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Cell-Specific Aptamers for Molecular Imaging

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Aptamers Selected by Cell-SELEX for Theranostics

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Abstract

Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligands. Since their discovery, aptamers have been rapidly translated into bioanalytical practice. They have been approved as molecular imaging and therapeutics tools. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This chapter aims to provide a summary of aptamers’ advantages as targeting ligands and their applications in molecular imaging.

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Authors and Affiliations

  1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, and Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, 410082, Changsha, China

    Jing Zheng & Ronghua Yang

  2. Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, 400715, Chongqing, China

    Chunmei Li

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  1. Jing Zheng
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  2. Chunmei Li
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  3. Ronghua Yang
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Correspondence to Jing Zheng or Ronghua Yang .

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Editors and Affiliations

  1. Department of Chemistry, Hunan University, Molecular Science and Biomedicine Laboratory, State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical Engineering, Changsha, China & University of Florida, Gainesville, Florida, USA

    Weihong Tan

  2. Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

    Xiaohong Fang

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Zheng, J., Li, C., Yang, R. (2015). Cell-Specific Aptamers for Molecular Imaging. In: Tan, W., Fang, X. (eds) Aptamers Selected by Cell-SELEX for Theranostics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46226-3_11

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