Zusammenfassung
Bei uns Menschen ist die Großhirnrinde viel stärker entwickelt als bei allen anderen Säugetieren. Dank des sehr großen Frontallappens unseres Gehirns können wir bewusst denken und planen und uns damit eine Existenz schaffen, die ganz und gar unserem bewussten Willen zu unterliegen scheint. Bei anderen Säugetieren werden nicht nur die Körperfunktionen, sondern auch das Verhalten – beispielsweise im Rahmen der unterschiedlichsten Beziehungen – überwiegend durch unbewusste Prozesse gesteuert, die in älteren Hirnarealen lokalisiert sind.
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Acheson D, Feifel D, de Wilde S, McKinney R, Lohr J, Risbrough V (2013) The effect of intranasal oxytocin treatment on conditioned fear extinction and recall in a healthy human sample. Psychopharmacology (Berl) 229(1):199–208
Aoki Y, Yahata N, Watanabe T, Takano Y, Kawakubo Y, Kuwabara H, Yamasue H (2014) Oxytocin improves behavioural and neural deficits in inferring others’ social emotions in autism. Brain 137(Pt 11):3073–3086
Aoki Y, Watanabe T, Abe O, Kuwabara H, Yahata N, Takano Y, Yamasue H (2015) Oxytocin’s neurochemical effects in the medial prefrontal cortex underlie recovery of task-specific brain activity in autism: a randomized controlled trial. Mol Psychiatry 20(4):447–453
Boucher M, Nimrod CA, Tawagi GF, Meeker TA, Rennicks White RE, Varin J (2004) Comparison of carbetocin and oxytocin for the prevention of postpartum hemorrhage following vaginal delivery: a double-blind randomized trial. J Obstet Gynaecol Can 26:481–488
Burnham TC (2007) High-testosterone men reject low ultimatum game offers. Proc R Soc Biol Sci 274:2327–2330
Bystrova K, Ivanova V, Edhborg M, Matthiesen AS, Ransjö-Arvidson AB, Mukhamedrakhimov R, Uvnäs Moberg K, Widström AM (2009) Early contact versus separation: effects on mother–infant interaction one year later. Birth 36:97–109
Caldwell HK, Stephens SL, Young WS III (2008) Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice. Mol Psychiatry 14:190–196
Davis MC, Lee J, Horan WP, Clarke AD, McGee MR, Green MF, Marder SR (2013) Effects of single dose intranasal oxytocin on social cognition in schizophrenia. Schizophr Res 147(2–3):393–397
Ditzen B, Schaer M, Gabriel B, Bodenmann G, Ehlert U, Heinrichs M (2009) Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. Biol Psychiatry 65:728–731
Dodhia S, Hosanagar A, Fitzgerald DA, Labuschagne I, Wood AG, Nathan PJ, Phan KL (2014) Modulation of resting-state amygdala-frontal functional connectivity by oxytocin in generalized social anxiety disorder. Neuropsychopharmacology 39(9):2061–2069
Domes G, Kumbier E, Heinrichs M, Herpertz SC (2013) Oxytocin promotes facial emotion recognition and amygdala reactivity in adults with Asperger syndrome. Neuropsychopharmacology 39:698–706
Eckstein M, Hurlemann R (2013) Oxytocin: evidence for a therapeutic potential of the social neuromodulator. Nervenarzt 84(11):1321–1328
Eckstein M, Becker B, Scheele D, Scholz C, Preckel K, Schlaepfer TE, Hurlemann R (2014) Oxytocin facilitates the extinction of conditioned fear in humans. Biol Psychiatry
Gorka SM, Fitzgerald DA, Labuschagne I, Hosanagar A, Wood AG, Nathan PJ, Phan KL (2015) Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder. Neuropsychopharmacology 40(2):278–286
Grahn P, Tenngart Ivarsson C, Stigsdotter UK, Bengtsson I-L (2010) Using affordances as a health-promoting tool in a therapeutic garden. In: Ward Thompson C, Aspinall P, Bell S (Hrsg) Innovative approaches to researching landscape and health. Taylor & Francis, London
Grape C, Sandgren M, Hansson LO, Ericson M, Theorell T (2003) Does singing promote well-being?: an empirical study of professional and amateur singers during a singing lesson. Integr Physiol Behav Sci 38:65–74
Hegner P (2008) Leken som berör; sagor, lekar, sånger och ramsor till massage. Natur & Kultur, Stockholm
Heinrichs M, Gaab J (2007) Neuroendocrine mechanisms of stress and social interaction: implications for mental disorders. Curr Opin Psychiatry 20:158–162
Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria CM, Aronowitz BR, Mosovich S (2003) Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger’s disorders. Neuropsychopharmacology 28:193–198
Hollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E, Wasserman S (2007) Oxytocin increases retention of social cognition in autism. Biol Psychiatry 15:498–503
