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ART for Antiaging

  • Qing-Ping ZengEmail author
Chapter
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

ART can mimic CR to extend yeast lifespan, during which both ART and CR-triggered NO can activate antioxidative responses and convert the metabolic pattern from biosynthesis to degradation. ART also mimics CR to compromise mouse telomere shortening by upregulating antioxidative enzymes for effective ROS scavenging, which is followed by the alleviation of DNA damage and downregulation of tumor suppressors. This is the first time for having found ART exerting an antiaging role.

Keywords

Antioxidation ART CR Lifespan Telomere 

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Copyright information

© The Author(s) 2015

Authors and Affiliations

  1. 1.Tropical Medicine InstituteGuangzhou University of Chinese MedicineGuangzhouChina

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