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Peste des Petits Ruminants Virus pp 95–118Cite as

Peste des Petits Ruminants in Unusual Hosts: Epidemiology, Disease, and Impact on Eradication

Abstract

Peste des petits ruminants (PPR) is primarily a highly contagious morbillivirus infection of small domesticated ruminants. However, it can also infect and cause disease in buffaloes, camels, and a variety of wild ungulates. In camels, it can cause serious disease, although experimental infection often failed to reproduce the natural situation. Clinical disease in wildlife has been observed in various locations of the Arabian Peninsula and in Asia. In numerous cases, there is epidemiological evidence of a spillover of PPR virus from sheep or goats to unusual hosts. Whilst there is clear evidence that a number of wildlife species are susceptible to infection, the actual role of wildlife in the epidemiology of PPR virus remains largely undetermined. Although an enzootic occurrence of PPR in unusual hosts has not been observed up to now, the epidemiological role of these hosts including wildlife populations should not be underestimated and is therefore important in PPR control and final eradication for reaching to PPR zero level.

Keywords

  • Small Ruminant
  • Wild Ungulate
  • Wild Ruminant
  • Dromedary Camel
  • Bronchiolar Epithelial Cell

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  • Anonymus (2013) Rinderpest has now been eradicated. http://en.wikivet.net/Rinderpest. Accessed on 29th Jan 2013

  • Abraham G, Sintayehu A, Libeau G, Albina E, Roger F, Laekemariam Y, Abayneh D, Awoke KM (2005) Antibody seroprevalences against peste des petits ruminants (PPR) virus in camels, cattle, goats and sheep in Ethiopia. Prev Vet Med 70:51–57

    CAS  PubMed  CrossRef  Google Scholar 

  • Abubakar AB, El-Yuduga AD, Baba SS (2008) Seroprevalence of morbillivirus antibody and abattoir survey of one humped slaughtered camels (Camelus dromedarius) in Maiduguri municipal abattoir, Maiduguri, Nigeria. Asian J Scient Res 1:85–89

    CrossRef  Google Scholar 

  • Abubakar M, Rajput ZI, Arshed MJ, Sarwar G, Ali Q (2011) Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrus blythi) in Pakistan as confirmed by detection of antigen and antibody. Trop Anim Health Prod 43:745–747

    PubMed  CrossRef  Google Scholar 

  • Abu Elzein EME, Housawi FMT, Bashareek Y, Gameel AA, Al-Afaleq AI, Anderson E (2004) Severe PPR infection in gazelles kept under semi-free range conditions. J Vet Med B 51:68–71

    CrossRef  Google Scholar 

  • Albayrak H, Gür S (2010) A serologic investigation for Peste des petits ruminants infection in sheep, cattle and camels (Camelus dromedarius) in Aydın province, West Anatolia. Trop Anim Health Prod 42:151–153

    CAS  PubMed  CrossRef  Google Scholar 

  • Albina E, Kwiatek O, Minet C, Lancelot R, Servan de Almeida R, Libeau G (2013) Peste des petits ruminants, the next eradicated animal disease? Vet Microbiol 165:38–44

    Google Scholar 

  • Anderson EC (1995) Morbillivirus infections in wildlife (in relation to their population biology and disease control in domestic animals). Vet Microbiol 44:319–332

    CAS  PubMed  CrossRef  Google Scholar 

  • Anderson EC, Hassan A, Barrett T, Anderson J (1990) Observations on the pathogenicity for sheep and goats and the transmission of the strain of virus isolated during the rinderpest outbreak in Sri Lanka 1987. Vet Microbiol 21:309–318

    CAS  PubMed  CrossRef  Google Scholar 

  • Anderson J, McKay JA (1994) The detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes. Epidemiol Infect 112:225–231

    CAS  PubMed Central  PubMed  CrossRef  Google Scholar 

  • Balamurugan V, Sen A, Venkatesan G, Bhanot V, Yadav V, Bhanuprakash V, Sing RK (2012) Peste des petits ruminants virus detected in tissues from an Asiatic lion (Panthera leo persica) belongs to Asian lineage IV. J Vet Sci 13:203–206

    Google Scholar 

  • Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G (2010) Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gen Virol 91:2885–2897

    CAS  PubMed  CrossRef  Google Scholar 

  • Bao J, Wang Z, Li L, Wu X, Sang P, Wu G, Ding G, Suo L, Liu C, Wang J, Zhao W, Li J, Qi L (2011) Detection and genetic characterization of peste des petits ruminants virus in free-living bharals (Pseudois nayaur) in Tibet, China. Res Vet Sci 90:238–240

