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Bowen’s Disease

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Book cover European Handbook of Dermatological Treatments

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Abstract

Bowen’s disease (BD) is an intraepidermal squamous cell carcinoma (SCC) with a tendency for progressive growth and low invasive risk, characterized by slowly growing, erythematous plaque with an irregular border, surface scaling and crusting. The risk of progression to invasive SCC is 3–5 % for extragenital lesions and 10 % for genital lesions. BD is very common in the Caucasian population with an incidence of 14 per 100,000 in some populations. The peak age group for BD is the seventh decade. The ratio of Bowen’s disease is approximately equal between males and females. BD is more commonly found on the head and neck of men and on the lower limbs and cheeks of women. BD is usually a solitary lesion, but in 10–20 % of patients, it occurs at multiple sites.

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Abbreviations

5-FU:

5-Fluorouracil

ALA:

5-Aminolevulinic acid

BD:

Bowen’s disease

HPV:

Human papillomavirus

MAL:

Methyl aminolevulinate

PDT:

Photodynamic therapy

SCC:

Squamous cell carcinoma

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Authors and Affiliations

  1. Department of Dermatovenerology, Dermatooncology Unit, University Hospital Centre “Sestre Milosrdnice”, Zagreb, Croatia

    Mirna Situm

  2. Referral Centre for Melanoma of the Ministry of Health of the Republic of Croatia, Zagreb, Croatia

    Mirna Situm

  3. School of Dental Medicine, University of Zagreb, Zagreb, Croatia

    Mirna Situm

  4. President of the Croatian Dermatovenereological Society of the Croatian Medical Association, Zagreb, Croatia

    Mirna Situm

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  1. Mirna Situm
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Correspondence to Mirna Situm .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Andreas Syggros Hospital University of Athens, Athens, Greece

    Andreas D. Katsambas  & Clio Dessinioti  & 

  2. University of Rome “G. Marconi”, Rome, Italy

    Torello M. Lotti

  3. Centro Studi per la Ricerca Multidisciplinare Rigenerativa (CSRMR), Rome, Italy

    Torello M. Lotti

  4. Unit of Dermatology, University of Pisa, Pisa, Italy

    Angelo Massimiliano D’Erme

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Situm, M. (2015). Bowen’s Disease. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D’Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45139-7_10

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  • DOI: https://doi.org/10.1007/978-3-662-45139-7_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45138-0

  • Online ISBN: 978-3-662-45139-7

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