavi, K., Coleman, A., Caprioli, J. (eds) Pearls of Glaucoma Management. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49042-6_60
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