Advertisement

Future Development of Infectious Microecology

  • Lanjuan Li
  • Yanfei Chen
Part of the Advanced Topics in Science and Technology in China book series (ATSTC)

Abstract

More and more studies indicate interactions between infectious diseases and microbiota. Advances in molecular techniques have led to a greater appreciation of the diversity of human microbiota, the extent of interactions with the human host, and how that relates to inter-individual variation. Realization of the interaction between infectious agents and the microbiota will definitely deepen our understanding of infectious diseases.

Keywords

Acute Myeloid Leukemia Irritable Bowel Syndrome Clostridium Difficile Infection Lactobacillus Reuteri Saccharomyces Boulardii 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    Konopka A. What is microbial community ecology? ISME J, 2009, 3: 1223–1230.CrossRefPubMedGoogle Scholar
  2. [2]
    Raes J, Bork P. Molecular eco-systems biology: towards an understanding of community function. Nat Rev Microbiol, 2008, 6: 693–699.CrossRefPubMedGoogle Scholar
  3. [3]
    Xu J, Mahowald M A, Ley R E, et al. Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol, 2007, 5: e156.Google Scholar
  4. [4]
    Gorbach S L, Barza M, Giuliano M, et al. Colonization resistance of the human intestinal microflora: Testing the hypothesis in normal volunteers. Eur J Clin Microbiol Infect Dis, 1988, 7: 98–102.CrossRefPubMedGoogle Scholar
  5. [5]
    Bjerketorp J, Ng Tze Chiang A, Hjort K, et al. Rapid lab-on-a-chip profiling of human gut bacteria. J Microbiol Methods, 2008, 72: 82–90.CrossRefPubMedGoogle Scholar
  6. [6]
    Verberkmoes N C, Russell A L, Shah M, et al. Shotgun metaproteomics of the human distal gut microbiota. ISME J, 2009, 3: 179–189.CrossRefPubMedGoogle Scholar
  7. [7]
    Tuohy K M, Gougoulias C, Shen Q, et al. Studying the human gut microbiota in the trans-omics era — focus on metagenomics and metabonomics. Curr Pharm Des, 2009, 15: 1415–1427.CrossRefPubMedGoogle Scholar
  8. [8]
    Fujimura K E, Slusher NA, Cabana M D, et al. Role of the gut microbiota in defining human health. Expert Rev Anti Infect Ther, 2010, 8:435–454.PubMedCentralCrossRefPubMedGoogle Scholar
  9. [9]
    Bik E M, Long C D, Armitage G C, et al. Bacterial diversity in the oral cavity of 10 healthy individuals. ISME J, 2010, 4: 962–974.PubMedCentralCrossRefPubMedGoogle Scholar
  10. [10]
    Keijser B J, Zaura E, Huse S M, et al. Pyrosequencing analysis of the oral microflora of healthy adults. J Dent Res, 2008, 87: 1016–1020.CrossRefPubMedGoogle Scholar
  11. [11]
    Zaura E, Keijser B J, Huse S M, et al. Defining the healthy ‘core microbiome’ of oral microbial communities. BMC Microbiol, 2009, 9: 259.PubMedCentralCrossRefPubMedGoogle Scholar
  12. [12]
    Reyes A, Haynes M, Hanson N, et al. Viruses in the faecal microbiota of monozygotic twins and their mothers. Nature, 2010, 466:334–338.PubMedCentralCrossRefPubMedGoogle Scholar
  13. [13]
    van Vliet M J, Harmsen H J, de Bont E S, et al. The role of intestinal microbiota in the development and severity of chemotherapy-induced mucositis. PLoS Pathog, 2010, 62: 1223–1236.Google Scholar
  14. [14]
    Manichanh C, Varela E, Martinez C, et al. The gut microbiota predispose to the pathophysiology of acute postradiotherapy diarrhea. Am J Gastroenterol, 2008, 103:1754–1761.CrossRefPubMedGoogle Scholar
  15. [15]
    Stecher B, Chaffron S, Kappeli R, et al. Like will to like: Abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathog, 2010, 6: e1000711.Google Scholar
  16. [16]
    Bailey M T, Dowd S E, Parry N M, et al. Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium. Infect Immun, 2010, 78:1509–1519.PubMedCentralCrossRefPubMedGoogle Scholar
  17. [17] Walk S T, Young V B. Emerging insights into antibiotic-associated diarrhea and clostridium difficile infection through the lens of microbial ecology. Interdiscip Perspect Infect Dis, 2008, 125081.Google Scholar