Huotari A, Herzig KH (2008) Vitamin D and living in northern latitudes—an endemic risk area for vitamin D deficiency. Int J Circumpolar Health 67:164–178
Insel TR (2003) Is social attachment an addictive disorder? Physiol Behav 79:351–357
Kanat M, Heinrichs M, Schwarzwald R, Domes G (2015) Oxytocin attenuates neural reactivity to masked threat cues from the eyes. Neuropsychopharmacology 40(2):287–295
Labuschagne I, Phan KL, Wood A, Angstadt M, Chua P, Heinrichs M, Nathan PJ (2010) Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder. Neuropsychopharmacology 35(12):2403–2413
Macdonald K, Feifel D (2013) Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders. Front Neurosci 7:35
Marazziti D, Catena Dell’Osso M (2008) The role of oxytocin in neuropsychiatric disorders. Curr Med Chem 15:698–704
Neumann ID, Landgraf R (2012) Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors. Trends Neurosci 35(11):649–659
Odent M (2007) When love hormones become useless. Midwifery Today Int Midwife 22:66
Ohlsson B, Truedsson M, Bengtsson M, Torstenson R, Sjölund K, Björnsson ES, Simrén M (2005) Effects of long-term treatment with oxytocin in chronic constipation; a double blind, placebo-controlled pilot trial. Neurogastroenterol Motil 17:697–704
Pedersen CA, Gibson CM, Rau SW, Salimi K, Smedley KL, Casey RL, Penn DL (2011) Intranasal oxytocin reduces psychotic symptoms and improves theory of mind and social perception in schizophrenia. Schizophr Res 132(1):50–53
Raina P, Waltner-Toews D, Bonnett B, Woodward C, Abernathy T (1999) Influence of companion animals on the physical and psychological health of older people: an analysis of a one-year longitudinal study. J Am Geriatr Soc 47:323–329
Robb SS, Stegman CE (1983) Companion animals and elderly people: a challenge for evaluators of social support. Gerontologist 23:277–282
Scantamburlo G, Hansenne M, Geenen V, Legros JJ, Ansseau M (2015) Additional intranasal oxytocin to escitalopram improves depressive symptoms in resistant depression: an open trial. Eur Psychiatry 30(1):65–68
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ (2014) Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther 149:150–190
Stoop R (2014) Neuromodulation by oxytocin and vasopressin in the central nervous system as a basis for their rapid behavioral effects. Curr Opin Neurobiol 29:187–193
Thompson MR, Callaghan PD, Hunt GE, Cornish JL, McGregor IS (2007) A role for oxytocin and 5-HT(1A) receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine („ecstasy“). Neuroscience 146:509–514
Uvnäs Moberg K, Petersson M (2004) Oxytocin–biochemical link for human relations. Mediator of antistress, well-being, social interaction, growth, healing. Läkartidningen 101:2634–2639
Uvnäs Moberg K, Petersson M (2005) Oxytocin, a mediator of anti-stress, well-being, social interaction, growth and healing. Z Psychosom Med Psychother 51:57–80
Uvnäs Moberg K, Petersson M (2009) Role of oxytocin and oxytocin related effects in manual therapies. In: King HH, Jänig W, Patterson PH (Hrsg) The science and clinical application of manual therapy. Elsevier, Edinburgh
Uvnäs Moberg K, Alster P, Svensson TH (1992) Amperozide and clozapine but not haloperidol or raclopride increase the secretion of oxytocin in rats. Psychopharmacology (Berl) 109:473–476
Uvnäs Moberg K, Björkstrand E, Hillegaart V, Ahlénius S (1999) Oxytocin as a possible mediator of SSRI-induced antidepressant effects. Psychopharmacology (Berl) 142:95–101
Zak PJ (2004) Neuroeconomics. Philos Trans R Soc B Biol Sci 359:1737–1748
Zak PJ (2008) The neurobiology of trust. Sci Am 298:88–92. Deutsche Ausgabe: (2009) Die Neurobiologie des Vertrauens. Spektrum der Wissenschaft April 2009:40–47
Zak PJ, Fakhar A (2006) Neuroactive hormones and interpersonal trust: international evidence. Econ Hum Biol 4:412–429
Zak PJ, Kurzban R, Matzner WT (2005) Oxytocin is associated with human trustworthiness. Horm Behav 48:522–527
Zak PJ, Stanton AA, Ahmadi S (2007) Oxytocin increases generosity in humans. PLoS One 2:e1128
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Moberg, K. (2016). Das Oxytocinerbe. In: Streit, U., Jansen, F. (eds) Oxytocin, das Hormon der Nähe. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47359-7_11
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