Abstract
Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.
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References
Blalock, A., Taussig, H.B.: The Surgical Treatment of Malformations of the Heart in Which there is Pulmonary Stenosis or Pulmonary Atresia. JAMA 128, 189–202 (1945)
Rodríguez, E., Soler, R., Fernández, R., Raposo, I.: Postoperative Imaging in Cyanotic Congenital Heart Diseases: Part 1, Normal findings. Am. J. Roentgenol. 189, 1353–1360 (2007)
de Leval, M.R., McKay, R., Jones, M., Stark, J., Macartney, F.J.: Modified Blalock–Taussig shunt: Use of the Subclavian Artery Orifice as Flow Regulator in Prosthetic Systemic Pulmonary Artery Shunts. J. Thorac. Cardiovasc. Surg. 81, 112–119 (1981)
Garson, A., Bricker, J.T., Fisher, D.J., Neish, S.R.: The Science and Practice of Pediatric Cardiology, 2nd edn. Williams & Wilkins, Baltimore (1998)
Liu, J.L., Qian, Y., Itatani, K., Murakami, A., Shiurba, R., Miyaji, K., Miyakoshi, T., Umezu, M.: Image-Based Computational Hemodynamics of Distal Aortic Arch Recoarctation Following the Norwood Procedure. In: 4th International Congress on Image and Singal Processing, pp. 318–323. IEEE Press, New York (2011)
Sun, Q., Liu, J.L., Qian, Y., Zhang, H.B., Wang, Q., Sun, Y.J., Hong, H.F., Liu, J.F.: Computational Haemodynamic Analysis of Patient-specific Virtual Operations for Total Cavopulmonary Connection with Dual Superior Venae Cavae. European Journal of Cardio-Thoracic Surgery (2013), doi:10.1093/ejcts/ezt394
Liu, J.L., Qian, Y., Itatani, K., Miyakoshi, T., Murakami, A., Ono, M., Shiurba, R., Miyaji, K., Umezu, M.: An Approach of Computational Hemodynamics for Cardiovascular Flow Simulation. In: ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, pp. 1449–1456. American Society of Mechanical Engineers (2011)
Qian, Y., Liu, J.L., Itatani, K., Miyaji, K., Umezu, M.: Computational Hemodynamic Analysis in Congenital Heart Disease: Simulation of the Norwood Procedure. Ann. Biomed. Eng. 38, 2302–2313 (2010)
McDonald, D.A.: Blood Flow in Arteries. Edward Arnold Ltd. (1974)
Fung, Y.C.: Biomechanics. Springer-Verlag (1981)
Launder, B.E., Sharma, B.I.: Application of the Energy Dissipation Model of Turbulence to the Calculation of Flow near a Spinning Disc. Letters in Heat Mass Transfer 1, 131–138 (1974)
Marsden, A.L., Vignon-Clementel, I.E., Chan, F.P., Feinstein, J.A., Taylor, C.A.: Effects of Exercise and Respiration on Hemodynamic Efficiency in CFD Simulations of the Total Cavopulmonary Connection. Ann. Biomed. Eng. 35, 250–263 (2007)
Barnea, O., Santamore, W.P., Rossi, A., Salloum, E., Chien, S., Austin, E.H.: Estimation of Oxygen Delivery in Newborns with a Univentricular Circulation. Circulation 98, 1407–1413 (1998)
Adel, M.M., Seth, L.A., Seigo, I.: Hemodynamic shear stress and its role in atherosclerosis. JAMA 282(21), 2035–2042 (1999)
Gimbrone, M.A., Resnick, N., Nagel, T., Khachigian, L.M., Collins, T., Topper, J.N.: Hemodynamics, Endothelial Gene Expression, and Atherogenesis. Ann. N. Y. Acad. Sci. 811(1), 1–10 (1997)
Odim, J., Portzky, M.D., Zurakowski, G., Wernovsky, R.P., Burke, R.P., Mayer, J.E., Castaneda, A.R., Jonas, R.A.: Sternotomy Approach for the Modified Blalock-Taussig Shunt. Circulation 92, II256–II261 (1995)
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Liu, J. et al. (2014). Influence of Conduit Angles on Hemodynamics of Modified Blalock-Taussig Shunt: Computational Analysis of Patient-Specific Virtual Procedures. In: Ma, S., Jia, L., Li, X., Wang, L., Zhou, H., Sun, X. (eds) Life System Modeling and Simulation. ICSEE LSMS 2014 2014. Communications in Computer and Information Science, vol 461. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45283-7_7
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DOI: https://doi.org/10.1007/978-3-662-45283-7_7
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