Abstract
High-nitrogen austenitic stainless steel (HNS) developed in NIMS shows high strength, high corrosion resistance, and nonmagnetic properties. This material was originally developed as a resource-saving type of HNS available in the seawater. It is well known that the nickel content of HNS can be reduced with increasing nitrogen content. In addition, it was found, derivatively, that nickel-free HNS was successfully produced with further increasing the nitrogen content, which is applicable to the field of biomedical area as an anti-nickel allergy biomaterial.
In this chapter, the following items are described such as production of HNS, mechanical properties, formability of HNS, corrosion properties, and the mechanism of the improvement of corrosion properties by addition of nitrogen. Finally, as one of the applications of HNS, R&D of coronary stent is introduced in terms of biocompatibility of HNS as well as in vivo test using the stents deployed into pigs’ coronary arteries. It is found that the stent made from nickel-free high-nitrogen stainless steel shows not only very excellent biocompatibility but also outstanding restenosis suppressant effect.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Holzgruber W (1988) Process technology for high-nitrogen steels. In: Proceedings of the international conference on high-nitrogen steels, HNS88, pp 39–48
Stein G, Hucklenbroich I, Feichtinger HK (1998) Current and future applications of high-nitrogen steels. In: Proceedings of the HNS-conference 1988, Espoo/Stockholm, Finland/Sweden, 151–160
Feichtinger H (1990) Alternative routes to the production of high-nitrogen steels. In: Proceedings of the 2nd international conference on high-nitrogen steels, HNS 90, pp 298–302
ISO 5832-9 (1992) Implants for surgery―metallic materials―Part 9: Wrought high-nitrogen stainless steel
Katada Y, Sagara M, Kobayashi Y, Kodama T (2004) Fabrication of high strength high-nitrogen stainless steel with excellent corrosion resistance and its mechanical properties. Mater Manuf Process 19(1):19–22
Katada Y, Washizu N, Baba H (2004) Localized corrosion behavior of Mn-free high-nitrogen steel. In: Proceedings of the HNS 2004, GRIPS Media, Ostend, Belgium, pp 549–554
Small WM, Pehlke RD (1968) The effect of alloying elements on the solubility of nitrogen in liquid iron-chromium-nickel alloys. Trans Metall Soc AIME 242:2501–2505
Stein G, Menzel J, Dorr H (1988) Industrial manufacture of massively nitrogen-alloyed steels. In: Proceedings of the international conference on high-nitrogen steels, HNS88, pp 32–38
Holzgruber W (1974) Austrian patent no. 333.327, S12
Feichtinger HK, Stein G (1999) Melting of high-nitrogen steels. Mater Sci Forum 318–320:261–270
Kubich CH, Holzgruber W (1971) Proceedings of the 3rd international symposium on electroslag and other special meeting technology, Pittsburgh
Lorenz K., Medawar G (1969) Thyssen Forschung 1:97–108
Okamoto H (1992) The effect of tungsten and molybdenum on the performance of super duplex stainless steels. In: Proceedings of application of stainless steel ’92, Stockholm, Sweden, Jernkontoret, p 360
Holmberg B (2002) Progress on welding of high nitrogen alloy austenitic stainless steels. Weld World 46(1–2):3–9
Jargelius-Petterson RFA (1998) Application of the pitting resistance equivalent to some highly alloyed stainless steels. Corrosion 54:162–168
Speidel Markus O, Zheng-Cui Ming-Ling, Kowanda Claudia, Speidel Hannes, Diener Markus (2003) High-nitrogen austenitic stainless steels – future materials for the chemical industries. Trans Indian Inst Met 56(3):281–286
Gebeau RC, Brown RS (2001) Biomedical implant alloy. Adv Mater Process 159(9):46–48
Hwang H-J, Park Y-S (2009) Effects of heat treatment on the phase ratio and corrosion resistance of duplex stainless steel. Mater Trans 50(6):1548–1552
Sagara M, Katada Y, Kodama T (2003) Localized corrosion behavior of high-nitrogen-bearing austenitic stainless steels in seawater environment. ISIJ Int 43(5):714–719
