Abstract
Lichen simplex chronicus (LSC) is an acquired severely itching chronic dermatosis. It consists of circumscribed lesions, evolving on sites prone to mechanical trauma such as rubbing and scratching. Patients should be well informed on the basic itch-scratch mechanisms and their relationship to the disease course, because the iatrogenic activity plays major role in the induction and perpetuation of the condition. General pruritus-relieving measures are simple and helpful approaches for long-term application. The therapeutic objectives focus on anti-inflammatory, antiseptic and antipruritic benefits. Highly individualised regimens are important to assure best treatment effect.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Further Reading
Drake L, Millikan L. The antipruritic effect 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group. Arch Dermatol. 1995;131:1403–8.
Kantor G, Resnik K. Treatment of LSC with topical capsaicin cream. Acta Derm Venereal. 1996;76:161.
Katsambas A. In: Milikan L, editor. Antihistamines. Drug therapy in dermatology. New York: Marcel Dekker; 2000. p. 243–51.
Lotti T, Hautmann G, Panconesi I. Neuropeptides. Skin. 1995;33:482–96.
Peters M, Loewenberg H. Prognose und Behandlungserfold bei stationaerer psychotherapentisch-dermatologischer Behandlung von Neurodermitis patienten. Hautarzt. 1993;44:210–4.
Voalasti A, Suomalainen H. Calcitonin gene-related peptide immunoreactivity in prurigo nodularis: a comparative study with neurodermatitis circumscripta. Br J Dermatol. 1989;120:619–23.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Gantcheva, M., Broshtilova, V. (2015). Lichen Simplex Chronicus. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D’Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45139-7_54
Download citation
DOI: https://doi.org/10.1007/978-3-662-45139-7_54
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-45138-0
Online ISBN: 978-3-662-45139-7
eBook Packages: MedicineMedicine (R0)