    CAS  PubMed  CrossRef  Google Scholar 

  • Bao J, Wang Q, Parida S, Liu C, Zhang L, Zhao W, Wang Z (2012) Complete genome sequence of a Peste des Petits Ruminants Virus recovered from wild Bharal in Tibet, China. J Virol 86:10885–10886

    CAS  PubMed Central  PubMed  CrossRef  Google Scholar 

  • Baron MD, Parida S, Oura CA (2011) Peste des petits ruminants: a suitable candidate for eradication? Vet Rec 169:16–21

    Google Scholar 

  • Barrett T (1994) Rinderpest and distemper virus. In: Webster RG, Granoff A (eds) Encyclopedia of Virology, vol 3. Academic Press, San Diago, pp 1260–1268

    Google Scholar 

  • Couacy-Hymann E, Bidjeh K, Angba A, Domenech J, Diallo A (1995) Protection of goats against rinderpest by vaccination with attenuated peste des petits ruminants virus. Res Vet Sci 59:106–109

    CAS  PubMed  CrossRef  Google Scholar 

  • Couacy-Hymann E, Bodjo C, Danho T, Libeau G, Diallo A (2005) Surveillance of wildlife as a tool for monitoring rinderpest and peste des petits ruminants in West Africa. Rev Sci Tech 24:869–877

    CAS  PubMed  Google Scholar 

  • Dardiri AH, DeBoer CJ, Hamdy AH (1976) Response of American goats and cattle to peste des petits ruminants virus. In: Proceedings, 19th annual meeting, American Association of Veterinary Diagnosticians, pp 337–344

    Google Scholar 

  • Dhar P, Sreenivasa BP, Barrett T, Corteyn M, Singh RP, Bandyopadhyay SK (2002) Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol 88:153–159

    PubMed  CrossRef  Google Scholar 

  • Diallo A, Barrett T, Barbron M, Meyer G, Lefevre PC (1994) Cloning of the nucleocapsid protein gene of peste des petits ruminants virus: relationship to other morbilliviruses. J Gen Virol 75:233–237

    CAS  PubMed  CrossRef  Google Scholar 

  • Diallo A, Taylor WP, Lefevre PC, Provost A (1989) Attenuation d’une souche de la virus de peste des petits ruminants: candidat pour un vaccin homologue vivant. Rev Elev Med Vet Pays Trop 42:311–319

    CAS  PubMed  Google Scholar 

  • de Swart RL, Harder TC, Ross PS, Vos HW, Osterhaus AD (1995) Morbilliviruses and morbillivirus diseases of marine mammals. Infect Agents Dis 4:125–130

    PubMed  Google Scholar 

  • El-Hakim OA (2006) An outbreak of peste de petit ruminants (PPR) at Aswan province, Eygpt—Evaluation of some novel tools for diagnosis of PPR. Assiut Vet Med J 52:132–145

    Google Scholar 

  • Forsyth M, Barrett T (1995) Detection and differentiation of rinderpest and peste des petits ruminants viruses in diagnostic and experimental samples by polymerase chain reaction using P and F gene-specific primers. Virus Res 39:151–163

    CAS  PubMed  CrossRef  Google Scholar 

  • Furley CW, Taylor WP, Obi TU (1987) An outbreak of peste des petits ruminants in a zoological collection. Vet Rec 121:443–447

    CAS  PubMed  CrossRef  Google Scholar 

  • Gibbs EPJ, Taylor WP, Lawman MJP, Bryant J (1979) Classification of peste des petits ruminants as the fourth member of the genus morbillivirus. Intervirology 11:268–274

    CAS  PubMed  CrossRef  Google Scholar 

  • Govindarajan R, Koteeswaran A, Venugopalan AT, Shyam G, Shaquna S, Shaila MS, Ramachandranm S (1997) Isolation of pestes des petits ruminants virus from an outbreak in Indian buffalo (Bubalus bubalis). Vet Rec 141:573–574

    CAS  PubMed  CrossRef  Google Scholar 

  • Gür S, Albayrak H (2010) Seroprevalance of peste des petits ruminants (PPR) in goitered gazelle (Gazella subgutturosa subgutturosa) in Turkey. J Wildl Dis 46:673–677

    PubMed  CrossRef  Google Scholar 

  • Haas L, Baron MD, Liess B, Barrett T (1995) Editing of morbillivirus P gene transcripts in infected animals. Vet Microbiol 44:299–306