Osozawa K, Okato N (1976) Passivity and its breakdown on iron and steel based alloys (Stahle RW, Okada H, eds). NACE, Honolulu, p 135
Baba H, Katada Y (2008) Effect of nitrogen on crevice corrosion and repassivation behavior of austenitic stainless steel. Mater Trans 49(3):579–586
Baba H, Kodama T, Katada Y (2002) Role of nitrogen on the corrosion behavior of austenitic stainless steels. Corros Sci 44:2393–2407
Yashiro H, Hirayasu D, Kumagai N (2002) Effect of nitrogen alloying on the pitting of type 310 stainless steel. ISIJ Int 42(12):1477–1482
Lu YC, Bandy R, Clayton CR, Newman RC (1983) Surface enrichment of nitrogen during passivation of a highly resistant stainless-steel. J Electrochem Soc 130(8):1774–1776
Olsson C-OA (1995) The influence of nitrogen and molybdenum on passive films formed on the austenoferritic stainless steel-2205 studied by AES and XPS. Corros Sci 37:467–479
Komori T, Nakata M (1995) Effect of nitrogen on corrosion resistance of austenitic stainless steel. In: Proceedings of the 4th international congress on high-nitrogen steels, ISIJ, p 32
Baba H et al (2003) Proceedings of the 50th Japan conference on materials and environments, p 189
Newman RC, Shahrabi T (1987) The effect of alloyed nitrogen or dissolved nitrogen ions on the anodic behavior of austenitic stainless steel in hydrochloric-acid. Corros Sci 27(8):827–838
Huang CC, Tsai WT, Lee LT (1995) Electrochemical and surface studies on the passivity of nitrogen and molybdenum containing laser cladded alloys in 3.5 wt% NaCl solution. Corros Sci 37:769–780
Sagara M, Katada Y, Kodama T, Tsuru T (2003) Surface analysis of high nitrogen-bearing austenitic stainless steel using XPS. J Jpn Inst Metals 67:67–73
Katada Y, Sagara M, Kobayashi Y, Kodama T (2003) Fabrication of high strength high-nitrogen stainless steel with excellent corrosion resistance and its mechanical properties. In: Speidel MO (ed), Proceedings of HNS 2003, ETH Zurich, pp 189–198; Mudali UK (1994) Corrosion of high Nitrogen Steels – effects of nitrogen addition on passivation kinetics, composition of passivation films and pitting corrosion in Fe-N model alloys. Max-Planck Institute for Iron Research, Dusseldorf, Germany
Grabke HJ (1996) The role of nitrogen in the corrosion of iron and steels. ISIJ Int 36:777–786
Sagara M, Uno H, Katada Y, Kodama T (2002) Effect of alloy elements on localized corrosion characteristics of nitrogen-bearing stainless steels and evaluation of crevice corrosion in seawater environment. Tetsu-to-Hagane 88:86–91
Katada Y, Washizu N, Baba H (2005) Localized corrosion behavior of high-nitrogen steel. Mater Sci Forum 475–479:225–228; Wegrelius L, Falkenberg F, Olefjord I (1999) Passivation of stainless steels in hydrochloric acid. J Electrochem Soc 146:1397–1406
Dussaillant GR, Mintz GS, Pichard AD, Kent KM, Satler LF, Popma JJ, Wong SC, Leon MB (1995) Small stent size and intimal hyperplasia contribute to restenosis – a volumetric intravascular ultrasound analysis. J Am Coll Cardiol 26:720–724
Fischman DL, Leon MB, Baim DS, Schatz RA, Savavage MP, Penn I, Detre K, Veltri L, Ricci D, Nobuyoshi M, Cleman M, Heuser R, Almond D, Teirstein PS, Fish RD, Colombo A, Brinker J, Moses J, Shaknovich A, Hirshfeld J, Bailey S, Ellis S, Rake R, Goldberg S (1994) A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary-artery disease. New Engl J Med 331:496–501
Stone GW, Ellis SG, Cannon L, Mann JT, Greenberg JD, Spriggs D, O’Shaughnessy CD, DeMaio S, Hall P, Popma JJ, Koglin J, Russell ME (2005) Comparison of a polymer-based paclitaxel-eluting stent with a bare metal stent in patients with complex coronary artery disease – a randomized controlled trial. J Am Med Assoc 294:1215–1223
Peng T, Gibula P, Yao K, Goosen M (1996) Role of polymers in improving in improving the results of stenting in coronary arteries. Biomaterials 17:685–694
Mani G, Feldman MD, Patel D, Agrawal CM (2007) Coronary stents: a materials perspective. Biomaterials 28:1689–1710
