Zusammenfassung
Ablagerungsdermatosen sind eine heterogene Gruppe von Erkrankungen, deren Gemeinsamkeit darin besteht, dass es zu einer Ansammlung endogener oder exogener Substanzen in der Dermis und/oder Subkutis kommt. Aufgrund der Heterogenität der abgelagerten Substanzen ist eine einheitliche Klassifikation der Ablagerungsdermatosen schwierig. Bewährt haben sich die Unterscheidungen nach endogen und exogen bedingten Ablagerungen. Endogene Substanzen können entweder direkt oder als Folge einer Stoffwechselstörung in der Haut abgelagert werden. Exogen induzierte Ablagerungsdermatosen werden unterschieden nach Ablagerungen durch systemische oder durch topische Applikationen. Eine andere gebräuchliche Klassifikation orientiert sich an der Art der abgelagerten Substanzen. Die histopathologischen Veränderungen von Ablagerungen in der Haut sind häufig sehr diskret, jedoch bei Kenntnis ihrer in der Regel typischen Muster gut zu identifizieren.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Weiterführende Literatur
Weiterführende Literatur zu Amyloidosen
Breathnachc SM (1988) Amyloid and amyloidosis. J Am Acad Dermatol 18:1–16
Chapel TA, Birmingham DJ, Malinowski YE (1977) Nodular primary localized cutaneous amyloidosis. Arch Dermatol 113:1248–1249
Hashimoto K, Ito K, Kumakiri M, Headington J (1987) Nylon brush macular amyloidosis. Arch Dermatol 123:633–637
Ratz JL, Bailin PL (1981) Cutaneous amyloidosis. J Am Acad Dermatol 4:21–26
Röcken C, Ernst J, Hund E, Michels H, Perz J, Saeger W, Sezer O, Spuler S, Willig F, Schmidt HHJ (2006) Interdisziplinäre Leitlinien zur Diagnostik und Therapie der extrazerebralen Amyloidosen. Dtsch Med Wochenschr 131:S 45–S 66
Touart DM, Sau P (1998a) Cutaneous deposition diseases. Part I. J Am Acad Dermatol 39:149–171
Weyers W, Weyers I, Bonczkowitz M, Diaz-Cascajo C, Schill WB (1997) Lichen amyloidosus: a consequence of scratching. J Am Acad Dermatol 37:923–928
Weiterführende Literatur zu Kolloidmilium
Handfield-Jones SE, Atherton DJ, Black MM, Hashimoto K, Mc Kee PH (1992) Juvenile colloid milium: clinical, histological and ultrastructural features. J Cutan Pathol 19:434–438
Hashimoto K, Black MM (1985) Colloid milium: a final degeneration product of actinic elastoid. J Cutan Pathol 12:147–156
Mayer FE, Milburn PP (1990) Unilateral colloid milium. J Am Acad Dermatol 23:1166–1167
Weiterführende Literatur zu Hyalinosis cutis et mucosae
Chaudhary SJ, Dayal PK (1995) Hyalinosis cutis et mucosae: review with a case report. Oral Surg Oral Med Oral Pathol 80:168–171
Hamada T, McLean WH, Ramsay M, Ashton GH, Nanda A, Jenkins T, Edelstein I, South AP, Bleck O, Wessagowit V, Mallipeddi R, Orchard GE, Wan H, Dopping-Hepenstal PJ, Mellerio JE, Whittock NV, Munro CS, van Steensel MA, Steijlen PM, Ni J, Zhang L, Hashimoto T, Eady RA, McGrath JA (2002) Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1). Hum Mol Genet 11:833–840
Metze D (1999) Explaining clinical features and histopathological findings by electron microscopy: Hyalinosis cutis et mucosae (Urbach-Wiethe). Dermatopathol: Pract Conceptual 5:46–47
Stavrianeas N, Karpouzis A, Vamvassakis E, Patrou A, Koumantaki-Mathioudaki E, Papadopoulos O (1997) Hyalinose cutanéomuqueuse: trois cas. Ann Dermatol Venerol 124:171–175
Weiterführende Literatur zu erythropoetische Protoporphyrie
Bishop DF, Tchaikovskii V, Nazarenko I, Desnick RJ (2013) Molecular expression and characterization of erythroid-specific 5-aminolevulinate synthase gain-of-function mutations causing X-linked protoporphyria. Mol Med 19:18–25
Hanneken S, Kürten V, Reifenberger J, Ruzicka T, Neumann NJ (2006) Erythropoetische Protoporphyrie im Kindesalter. Hautarzt 57:318–319
Weiterführende Literatur zu juvenile hyaline Fibromatose
Antaya RJ, Cajaiba MM, Madri J, Lopez MA, Ramirez MC, Martignette JA, Reyey-Mugica M (2007) Juvenile hyaline fibromatosis and infantile systemic hyalinosis overlap associated with a novel mutation in capillary morphogenesis protein-2 gene. Am J Dermatopathol 29:99–103
Dowling O, Difeo A, Ramirez MC, Tukel T, Narla G, Bonafe L, Kayserili H, Yuksel-Apak M, Paller AS, Norton K, Teebi AS, Grum-Okars V, Martin GS, Davis GE, Glucksman MJ, Martignetti JA (2003) Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile sytemic hyalinosis. Am J Hum Genet 73:957–966
Güldner K, Hendricks C, Schaller J, Kunze J (2009) Juvenile hyaline fibromatose. Hautarzt 60:740–742
Weiterführende Literatur zu Muzinosen
Cowper SE, Robin HS, Steinberg SM, Su LD, Gupta S, LeBoit PE (2000) Scleromyxoedema-like cutaneous diseases in renal-dialysis patients. Lancet 356:1000–1001
Dineen AM, Dicken CH (1995) Scleromyxedema. J Am Acad Dermatol 20:157–160
