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ART for Antitumor

  • Qing-Ping ZengEmail author
Chapter
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

ART acts on tumor cells differentially by the threshold concentrations. High-dose ART kills tumor cells upon the inhibition of NOS, whereas low-dose ART benefits tumor propagation due to induce cytoprotective NO production. Pro-oxidants that antagonize antioxidants can potentiate ART’s antitumor capacity. The combination of ART with pro-oxidants should provide an effective solution to the chemotherapy of multidrug resistant tumors.

Keywords

ART NOS Pro-oxidants Chemotherapy Sensitization 

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Copyright information

© The Author(s) 2015

Authors and Affiliations

  1. 1.Tropical Medicine InstituteGuangzhou University of Chinese MedicineGuangzhouChina

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