    CAS  PubMed  CrossRef  Google Scholar 

  • Hafez SM, Al-Sukayran A, Dela-Cruz D, Bekairi SI, Radwan AI (1987) Serological evidence for the occurrence of peste des petits ruminants among deer and gazelles in Saudi Arabia. In: Abu-Zinada AH, Goriup PD, Nader IA (eds) Proceedings of the first symposium for wildlife conservation and development in Saudi Arabia. National Commission for wildlife conservation and development. Publication 3

    Google Scholar 

  • Haffar A, Libeau G, Moussa A, Cecile M, Diallo A (1999) The matrix protein gene sequence analysis reveals close relationship between peste des petits ruminants virus (PPRV) and dolphin morbillivirus. Virus Res 64:69–75

    CAS  PubMed  CrossRef  Google Scholar 

  • Hamdy FM, Dardiri AH (1976) Response of white-tailed deer to infection with peste des petits ruminants virus. J Wildl Dis 12:516–522

    CAS  PubMed  CrossRef  Google Scholar 

  • Haroun M, Hajer I, Mukhtar M, Ali BE (2002) Detection of antibodies against peste des petits ruminants virus in sera of cattle, camels, sheep and goats in Sudan. Vet Res Commun 26:537–541

    CAS  PubMed  CrossRef  Google Scholar 

  • Hoffmann B, Wiesner H, Maltzan J, Mustefa R, Eschbaumer M, Arif FA, Beer M (2011) Fatalities in wild goats in Kurdistan associated with peste des petits ruminants virus. Transbound Emerg Dis 59:173–176

    PubMed  CrossRef  Google Scholar 

  • Ismail TM, Hassan HB, Nawal MA, Rakha GM (1992) Abd El-Halim MM, Fatebia MM. Studies on prevalence of rinderpest and peste des petits ruminants antibodies in camel sera in Egypt Vet Med J Giza 10:49–53

    Google Scholar 

  • Khalafalla AI, Saeed IK, Ali YH, Abdurrahman MB, Kwiatek O, Libeau G, Obeida AA, Abbas Z (2010) An outbreak of peste des petits ruminants (PPR) in camels in the Sudan. Acta Trop 116:161–165

    PubMed  CrossRef  Google Scholar 

  • Kinne J, Kreutzer R, Kreutzer M, Wernery U, Wohlsein P (2010) Peste des petits ruminants in Arabian wildlife. Epidemiol Infect 138:1211–1214

    CAS  PubMed  CrossRef  Google Scholar 

  • Komolafe OO, Ugwu HO, Ebirim RS (1987) An investigation into the possible role of peridomestic rats in the epizootiology of peste des petits ruminants in goats. Bull Anim Health Prod 35:207–210

    Google Scholar 

  • Kwiatek O, Ali YH, Saeed IK, Khalafalla AI, Mohamed OI, Obeida AA, Abdelrahman MB, Osman HM, Taha KM, Abbas Z, El Harrak M, Lhor Y, Diallo A, Lancelot R, Albina E, Libeau G (2011) Asian lineage of peste des petits ruminants virus, Africa. Emerg Infect Dis 17:1223–1231

    CAS  PubMed Central  PubMed  CrossRef  Google Scholar 

  • Kwiatek O, Minet C, Grillet C, Hurad C, Carlsson E, Karimov B, Albina E, Diallo A, Libeau G (2007) Peste des petits ruminants (PPR) outbreak in Tajikistan. J Comp Pathol 136:111–119

    CAS  PubMed  CrossRef  Google Scholar 

  • Libeau G, Lefevre PC (1990) Comparison of rinderpest and peste des petits ruminants viruses using anti-nucleoprotein monoclonal antibodies. Vet Microbiol 25:1–15

    CAS  PubMed  CrossRef  Google Scholar 

  • Libeau G, Prehaud C, Lancelot R, Colas F, Guerre L, Bishop DH, Diallo A (1995) Development of a competitive ELISA for detecting antibodies to the peste des petits ruminants virus using a recombinant nucleoprotein. Res Vet Sci 58:50–55

    CAS  PubMed  CrossRef  Google Scholar 

  • Libeau G, Diallo A, Colas F, Guerre L (1994) Rapid differential diagnosis of rinderpest and peste des petits ruminants using an immunocapture ELISA. Vet Rec 134:300–304

    CAS  PubMed  CrossRef  Google Scholar 

  • Mornet P, Orue J, Gilbert Y, Thiery G, Sow M (1956) La peste des petits ruminants en Afrique occidentale française et ses rapports avec la peste bovine. Rev Élev Méd Vét Pays trop 91:313–342

    Google Scholar 

  • Munir M (2014) Role of wild small ruminants in the epidemiology of peste des petits ruminants. Transbound Emerg Dis 61:411–424