  18. [18]
    Wilson K H. The microecology of Clostridium difficile. Clin Infect Dis, 1993, 16: S214–S218.CrossRefGoogle Scholar
  19. [19]
    van Vliet M J, Tissing W J, Dun C A, et al. Chemotherapy treatment in pediatric patients with acute myeloid leukemia receiving antimicrobial prophylaxis leads to a relative increase of colonization with potentially pathogenic bacteria in the gut. Clin Infect Dis, 2009, 49: 262–270.CrossRefPubMedGoogle Scholar
  20. [20]
    Zhang M, Zhang C, Du H, et al. Pattern extraction of structural responses of gut microbiota to rotavirus infection via multivariate statistical analysis of clone library data. FEMS Microbiol Ecol, 2009, 70: 21–29.CrossRefPubMedGoogle Scholar
  21. [21]
    Gori A, Tincati C, Rizzardini G, et al. Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis. J Clin Microbiol, 2008, 46:757–758.PubMedCentralCrossRefPubMedGoogle Scholar
  22. [22]
    Tanaka K, Sawamura S, Satoh T, et al. Role of the indigenous microbiota in maintaining the virus-specific CD8 memory T cells in the lung of mice infected with murine cytomegalovirus. J Immunol, 2007, 178: 5209–5216.CrossRefPubMedGoogle Scholar
  23. [23]
    Filoche S, Wong L, Sissons C H. Oral biofilms: Emerging concepts in microbial ecology. J Dent Res, 2010, 89: 8–18.CrossRefPubMedGoogle Scholar
  24. [24]
    Spiller R, Garsed K. Infection, inflammation, and the irritable bowel syndrome. Dig Liver Dis, 2009, 41: 844–849.CrossRefPubMedGoogle Scholar
  25. [25]
    Bohle L A, Brede D A, Diep D B, et al. The mucus adhesion promoting protein (MapA) of Lactobacillus reuteri is specifically degraded to an antimicrobial peptide. Appl Environ Microbiol, 2010, 76:7306–7309.PubMedCentralCrossRefPubMedGoogle Scholar
  26. [26]
    Medellin-Pena M J, Griffiths M W. Effect of molecules secreted by Lactobacillus acidophilus strain La-5 on Escherichia coli O157: H7 colonization. Appl Environ Microbiol, 2009, 75: 1165–1172.PubMedCentralCrossRefPubMedGoogle Scholar
  27. [27]
    Doron S I, Hibberd P L, Gorbach S L. Probiotics for prevention of antibiotic-associated diarrhea. J Clin Gastroenterol, 2008, 42: S58-S63.CrossRefGoogle Scholar
  28. [28]
    Surawicz C M, McFarland L V, Greenberg R N, et al. The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii. Clin Infect Dis, 2000, 31: 1012–1017.CrossRefPubMedGoogle Scholar
  29. [29]
    Anukam K C, Osazuwa E O, Osadolor H B, et al. Yogurt containing probiotic Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 helps resolve moderate diarrhea and increases CD4 count in HIV/AIDS patients. J Clin Gastroenterol, 2008, 42: 239–243.PubMedGoogle Scholar
  30. [30]
    Reid G, Bruce A W. Low vaginal pH and urinary-tract infection. Lancet, 1995, 346: 1704.CrossRefPubMedGoogle Scholar
  31. [31]
    Rea M C, Clayton E, O’Connor PM, et al. Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains. J Med Microbiol, 2007, 56: 940–946.CrossRefPubMedGoogle Scholar
  32. [32]
    Shanahan F. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Host-microbe interactions in the gut: Target for drug therapy, opportunity for drug discovery. Clin Exp Immunol, 2010, 160: 92–97.PubMedCentralCrossRefPubMedGoogle Scholar
  33. [33] Mai V, Ukhanova M, Visone L, et al. Bacteriophage administration reduces the concentration of listeria monocytogenes in the gastrointestinal tract and its translocation to spleen and liver in experimentally infected mice. Int J Microbiol, 2010, 624234.Google Scholar
  34. [34]
    Possemiers S, Bolca S, Verstraete W, et al. The intestinal microbiome: A separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals. Fitoterapia, 2010, 82: 53–66.CrossRefPubMedGoogle Scholar

Copyright information

© Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Lanjuan Li
    • 1
    • 2
  • Yanfei Chen
    • 1
    • 2
  1. 1.The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina
  2. 2.Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesHangzhouChina

Personalised recommendations