Daemen J, Serruys PW (2007) Drug-Eluting Stent Update 2007 – Part I (2007) A survey of current and future generation drug-eluting stents: meaningful advances or more of the same? Circulation 116:316–328
Stone GW, Teirstein PS, Meredith IT, Farah B, Dubois CL, Feldman RL, Dens J, Hagiwara N, Allocco DJ, Dawkins KD (2011) A prospective, randomized evaluation of a novel everolimus-eluting coronary stent. J Am Coll Cardiol 57:1700–1708
McFadden EP, Stabile E, Regar E, Cheneau E, Ong ATL, Kinnaird T, Suddath WO, Weissman NJ, Torguson R, Kent KM, Pichard AD, Satler LF, Waksman R, Serruys PW (2004) Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy. Lancet 364:1519–1521
Costa M, Yan Y, Zhao DJ, Salnikov K (2003) Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling. J Environ Monit 5:222–223
Thomas P, Braathen LR, Doerig M, Auboeck J, Nestle F, Werfel T, Willert HG (2009) Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation. Allergy 64:1157–1165
Kuroda D, Hanawa T, Hibaru T, Kuroda S, Kobayashi M, Kobayashi T (2003) New manufacturing process of nickel-free austenitic stainless steel with nitrogen absorption treatment. Mater Trans 44:414–420
Katada Y, Sagara M, Kobayashi Y, Kodama T (2004) Fabrication of high strength high-nitrogen stainless steel with excellent corrosion resistance and its mechanical properties. Mater Manuf Process 19:19–30
Inoue M, Sasaki M, Katada Y, Taguchi T (2014) Quantitative biocompatibility evaluation of nickel-free high-nitrogen stainless steel in vitro/in vivo. J Biomed Mater Res B 102:68–72
Viemann D, Schmidt M, Tenbrock K, Schmid S, Muller V, Klimmek K, Ludwig S, Roth J, Goebeler M (2007) The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappa B and hypoxia-inducible factor-1 alpha. J Immunol 178:3198–3207
Fujiul K, Manabe I, Sasaki M, Inoue M, Iwata H, Hasumil E, Komuro I, Katada Y, Taguchi T, Nagai R (2012) Nickel-free stainless steel avoids neointima formation following coronary stent implantation. Sci Technol Adv Mater 13:10pp
Sasaki M, Inoue M, Katada Y, Taguchi T (2012) The effect of VEGF-immobilized nickel-free high-nitrogen stainless steel on viability and proliferation of vascular endothelial cells. Colloids Surf B: Biointerfaces 92:1–8
Inoue M, Sasaki M, Nakasu A, Takayanagi M, Taguchi T (2012) An antithrombogenic citric acid-crosslinked gelatin with endothelialization activity. Adv Healthc Mater 1:573–581
http://www.info.pmda.go.jp/ygo/pack/21800BZY10216000_A_01_04/
Acknowledgment
Some parts of this chapter, especially Sects. 6.2 and 6.4, were created by partially referencing the final report titled “Advances in Steel Research on the Availability of Nitrogen,” which was published by ISIJ as the final report of the research activities conducted by a research group of “the availability of nitrogen on the improvement in steel properties.”
One of the authors (Y. Katada), as the chairperson of the research group, would like to express his sincere gratitude to the coauthors of the report.
The authors would also like to express their deepest appreciation to Dr. Motoki Inoue and Dr. Makoto Sasaki for their enthusiastic contributions to the research associated with Sect. 6.5. This research was partly supported by the Japan Society for the Promotion of Science (JSPS) through its Funding Program for World-Leading Innovation R&D on Science and Technology (FIRST Program).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Katada, Y., Taguchi, T. (2015). Nickel-Free High-Nitrogen Stainless Steel. In: Niinomi, M., Narushima, T., Nakai, M. (eds) Advances in Metallic Biomaterials. Springer Series in Biomaterials Science and Engineering, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46836-4_6
Download citation
DOI: https://doi.org/10.1007/978-3-662-46836-4_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-46835-7
Online ISBN: 978-3-662-46836-4
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)