    CAS  PubMed  CrossRef  Google Scholar 

  • Munir M, Zohari S, Berg M (2013) Molecular biology and pathogenesis of Peste des Petits Ruminants virus. Springer, New York, pp 69–104

    CrossRef  Google Scholar 

  • Nanda YP, Chatterjee A, Purohit AK, Diallo A, Innui K, Sharma RN, Libeau G, Thevasagayam JA, Brüning A, Kitching RP, Anderson J, Barrett T, Taylor WP (1996) The isolation of peste des petits ruminants virus from northern India. Vet Microbiol 51:207–216

    CAS  PubMed  CrossRef  Google Scholar 

  • Nawathe DR, Taylor WP (1979) Experimental infection of domestic pigs with the virus of peste des petits ruminants. Trop Anim Hlth Prod 11:120–122

    CAS  CrossRef  Google Scholar 

  • Norrby E, Utter G, Orvell C, Appel MJG (1986) Protection against canine distemper virus in dogs after immunization with isolated fusion protein. J Virol 58:536–541

    CAS  PubMed Central  PubMed  Google Scholar 

  • Ogunsanmi AO, Awe EO, Obi TU, Taiwo VO (2003) Peste des petits ruminants (PPR) virus antibodies in African grey Duiker (Sylvicapra Grimmia). Afr J Biomed Res 6:59–61

    Google Scholar 

  • Office International des Epizooties (2009) Peste des petits ruminants. Aetiology, epidemiology, diagnosis, prevention, and control references. OIE Technical disease card

    Google Scholar 

  • Office International des Epizooties (2012) OIE pilot project “Vaccine Standards and Pilot Approach to peste des petits ruminants (PPR) Control in Africa” receives funding from the Bill & Melinda Gates Foundation. (http://www.oie.int/for-the-media/press-releases/detail/article/oie-launches-pilot-project-to-design-efficient-control-methods-for-peste-des-petits-ruminants-a-dev/)

  • Özkul A, Akca Y, Alkan F, Barrett T, Karaoglu T, Dagalp SB, Anderson J, Yesilbag K, Cokcaliskan C, Gencay A, Burgu I (2002) Prevalence, distribution, and host range of peste des petits ruminants virus, Turkey. Emerg Inf Dis 8:708–712

    CrossRef  Google Scholar 

  • Roger F, Guebre Yesus M, Libeau G, Diallo A, Yigezu LM, Yilma T (2001) Detection of antibodies of rinderpest and peste des petits ruminants viruses (Paramyxoviridae, Morbillivirus) during a new epizootic disease in Ethiopian camels (Camelus dromedarius). Rev Méd Vét 152:265–268

    Google Scholar 

  • Roger F, Yigezu M, Hurard C, Libeau G, Mebratu GY, Diallo A, Faye B (2000) Investigations on a new pathological condition of camels in Ethiopia. J Camel Pract Res 7:163–165

    Google Scholar 

  • Rossiter P (2001) Peste des petits ruminants. In: Williams ES, Barker IK (eds) Infectious diseases of wild mammals, 3rd edn. Manson Publishing, London, pp 45–50

    Google Scholar 

  • Rossiter PB (2004) Peste des petits ruminants. In: Coetzer JAW (ed) Infectious diseases of livestock. 2nd ed, Oxford University Press, pp 660–672

    Google Scholar 

  • Roth L, King JM (1982) Nonlesions and lesions of no significance. Comp Cont Ed 4:S451–S456

    Google Scholar 

  • Saeed IK, Ali YH, Khalafalla AI, Rahman-Mahasin EA (2010) Current situation of peste des petits ruminants (PPR) in the Sudan. Trop Anim Health Prod 42:89–93

    PubMed  CrossRef  Google Scholar 

  • Saravanan P, Singh RP, Balamurgan V, Dhar P, Sreenivasa BP, Muthuchelvan D, Sen A, Aleyay AG, Singh RK, Bandyopadhyay SK (2004) Development of a N gene-based PCR-ELISA for detection of peste-des-petits-ruminants virus in clinical samples. Acta Virol 48:249–255

    CAS  PubMed  Google Scholar 

  • Scheid A, Caliguiri LA, Compans RW, Choppin PW (1972) Isolation of paramyxovirus glycoproteins. Association of both haemagglutinating and neuraminidase activities with the larger SV5 glycoprotein. Virology 50:640–652

