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ART for Antibacterial Infection

  • Qing-Ping ZengEmail author
Chapter
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

In Gram positive bacteria, bNOS-derived NO confers the protection of bacteria from environmental stress such as antibiotic challenges. ART can exert an antibiotic sensitizing role through inhibiting bNOS and CAT. Either in vivo or in vitro, ART can increase the bacteriocidal activity of antibiotics by abrogating the beneficial NO and enhancing the harmful H2O2, demonstrating a potential role in combating multidrug resistant bacteria.

Keywords

ART Bacteria bNOS H2O2 Multidrug resistance NO 

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Copyright information

© The Author(s) 2015

Authors and Affiliations

  1. 1.Tropical Medicine InstituteGuangzhou University of Chinese MedicineGuangzhouChina

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