Congenital Vascular Malformations: An Historical Account

  • J. Leonel Villavicencio


Mild as well as severe vascular anomalies have been described in ancient documents by authors such as Hippocrates [1], Ambrose Pare [2], Galen [3], and others.


  1. 1.
    Adams F. The genuine works of hippocrates. XL1. On superfoetation. New York: William Wood and Co; 1844. p. 94.Google Scholar
  2. 2.
    Pare A. The works of the famous Chirurgion Ambrose Parey, Book 25 Translated by Thomas Johnson. London: Thomas Cote and R Young; 1634. p. 979.Google Scholar
  3. 3.
    Ballantyne JW. Teratogenesis. An inquiry into the causes of Monstrosities. Edinburgh: Oliver and Boyd; 1897. p. 15.Google Scholar
  4. 4.
    Medusa. Wikipedia. The free encyclopedia. Google Scholar.
  5. 5.
    Assimakopoulos E, Athanasiadis A, Zafrakas M, Dragoumis K, Bontis J. Caudal regresion syndrome and sirenomelia in only one twin in two diabetic pregnancies. Clin Exp Obstet Gynecol. 2004;31(2):151–3.PubMedGoogle Scholar
  6. 6.
    Garrido-Allepuz C, Haro E, Gonzalez D, Martinez ML, et al. A clinical and experimental overview of sirenomelia: insight into the mechanisms of congenital limb malformations. Dis Model Mech. 2011;4:289–99.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Duhamel B. From the mermaid to anal imperforation: the syndrome of caudal regression. Arch Dis Child. 1961;36:152–5.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Kallen B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Martinez-Frias ML, Mastroiacovo P, Robert E. The Cyclops and the mermaid: an epidemiological study of two types of rare malformation. J Med Genet. 1992;29(1):30–5.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Villavicencio JL. Venous malformations: introduction; historical background. Phlebology. 2007;22(6):247.Google Scholar
  10. 10.
    Virchow R.. Angiome. In: Die krankhaften Geschwulste. Berlin August Hirschwald, vol. 3; 1863. p. 306–425.Google Scholar
  11. 11.
    Malan E. Vascular malformations (Angiodysplasias). Milan: Carlo Erba Foundation; 1974.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.The Norman M. Rich Department of SurgeryUniformed Services University of the Health Sciences, Walter Reed National Military Medical CenterBethesdaUSA

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