Lymphogranuloma venereum (LGV) has been renamed several times in the past and was known as tropical bubo, climatic bubo, poradenitis inguinalis, Durand-Nicolas-Favre disease, lymphopathia venereum and the fourth, fifth or sixth diseases. The causative agent of LGV is Chlamydia trachomatis genovar L. Worldwide, LGV is thought to account for 2–10 % of genito-ulcerative diseases in tropical climate areassuch as India and Africa. In Europe, North America and Australia, LGV is endemic mainly among HIV coinfected men who have sex with men. The first choice of treatment is an uninterrupted 21-day course of doxycycline 100 mg b.i.d.
Bis in die/two times a day
Men who have sex with men
Nucleic acid amplification test
Quater in die/four times a day
Sexually transmitted infection
- Banor Jr L, et al. Erythromycin treatment of lymphogranuloma venereum. In: Welch H et al., editors. Antibiotics annual 1953-54. New York: Medical Encyclopedia; 1953. p. 475–9.Google Scholar
- Centers for Disease Control and Prevention (CDC). Lymphogranuloma venereum among men who have sex with me--etherlands, 2003–2004. MMWR Morb Mortal Wkly Rep. 2004;53(42):985–8.Google Scholar
- Clinical Effectiveness Group of the British Association for Sexual Health and HIV (CEG/BASHH). 2006 National guideline for the management of lymphogranuloma venereum (LGV) of the British Association of Sexual Health and HIV (BASHH). 2006. http://www.bashh.org/documents/92/92.pdf.
- de Vries HJ, Reddy BS, Khandpur S. Chapter 41. Lymphogranuloma venereum. In: Gupta S, Kumar B, editors. Sexually transmitted infections. 2nd ed. New Delhi: Elsevier; 2012. p. 506–21.Google Scholar
- de Vries HJ, Zingoni A, White JA, Ross JD, Kreuter A. 2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens. Int J STD AIDS. 2013;18;25(7):465–474.Google Scholar
- Guidelines for the management of sexually transmitted infections, WHO 2003. Downloadable from: http://apps.who.int/iris/bitstream/10665/42782/1/9241546263_eng.pdf. Accessed 26 June 2013.
- Rodríguez-Domínguez M, Puerta T, Menéndez B, González-Alba JM, Rodríguez C, Hellín T, Vera M, González-Sainz FJ, Clavo P, Villa M, Cantón R, Del Romero J, Galán JC. Clinical and epidemiological characterization of a lymphogranuloma venereum outbreak in Madrid, Spain: co-circulation of two variants. Clin Microbiol Infect. 2014;20(3):219–25.CrossRefGoogle Scholar
- Davis TW, Goldstone SE. Sexually transmitted infections as a cause of proctitis in men who have sex with men. Dis Colon Rectum. 2009;52:507–12.Google Scholar
- de Vries HJ. Sexually transmitted infections in men who have sex with men. Clin Dermatol. 2014;32(2):181–8.Google Scholar
- de Vries HJ, Zingoni A, Kreuter A, Moi H, White JA. 2013 European guideline on the management of lymphogranuloma venereum. J Eur Acad Dermatol Venereol. 2014 doi: 10.1111/jdv.12461. [Epub ahead of print].
- de Vrieze NH, de Vries HJ. Lymphogranuloma venereum among men who have sex with men. An epidemiological and clinical review. Expert Rev Anti Infect Ther. 2014 Jun;12(6):697–704.Google Scholar
- Luk NM. Lymphogranuloma venereum. In: Kuen-kong LO, et al., editors. Social hygiene handbook, handbook of dermatology and venereology. Lisbon Social Hygiene Service, Department of Health; 1996. p. 1–14.Google Scholar
- van der Ham R, de Vries HJ. Lymphogranuloma venereum, where do we stand? Clinical recommendations. Drugs Today (Barc). 2009;45 Suppl B:39–43.Google Scholar
- Wright LT, et al. The treatment of lymphogranuloma venereum with terramycin. Antibiot Chemother. 1951;1:193–7.Google Scholar