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A Polyamine-glyceraldehyde Derivative with Anti-tumour Activity

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Summary

A product derived from dl-glyceraldehyde and a synthetic polyamine N,N′-bis-(γ-aminopropyl) diaminoethane markedly inhibited the growth of Rd/3 sarcoma in rats.

Zusammenfassung

Eine Derivatsubstanz des dl-Glyeerinaldehyd und eines synthetischen Polyamin N,N′-bis-(γ-aminopropyl)diaminoethan übt eine ausgeprägte Hemmung auf das Wachstum des Rd/3 Sarkomas in Ratten aus.

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References

  • Apple, M. A., Greenberg, D.M.: Arrest of cancer in mice by therapy with normal metabolites I. 2-oxopropanal. Cancer Chemother. Rep. 51, 455–464 (1967).

    CAS  Google Scholar 

  • Ellis,G.P.: The Maillard reaction. Adv. Carbohydrate Chem. 14, 63–134 (1959).

    Article  CAS  Google Scholar 

  • Israel, M., Rosenfield, J. S., Modest, E. J.: Analogs of spermine and spermidine. I. Synthesis of polymethylenepolyamines by reduction of cyanoethylated a, w-alkylenediamines. J. med. Chem. 7, 710–716 (1964).

    CAS  Google Scholar 

  • Raina, A.: Studies on the determination of spermidine and spermine and their metabolism in the developing chick embryo. Acta physiol. stand. 60, Suppl. 218 (1963).

    Google Scholar 

  • Van Alphen,J.: On aliphatic polyamines I. Rec. Tray. chini. du Pays-bas 55, 412–418 (1936).

    Article  Google Scholar 

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© 1971 Springer-Verlag Berlin Heidelberg

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Neish, W.J.P. (1971). A Polyamine-glyceraldehyde Derivative with Anti-tumour Activity. In: Hamperl, H., Hecker, E., Schmidt, C.G. (eds) Zeitschrift für Krebsforschung und klinische Onkologie / Cancer Research and Clinical Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-42449-0_22

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  • DOI: https://doi.org/10.1007/978-3-662-42449-0_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-42180-2

  • Online ISBN: 978-3-662-42449-0

  • eBook Packages: Springer Book Archive

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