    CAS  PubMed  CrossRef  Google Scholar 

  • Scott GR (1981) Rinderpest. In: Davis JR, Karstad LH, Trainer DO (eds) Infectious diseases of wild mammals, 2nd edn. Iowa State University Press, Ames, pp 18–30

    Google Scholar 

  • Shaila MS, Shamaki D, Forsyth MA, Diallo A, Goatley L, Kitching RP, Barrett T (1996) Geographic distribution and epidemiology of peste des petits ruminants virus. Virus Res 43:149–153

    CAS  PubMed  CrossRef  Google Scholar 

  • Sharawi SS, Yousef MR, Al-Hofufy AN, Al-Blowi MH (2010) Isolation, serological and real time PCR diagnosis of peste des petits ruminants virus in naturally exposed Arabian gazelle in Saudi Arabia. Vet World 3:489–494

    Google Scholar 

  • Singh RP (2011) Control strategies for Peste des petits ruminants in small ruminants of India. Rev sci tech Off int Epiz 30:879–887

    CAS  Google Scholar 

  • Singh RP (2012) Strategic control of peste des petits ruminants. In: Garg SR (ed) Veterinary and livestock sector: a blueprint for capacity building, pp 327–345

    Google Scholar 

  • Singh RP, Sreenivasa BP, Dhar P, Bandyopadhyay SK (2004a) A sandwich ELISA for the diagnosis of peste des petits ruminants (PPR) infection in small ruminants using anti-nucleocapsid protein monoclonal antibody. Arch Virol 149:2155–2170

    CAS  PubMed  CrossRef  Google Scholar 

  • Singh RP, Sreenivasa BP, Dhar P, Shah LC, Babdyopadhyay SK (2004b) Development of monoclonal antibody based competitive ELISA for detection and titration of antibodies to peste des petits ruminants virus. Vet Microbiol 98:3–15

    CAS  PubMed  CrossRef  Google Scholar 

  • Singh RP, Saravanan P, Sreenivasa BP, Singh RK, Bandyopadhyay SK (2004c) Prevalence and distribution of peste des petits ruminants (PPR) virus infection in small ruminants of India. Rev sci tech Off int Epiz 23:807–819

    CAS  Google Scholar 

  • Sreenivasa BP, Dhar P, Singh RP, Bandyopadhyay SK (2000) Evaluation of an indigenously developed homologous live attenuated cell culture vaccine against peste des petits ruminants infection of small ruminants. In: Proceedings of the XX annual conference of Indian association of veterinary microbiologists, immunologists and specialists in infectious diseases and National symposium on trends in vaccinology for animal diseases (College of veterinary Science, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttaranchal, India) p 84

    Google Scholar 

  • Tober C, Seufert M, Schneider H, Billeter MA, Johnston IC, Niewiesk S, Ter Meulen V, Schneider-Schaulie S (1998) Expression of measles virus V protein is associated with pathogenicity and control of viral RNA synthesis. J Virol 72:8124–8132

    CAS  PubMed Central  PubMed  Google Scholar 

  • Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, Suo L, Xie Z, Zhao W, Zhang W, Yang N, Li J, Wang S, Wang J (2009) Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis 15:299–301

    PubMed Central  PubMed  CrossRef  Google Scholar 

  • Wernery U (2011) Peste des petits ruminants (PPR) in camelids with own investigation. J Camel Pract Res 18:219–223

    Google Scholar 

  • Wohlsein P, Saliki J (2006) Rinderpest and peste des petits ruminants—the diseases: clinical signs and pathology. In: Barrett T, Pastoret P-P, Taylor WP (eds) Rinderpest and Peste des Petits Ruminants—Virus Plagues of large and small ruminants. Elsevier, Amsterdam, pp 68–85

    CrossRef  Google Scholar 

  • Woo PCY, Laua SKP, Wong BHL, Fan RYY, Wong AYP, Zhang AJX, Wu Y, Choi GKY, Li KM, Hui J, Wang M, Zheng B-J, Chan KH, Yuen K-Y (2012) Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats. Proc Nat Acad Sci 109:5435–5440

    CAS  PubMed Central  PubMed  CrossRef  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, University of Veterinary Medicine Foundation, Bünteweg 17, 30559, Hannover, Germany

    P. Wohlsein

  2. Division of Biological Products, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122, Uttar Pradesh, India

    R.P. Singh

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  1. The Pirbright Institute, Pirbright, Surrey, United Kingdom

    Muhammad Munir

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Wohlsein, P., Singh, R. (2015). Peste des Petits Ruminants in Unusual Hosts: Epidemiology, Disease, and Impact on Eradication. In: Munir, M. (eds) Peste des Petits Ruminants Virus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45165-6_6

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