Flowers SL, Cooper PH, Landes HB (1989) Acral persistent papular mucinosis. J Am Acad Dermatol 21:293–297
Heymann WR (1992) Cutaneous manifestions of thyroid disease. J Am Acad Dermatol 26:885–902
Rongioletti F, Rebora A (1991) The new cutaneous mucinoses: a review with an up-to date classification of cutaneous mucinoses. J Am Acad Dermatol 24:265–270
Ruiz H, Sanchez JL (1999) Tumid lupus erythematosus. Am J Dermatopathol 21:356–360
Somach SC, Helm TN, Lawker KB (1993) Pretibial mucin, histologic pattern and clinical correlation. Arch Dermatol 26:885–902
Steigleder GK, Küchmeister B (1985) Cutaneous mucinous deposits. J Cutan Pathol 12:334–347
Truhan AP, Roenigk HH (1986) The cutaneous mucinoses. J Am Acad Dermatol 14:1–18
Weiterführende Literatur zu Kalzinosen
Duh Q-Y, Lim RC, Clark OH (1991) Calciphylaxis in secondary hyperparathyroidism. Arch Surg 126:1213–1219
Khafif RA, Delima C, Silverberg A, Frankel R (1990) Calciphylaxis and systemic calcinosis: collective review. Arch Intern Med 150:956–959
Touart DM, Sau P (1998b) Cutaneous deposition diseases, Part II. J Am Acad Dermatol 34:527–544
Walsh JS, Failey JA (1995) Calcifying disorders of the skin. J Am Acad Dermatol 33:693–706
Weiterführende Literatur zur kutanen Ossifikation
Boehncke W–H, Kaufmann R, Weber L, Sterry W (1993) Osteoma cutis. Mult Miliäre Osteome Gesicht Hautarzt 44:245–247
Burgdorf W, Nasemann T (1977) Cutaneous osteomas: a clinical and histiopathologic review. Arch Dermatol Res 260:121–135
Molina-Ruiz A, Cerroni L, Kutzner H, Requena L (2014) Cutaneous deposits. Am J Dermatopathol 36:1–48
Weiterführende Literatur zur Gicht
LeBoit PE, Schneider S (1987) Gout presenting as lobular panniculitis. Am J Dermatopath 9:334–338
O´Duffy JD, Hunder CG, Kelley PJ (1975) Decreasing prevalence of tophaceous gout. Mayo Clin Proc 50:227–228
Wernick R, Winkler C, Campbell S (1992) Tophi as the initial manifestion of gout. Report of six cases and review of the literature. Arch Intern Med 152:873–876
Weiterführende Literatur zu Pigment-, Schwermetall-und Medikamentenablagerungen
Albers SE, Brozena SJ, Glass LF, Frenske NA (1982) Alkatonuria and ochronosis: case report and review. J Am Acad Dermatol 17:609–614
Dereure O (2001) Drug induced skin pigmentation. Epidemology, diagnosis and treatment. Am J Clin Dermatol 2:253–262
Goldstein AP (1979) Histologic reactions in tattoos. J Dermatol Surg Oncol 5:896–900
Granstein RD, Sober AJ (1981) Drug – and heavy metal-induced hyperpigmentation. J Am Acad Dermatol 5:1–18
Lawrence N, Bligard CA, Reed R, Perret WJ (1988) Exogenous ochronosis in the United States. J Am Acad Dermatol 18:1207–1211
Mahler R, Sissons W, Watters K (1986) Pigmentation induced by quinidine therapy. Arch Dermatol 122:1062–1064
Morton CA, Fallwfield M, Kemmett D (1996) Localized argyria caused by silver earrings. Brit J Dermatol 135:484–485
Smith RW, Leppard B, Barnett NL, Millward-Sadler GH, McCrae F, Cawley MI (1995) Chrysiasis revisited: a clinical and pathological study. Br J Dermatol 133:671–678
Sweeney SA, Hicks LD, Ranallo N, Snyder N, Soldano NC (2013) Perforating granulomatous dermatitis reaction to exogenous tattoo pigment: a case report and review of the literature. Am J Dermatopathol 35:754–756
Tidman MJ, Horton JJ, Mac Donald DM (1986) Hydrochinon-induced ochronosis-light and electron microscopic features. Clin Exp Dermatol 11:224–228
Weiterführende Literatur zu Hautimplantaten
Requena L, Requena C, Christiansen L, Zimmermann US, Kutzner H, Cerroni L (2011) Adverse reactions to injectable soft tissue fillers. J Am Acad Dermatol 64:1–34
Weiterführende Literatur zu Oxalose
Blackmon JA, Jeffy BG, Malone JC, Knable AL Jr (2011) Oxalosis involving the skin: case report and literature review. Arch Dermatol 147:1302–1305
Coral A, van Holsbeeck M, Hegg C (1990) Case report 599: secondary renal failure (oxalate gout). Skelet Radiol 19:147–149
Spiers EM, Sanders DY, Omura EF (1990) Clinical and histological features of primary oxalosis. J Am Acad Dermatol 22:952–956
Winship IM, Saxe NP, Hugel H (1991) Primary oxalosis – an unusual cause of livedo reticularis. Clin Exp Dermatol 16:367–370
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Schaller, J., Meigel, W.N. (2016). Ablagerungsdermatosen. In: Cerroni, L., Garbe, C., Metze, D., Kutzner, H., Kerl, H. (eds) Histopathologie der Haut. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45133-5_24
Download citation
DOI: https://doi.org/10.1007/978-3-662-45133-5_24
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-45132-8
Online ISBN: 978-3-662-45133-5
eBook Packages: Medicine (German Language)