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Targeted and Personalized Therapy for Nonmelanoma Skin Cancers

  • Chantal C. Bachmann
  • Günther F. L. HofbauerEmail author
Chapter

Abstract

AK lesions are caused by chronic ultraviolet radiation exposure, and the presence of two or more AK lesions along with photodamage should raise consideration of a diagnosis of field cancerization. Treatment of AK and field cancerization should be driven by consideration of relevant patient, disease, and treatment factors, and appropriate treatment decisions will differ from patient to patient.

Keywords

Chronic Lymphocytic Leukemia Basal Cell Carcinoma Actinic Keratosis Organ Transplant Recipient Invasive Squamous Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

5-FU

5-Fluorouracil

AK

Actinic keratosis

ALA

5-Aminolevulinic acid

AZA

Azathioprine

BCC

Basal cell carcinoma

CLL

Chronic lymphocytic leukemia

CNI

Calcineurin inhibitors such as cyclosporin A, tacrolimus

COX-2

Cyclooxygenase-2

CsA

Cyclosporin A

LSRs

Local skin reactions

MAL

Methyl aminolevulinate

MMF

Mycophenolate mofetil

NHL

Non-Hodgkin lymphoma

NMSC

Nonmelanoma skin cancer

OTR

Organ transplant recipients

PDT

Photodynamic therapy

RCT

Randomized controlled trial

REAKT

Swiss Registry of Actinic Keratosis Treatment

SA

Salicylic acid

SCC

Squamous cell carcinoma

UV

Ultraviolet

UVA

Ultraviolet-A

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Chantal C. Bachmann
    • 1
  • Günther F. L. Hofbauer
    • 1
    Email author
  1. 1.Department of DermatologyUniversitätsSpital ZürichZürichSwitzerland

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