Pityriasis rosea (PR) is a common, acute, or subacute self-limited papulosquamous skin disease. Approximately 1–2 % of new dermatological patients are affected by PR. PR affects mainly children, adolescents, and young adults. PR usually remits within 3–6 weeks. Viral etiology of PR is probable. Asymptomatic and mild cases may be left untreated. If itch is important, topical corticosteroids are indicated. Phototherapy (UVB or UVA1) may be useful in the treatment. High-dose oral acyclovir, if introduced early in the course of PR, may reduce the disease duration.


Pityriasis rosea Treatment Clinical features Differential diagnosis 

Further Reading

  1. Alzolibani AA, Zedan K. Macrolides in chronic inflammatory skin disorders. Mediators Inflamm. 2012;2012:159354. doi: 10.1155/2012/159354.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Browning JC. An update on pityriasis rosea and other similar childhood exanthems. Curr Opin Pediatr. 2009;21:481–5.CrossRefGoogle Scholar
  3. Chuh AA, Dofitas BL, Comisel GG, Reveiz L, Sharma V, Garner SE, et al. Interventions for pityriasis rosea. Cochrane Database Syst Rev. 2007;(2):CD005068.Google Scholar
  4. Drago F, Rebora A. Treatments for pityriasis rosea. Skin Therapy Lett. 2009;14:6–7.PubMedGoogle Scholar
  5. Drago F, Vecchio F, Rebora A. Use of high-dose acyclovir in pityriasis rosea. J Am Acad Dermatol. 2006;54:82–5.CrossRefGoogle Scholar
  6. Gambichler T, Terras S, Kreuter A. Treatment regimens, protocols, dosage, and indications for UVA1 phototherapy: facts and controversies. Clin Dermatol. 2013;31:438–54.CrossRefGoogle Scholar
  7. Rassai S, Feily A, Sina N, Abtahian S. Low dose of acyclovir may be an effective treatment against pityriasis rosea: a random investigator-blind clinical trial on 64 patients. J Eur Acad Dermatol Venereol. 2011;25:24–6.CrossRefGoogle Scholar
  8. Rebora A, Drago F, Broccolo F. Pityriasis rosea and herpesviruses: facts and controversies. Clin Dermatol. 2010;28:497–501.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Dermatovenereology, Faculty of MedicineUniversity of BelgradeBelgradeSerbia

Personalised recommendations