Strategy in Pediatric Patients



Appropriate care of the pediatric vascular anomaly patient is multidisciplinary and requires a correct understanding of the vascular tumors or malformations encountered, as well as an in-depth knowledge of the pediatric physiology. The vascular anomalies specialist must be aware of the unique issues inherent in providing medical care for neonates, infants, and children identifying the relationship between developmental stages and age-appropriate interventions in order to avoid potential complications. As an example, average blood volume ranges, in relation to age, from 100 ml/kg in premature babies to 70 ml/kg in adolescents, while normal heart rate is 160 bpm at 1 month of life and 80 bpm at puberty.


  1. 1.
    Karmazyn B, Ai H, Liang Y. Effect of body size on dose reduction with longitudinal tube current modulation in pediatric patients. Am J Roentgenol. 2015;204(4):861–4.CrossRefGoogle Scholar
  2. 2.
    Schüz J, Espina C. Villain P European Code against Cancer 4th edition: 12 ways to reduce your cancer risk. Cancer Epidemiol. 2015;9(15):127–37.Google Scholar
  3. 3.
    Cohen MD. Safe use of imaging contrast agents in children. J Am Coll Radiol. 2009;6(8):576–81.CrossRefPubMedGoogle Scholar
  4. 4.
    Aker J, Block RI, Biddle C. Anesthesia and the developing brain. AANA J. 2015;83(2):139–47.PubMedGoogle Scholar
  5. 5.
    Bailey KM, Bird SJ, McGrath PJ, Chorney JE. Preparing parents to be present for their child’s anesthesia induction: a randomized controlled trial. Anesth Analg. 2015;121:1001–10.CrossRefPubMedGoogle Scholar
  6. 6.
    Fortier MA, Kain ZN. Treating perioperative anxiety and pain in children: a tailored and innovative approach. Paediatr Anaesth. 2015;25(1):27–35.CrossRefPubMedGoogle Scholar
  7. 7.
    Léauté-Labrèze C, Hoeger P, Mazereeuw-Hautier J, et al. A randomized, controlled trial of oral propranolol in infantile hemangioma. N Engl J Med. 2015;372(8):735–46.CrossRefPubMedGoogle Scholar
  8. 8.
    Hoeger PH, Colmenero I. Vascular tumours in infants. Part I: benign vascular tumours other than infantile haemangioma. Br J Dermatol. 2014;171(3):466–73.CrossRefPubMedGoogle Scholar
  9. 9.
    Croteau SE, Liang MG, Kozakewich HP, Alomari AI, Fishman SJ, Mulliken JB, Trenor CC 3rdrd. Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals. J Pediatr 2013;162(1):142–7.Google Scholar
  10. 10.
    Fernandez-Pineda I, Lopez-Gutierrez JC, Chocarro G. Long-term outcome of vincristine-aspirin-ticlopidine (VAT) therapy for vascular tumors associated with Kasabach-Merritt phenomenon. Pediatr Blood Cancer. 2013;60(9):1478–81.CrossRefPubMedGoogle Scholar
  11. 11.
    Uno T, Ito S, Nakazawa A. Successful treatment of kaposiform hemangioendothelioma with everolimus. Pediatr Blood Cancer. Pediatr Blood Cancer. 2015;62(3):536–8.CrossRefPubMedGoogle Scholar
  12. 12.
    Flucke U, Vogels RJ, de Saint Aubain Somerhausen N, et al. Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases. Diagn Pathol. 2014;9:131.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Lee BB, Baumgartner I, Berlien HP. Consensus document of the International Union of Angiology (IUA)-2013. Current concept on the management of arterio-venous management. Int Angiol. 2013;32(1):9–36.PubMedGoogle Scholar
  14. 14.
    Bagrodia N, Defnet AM, Kandel JJ. Management of lymphatic malformations in children. Curr Opin Pediatr. 2015;27(3):356–63.CrossRefPubMedGoogle Scholar
  15. 15.
    Dasgupta R, Patel M. Venous malformations. Semin Pediatr Surg. 2014;23(4):198–202.CrossRefPubMedGoogle Scholar
  16. 16.
    Kulungowski AM, Fishman SJ. Management of combined vascular malformations. Clin Plast Surg. 2011;38(1):107–20.CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Vascular Anomalies CenterLa Paz Children’s Hospital, University of MadridMadridSpain

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