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Biobanks – A Source of Large Biological Data Sets: Open Problems and Future Challenges

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Interactive Knowledge Discovery and Data Mining in Biomedical Informatics

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 8401))

Abstract

Biobanks are collections of biological samples (e.g. tissues, blood and derivatives, other body fluids, cells, DNA, etc.) and their associated data. Consequently, human biobanks represent collections of human samples and data and are of fundamental importance for scientific research as they are an excellent resource to access and measure biological constituents that can be used to monitor the status and trends of both health and disease. Most -omics data trust on a secure access to these collections of stored human samples to provide the basis for establishing the ranges and frequencies of expression. However, there are many open questions and future challenges associated with the large amounts of heterogeneous data, ranging from pre-processing, data integration and data fusion to knowledge discovery and data mining along with a strong focus on privacy, data protection, safety and security.

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Author information

Authors and Affiliations

  1. Biobank Graz, Medical University of Graz, Neue Stiftingtalstraße 2a, 8036, Graz, Austria

    Berthold Huppertz

  2. Institute for Medical Informatics, Statistics & Documentation, Research Unit HCI, Medical University of Graz, Auenbruggerplatz 2/V, 8036, Graz, Austria

    Andreas Holzinger

Authors
  1. Berthold Huppertz
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  2. Andreas Holzinger
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Editors and Affiliations

  1. Research Unit Human-Computer Interaction, Austrian IBM Watson Think Gruop, Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Auenbruggerplatz 2/V, 8036, Graz, Austria

    Andreas Holzinger

  2. IBM Life Sciences Discovery Centre, TECHNA for the Advancement of Technology for Health, Princess Margaret Cancer Centre, University Health Network, TMDT Room 11-314, 101 College Street, M5G 1L7, Toronto, ON, Canada

    Igor Jurisica

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Huppertz, B., Holzinger, A. (2014). Biobanks – A Source of Large Biological Data Sets: Open Problems and Future Challenges. In: Holzinger, A., Jurisica, I. (eds) Interactive Knowledge Discovery and Data Mining in Biomedical Informatics. Lecture Notes in Computer Science, vol 8401. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43968-5_18

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  • DOI: https://doi.org/10.1007/978-3-662-43968-5_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-43967-8

  • Online ISBN: 978-3-662-43968-5

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