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Organprotektive Intensivtherapie bei hirntoten Organspendern

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NeuroIntensiv

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Zusammenfassung

Die Organtransplantation ist eine erfolgreiche, etablierte Therapie für Patienten mit terminalem Organversagen. Der Mangel an Spenderorganen, aber auch eine inadäquate Therapie der gestörten Homöostase nach Eintritt des Hirntodes verhindert eine oftmals lebensrettende, zeitnahe Behandlung von rund 11.000 Patienten auf der Warteliste. Im Jahr 2013 wurden 3035 Organe in Deutschland postmortal gespendet und transplantiert. Diese Anzahl könnte gesteigert werden, denn Fortschritte in der Organkonservierung, der Transplantationstechnik und der immunsuppressiven Therapie ermöglichten eine Ausweitung der Spenderkriterien und des -alters. Eine offizielle Altersbegrenzung zur Organspende existiert nicht, vielmehr entscheiden die aktuellen Organfunktionen beim Spender und die medizinische Dringlichkeit beim Empfänger über die Eignung eines Organs zur Transplantation. Die Einleitung der Hirntoddiagnostik bei Patienten mit erloschenen Hirnstammreflexen auf neurochirurgischen Intensivstationen, eine konsequente Fortführung der organprotektiven Intensivtherapie und eine gezielte, organbezogenen Diagnostik sind von zentraler Bedeutung für eine höhere Anzahl und Qualität potenziell transplantierbarer Organe.

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Author information

Authors and Affiliations

  1. Region Nord-Ost, Deutsche Stiftung Organtransplantation (DSO), Straße des 17. Juni 106-108, 10623, Berlin, Deutschland

    Detlef Bösebeck Dr. & Klaus Böhler Dr.

  2. Leiter Medizinisches System Klinik Hirslanden, Klinik Hirslanden, Witellikerstrasse 40, 8032, Zürich, Schweiz

    Dietmar Mauer PD Dr.

Authors
  1. Detlef Bösebeck Dr.
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  2. Klaus Böhler Dr.
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  3. Dietmar Mauer PD Dr.
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Corresponding author

Correspondence to Detlef Bösebeck Dr. .

Editor information

Editors and Affiliations

  1. Neurologische Klinik, Universitätklinikum Erlangen, Erlangen, Germany

    Stefan Schwab

  2. Neurologische Klinik und Geriatrie, Johannes Wesling Klinikum Minden, Minden, Germany

    Peter Schellinger

  3. Klinik für Anästhesiologie, Klinikum der Johannes-Gutenberg-Universität Mainz, Mainz, Germany

    Christian Werner

  4. Neurochirurgische Klinik, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany

    Andreas Unterberg

  5. Neurologische Klinik, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany

    Werner Hacke

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Bösebeck, D., Böhler, K., Mauer, D. (2015). Organprotektive Intensivtherapie bei hirntoten Organspendern. In: Schwab, S., Schellinger, P., Werner, C., Unterberg, A., Hacke, W. (eds) NeuroIntensiv. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46500-4_42

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  • DOI: https://doi.org/10.1007/978-3-662-46500-4_42

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