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Colon Capsule Endoscopy in Inflammatory Bowel Disorders

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Abstract

Clinical symptoms of inflammatory bowel disorders (IBDs) comprise diarrhea and abdominal pain, and inflammatory markers are often elevated in serum and stool. Ulcerative colitis (UC) and Crohn’s disease (CD), the major types of chronic IBD, are characterized by episodes when symptoms flare up, followed by periods of improvement and clinical remission. The disease is lifelong and frequently manifests in the first decades of life. Detailed endoscopic visualization of the intestinal mucosa is required in these patients to diagnose or to exclude the disease. Thereby, complete investigation of the colon, the small bowel, and the upper gastrointestinal tract may be optimal to establish the exact diagnosis of IBD and to describe the distribution of the disease (Figs. 48.1 and 48.2). Colon capsule endoscopy (CCE) is convincing in combining endoscopy of the colon and of the small bowel. It could therefore become the ideal test to screen for intestinal inflammation (Figs. 48.3 and 48.4) and to monitor the effect of therapeutic measures in the small and the large bowel.

The work was first published in 2006 by Springer Medizin Verlag Heidelberg with the following title: Atlas of Video Capsule Endoscopy.

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References

  1. Albert JG, Martiny F, Krummenerl A, et al. Diagnosis of small bowel Crohn’s disease: a prospective comparison of capsule endoscopy with magnetic resonance imaging and fluoroscopic enteroclysis. Gut. 2005;54:1721–7.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Bourreille A, Ignjatovic A, Aabakken L, et al. Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED-ECCO consensus. Endoscopy. 2009;41:618–37.

    Article  CAS  PubMed  Google Scholar 

  3. Maunoury V, Savoye G, Bourreille A, et al. Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified). Inflamm Bowel Dis. 2007;13:152–5.

    Article  PubMed  Google Scholar 

  4. Lopes S, Figueiredo P, Portela F, et al. Capsule endoscopy in inflammatory bowel disease type unclassified and indeterminate colitis serologically negative. Inflamm Bowel Dis. 2010;16:1663–8.

    Article  PubMed  Google Scholar 

  5. Murrell Z, Vasiliauskas E, Melmed G, et al. Preoperative wireless capsule endoscopy does not predict outcome after ileal pouch-anal anastomosis. Dis Colon Rectum. 2010;53:293–300.

    Article  PubMed  Google Scholar 

  6. Triester SL, Leighton JA, Leontiadis GI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn’s disease. Am J Gastroenterol. 2006;101:954–64.

    Article  PubMed  Google Scholar 

  7. van Tuyl SAC, van Noorden JT, Stolk MFJ, Kuipers EJ. Clinical consequences of videocapsule endoscopy in GI bleeding and Crohn’s disease. Gastrointest Endosc. 2007;66:1164–70.

    Article  PubMed  Google Scholar 

  8. Rutgeerts P, Geboes K, Vantrappen G, et al. Predictability of the postoperative course of Crohn’s disease. Gastroenterology. 1990;99:956–63.

    CAS  PubMed  Google Scholar 

  9. Rutgeerts P, Van Assche G, Vermeire S, et al. Ornidazole for prophylaxis of postoperative Crohn’s disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology. 2005;128:856–61.

    Article  CAS  PubMed  Google Scholar 

  10. Regueiro M, Schraut W, Baidoo L, et al. Infliximab prevents Crohn’s disease recurrence after ileal resection. Gastroenterology. 2009;136:441–50.

    Article  CAS  PubMed  Google Scholar 

  11. Baert F, Moortgat L, Van Assche G, et al. Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn’s disease. Gastroenterology. 2010;138:463–8.

    Article  PubMed  Google Scholar 

  12. Colombel JF, Rutgeerts P, Reinisch W, et al. Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology. 2011;141:1194–201.

    Article  CAS  PubMed  Google Scholar 

  13. Spada C, Hassan C, Galmiche JP, et al. Colon capsule endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2012;44:527–36.

    Article  CAS  PubMed  Google Scholar 

  14. Sung J, Ho KY, Chiu HM, et al. The use of Pillcam Colon in assessing mucosal inflammation in ulcerative colitis: a multicenter study. Endoscopy. 2012;44:754–8.

    Article  CAS  PubMed  Google Scholar 

  15. Ye CA, Gao YJ, Ge ZZ, et al. PillCam colon capsule endoscopy versus conventional colonoscopy for the detection of the severity and extent of ulcerative colitis. J Dig Dis. 2013;14:117–24.

    Article  CAS  PubMed  Google Scholar 

  16. Acosta MSJ, Cuesta AB, Álvarez ÁC, et al. Pillcam Colon (C2) vs colonoscopy in the assessment of colon mucosa in patients with ulcerative colitis. Endoscopy. 2012;44:A126.

    Google Scholar 

  17. Heinzow HS, Lügering A, Domagk D, et al. Assessing disease activity of ulcerative colitis with colon capsule endoscopy versus standard colonoscopy. Gut. 2012;61:A27.

    Google Scholar 

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Correspondence to Joseph J. Y. Sung .

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© 2014 Springer-Verlag Berlin Heidelberg

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Sung, J.J.Y., Albert, J.G. (2014). Colon Capsule Endoscopy in Inflammatory Bowel Disorders. In: Keuchel, M., Hagenmüller, F., Tajiri, H. (eds) Video Capsule Endoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44062-9_48

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  • DOI: https://doi.org/10.1007/978-3-662-44062-9_48

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44061-2

  • Online ISBN: 978-3-662-44062-9

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